DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10960 and slc2a11

DIOPT Version :9

Sequence 1:	NP_648605.1	Gene:	CG10960 / 39458	FlyBaseID:	FBgn0036316	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	XP_004910639.2	Gene:	slc2a11 / 100496562	XenbaseID:	XB-GENE-980809	Length:	508	Species:	Xenopus tropicalis

Alignment Length:	525	Identity:	141/525 - (26%)
Similarity:	231/525 - (44%)	Gaps:	74/525 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 HDQENLLGNMVHTSTSNNSQKWPQYVAALAAAGGAFAAG---TVLGWTSPA--------ETEIVD 113
            |.:|..|||..:.......:.....:.| |..||.|..|   |::  .:|.        ||.:..
Frog     4 HGREGELGNAQNAGCRGQGRVLLLTMCA-AGIGGTFQYGYNLTII--NAPTMHIQKFVNETWLER 65

  Fly   114 RGEGYDFPVDKDQFSWVGSAMTLGAACVCIPIGFLINMIGRKWTMLFLVLPFILGWTMLIW---- 174
            .|:..|..|....:|.:.|...||.....:..|.:...:|||.::||..| |::...:|..
Frog    66 NGQQLDSQVITLIWSIIVSVYPLGGFLGALLAGPMAIRLGRKKSLLFNNL-FVILSAILCGLSRP 129

  Fly   175 AVNVSMLYASRFILGIAGGAFCVTAPMYTGEIAQKEIRGTLGSFFQLMITIGILFVYAVG----A 235
            |.:..|:...|.:.|:..|......|||..|.|..::|||:.........:|::....:|    .
Frog   130 AKSFEMIVLGRILAGLNSGVSMNVQPMYLSESAPMKLRGTVAMSSAAFTALGLVLGQVIGLREIL 194

  Fly   236 GVKIFWLSIICG----------ILPLIFGAIFFFMPESPTYLV--SKDRSENAIKSIQWLRGKEY 288
            |.:..|..::..          :||        ::||||.||:  .||: ::.|.::|.|||..
Frog   195 GSEECWPFLLASNAVPAMLQLFVLP--------WLPESPRYLLIDLKDK-DSCICALQRLRGHS- 249

  Fly   289 DYEPELAELRETDRETKANKVNVWAALNR-PVTRKALAISMGLMFFQQVCGINAVIFYASRIFLE 352
            |...|:.::.......|..:......|.| |..|:.:...:.|....|:||.:::.||||.||.|
Frog   250 DLSLEMEQMLAEQAAIKGQRPKSLCELIREPTLRRQILTIVVLSSAMQLCGNDSMYFYASSIFQE 314

  Fly   353 ANTGIE-AEWATILIGIMQVVATFVSTLVVDKLGRRILLLASGISMAISTTAIGVYFFLQKQDAA 416
            |...:| .::..|..|..::|.:...|:.:|::|||.|:: .|.|: :|..|:.....|.:|.
Frog   315 AGIPLEKIQYVVIGTGSCELVTSITCTVFIDRVGRRALVM-GGYSL-MSVWAVVFMVALSQQG-- 375

  Fly   417 QVVSLGWLPVASL-CLFIIMFSIGYGP--VPWLMMGELFATDIKGFAGSLAGTSNWLLAFVVTKT 478
               .:.|:|..|: |:|..:.|.|.||  |..:|.||:|....:..|..:.|:..|::.||:...
Frog   376 ---HVSWMPYLSMVCIFAYILSFGIGPAGVTGIMPGEIFDQMARPAAYMICGSLIWIMLFVIGLA 437

  Fly   479 FVNLNDGLGIGGTFWLFAGLTVVGV---IFVYFAVPETKGKSLNEIQQE----------LAGNRS 530
            |..:..|||    .:.|....||.|   ::|...:||||||||.||.::          :|...|
Frog   438 FPFILQGLG----HFCFIPFLVVCVSTALYVGIFLPETKGKSLLEITEDFTKHSVKRKNVANGWS 498

  Fly   531 TPQAI 535
            .||.|
Frog   499 GPQEI 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10960	NP_648605.1	MFS_1	117..474	CDD:284993	99/381 (26%)
CG10960	NP_648605.1	MFS	118..508	CDD:119392	110/417 (26%)
slc2a11	XP_004910639.2	MFS_GLUT_Class2	28..479	CDD:340990	129/475 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000