DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10960 and slc2a15a

DIOPT Version :9

Sequence 1:	NP_648605.1	Gene:	CG10960 / 39458	FlyBaseID:	FBgn0036316	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	XP_017950703.2	Gene:	slc2a15a / 100494397	XenbaseID:	XB-GENE-992550	Length:	559	Species:	Xenopus tropicalis

Alignment Length:	562	Identity:	162/562 - (28%)
Similarity:	245/562 - (43%)	Gaps:	109/562 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 RQPVKIVKASDNGRTSSTPHDQENLLGNMVHT--STSNNSQK---WPQYVAALAAA-GGAFAAG- 98
            |.|.::......|.......:|:....||.|.  .|...|:|   |...:||:..| |.:|..|
Frog     5 RVPTQLDMEKQQGDWELERLNQQKQDRNMEHLDHETGKISRKGFSWQLIMAAVVGALGSSFLYGY 69

  Fly    99 --TVLGWTSPAETEIVDR--GEGYDFPVDKDQFSWVGSAMT-------LGAACVCIPIGFLINMI 152
              :|:...|....|:.:.  ...|::.|.:...|.:.|...       |..|.:.||   ::|.:
Frog    70 NLSVVNAPSVYIQELYNESWSARYNYTVSRGTISILWSVTVSIFAIGGLVGALIVIP---MVNFL 131

  Fly   153 GRKWTMLFLVLPFILGWTMLIWAVNVS----MLYASRFILGIAGGAFCVTAPMYTGEIAQKEIRG 213
            |||.||| |...|.:...:|:...||:    |:...|||:||.||....|.|||..|::.|.|||
Frog   132 GRKGTML-LNNVFAITAALLMSLSNVAGIPEMMILGRFIMGIDGGIALSTLPMYLNEVSPKHIRG 195

  Fly   214 TLGSFFQLMITIGILFVYAVGA----GVKIFWLSIICGILPLIFGAIFF----------FMPESP 264
            :||....::|.:|:.....:|.    |.:..|        |.:||.|..          |.||||
Frog   196 SLGQVTAILICVGVFVGQVLGLPELFGKESQW--------PCLFGFIMIPALIQLVVLPFFPESP 252

  Fly   265 TYLV----SKDRSENAIKSIQWLRGKEYDYEPELAELR--------ETDRETKANKVNVWAALNR 317
            .||:    .:.|:|.|............|.|..|||.|        ......|...|. |..:..
Frog   253 RYLLLEKQDRKRAEKAFCIFLGRNDVSQDIEDVLAETRIQRNLRLVSVPELFKTRSVK-WQIITV 316

  Fly   318 PVTRKALAISMGLMFFQQVCGINAVIFYASRIFLEANTGIEAE---WATILIGIMQVVATFVSTL 379
            .||..|          .|:||:||:.||.:.||.||  ||:.:   :.|:..|.::::|:.:|.:
Frog   317 IVTMAA----------YQLCGLNAIWFYTNSIFSEA--GIQPDKIPYITLSTGGIEILASVISGM 369

  Fly   380 VVDKLGRRILLLASGISMAISTTAIGVYFFLQKQDAAQVVSL------GWLPVASL-CLF--IIM 435
            .|::|||||||:.   ...:.|...|:.          .|||      .|:|..|: |:.  |..
Frog   370 TVERLGRRILLIG---GFGLMTLFFGIL----------TVSLTFQHHAPWIPYISIVCILGVIAS 421

  Fly   436 FSIGYGPVPWLMMGELFATDIKGFAGSLAGTSNWLLAFVVTKTFVNLNDGLGIGGTFWLFAGLTV 500
            |.||.|.:|::::||.|....:..|..:||:.||:..|.|...|..:.:||| ...|.:||.:.:
Frog   422 FCIGPGGIPFVLVGEFFQQSQRPAAFMIAGSVNWISNFAVGLLFPLIQEGLG-NYCFLIFAAICL 485

  Fly   501 VGVIFVYFAVPETKGKSLNEIQQELA----------GNRSTP 532
            .|.:::||.:||||.|:.:||.|..|          ||...|
Frog   486 AGTLYLYFILPETKNKTFSEIDQAFAKMNGISSATKGNEIHP 527

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10960	NP_648605.1	MFS_1	117..474	CDD:284993	118/405 (29%)
CG10960	NP_648605.1	MFS	118..508	CDD:119392	128/438 (29%)
slc2a15a	XP_017950703.2	MFS_GLUT_Class2	55..506	CDD:340990	144/489 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000