DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10960 and slc2a7

DIOPT Version :9

Sequence 1:	NP_648605.1	Gene:	CG10960 / 39458	FlyBaseID:	FBgn0036316	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	NP_001120033.1	Gene:	slc2a7 / 100144999	XenbaseID:	XB-GENE-5811422	Length:	501	Species:	Xenopus tropicalis

Alignment Length:	491	Identity:	139/491 - (28%)
Similarity:	224/491 - (45%)	Gaps:	59/491 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    84 YVAALAAA-GGAFAAG---TVLG-------------WTSPAETEIVDRGEGYDFPVDKDQFSWVG 131
            ::|..|.. ||||..|   :::.             |.|..::.:   .||:...:    :|.:.
Frog    21 FLAVCAVGIGGAFQYGYNVSIINAPTRQIQQFINNTWYSRHQSNL---EEGWLTLI----WSVIA 78

  Fly   132 SAMTLGAACVCIPIGFLINMIGRKWTMLF-----LVLPFILGWTMLIWAVNVSMLYASRFILGI- 190
            |..|||........|.|.:.:|||.|:|.     ::..|::|  :...:....:|...|.|:||
Frog    79 SVFTLGGLLGTHIGGHLADKLGRKKTLLMNNVLAILAAFLMG--IAYPSGCFELLIVGRLIIGIN 141

  Fly   191 AGGAFCVTAPMYTGEIAQKEIRGTLGSFFQLMITIGILFVYAV------GAGVKIFWLSIICGIL 249
            ||...|| .|:|.||||.:.|||.......:.:|.||.....|      |.|...::|...|.|.
Frog   142 AGIGLCV-QPLYLGEIAPRHIRGLTTVGMNIFLTGGIFTGQLVGLRELFGGGDNWYFLLPTCCIP 205

  Fly   250 PLIFGAIFFFMPESPTYLVSKDRSE-NAIKSIQWLRGKEYDYEPELAE-LRETDRETKANKVNVW 312
            .:|..|...:.||||.||:.:::.| ...|:::.|.|.|: |:||:.: |:|:..........::
Frog   206 AIIQLASLPWFPESPRYLLIENKDEYQCQKALKMLYGSEH-YQPEMDDILKESCALNGEKPKTIF 269

  Fly   313 AALNRPVTRKALAISMGLMFFQQVCGINAVIFYASRIFLEANTGIEAE---WATILIGIMQVVAT 374
            ...:....|..|.|.:.....||:.||||:.|||:.:|.:|  ||.|.   :.|:..|:.:.:..
Frog   270 QLFSDRTVRWQLVIIILTNIGQQLSGINAIYFYAAYVFTKA--GIPANNIPYVTLGTGLCECLTA 332

  Fly   375 FVSTLVVDKLGRRILLLASGISMAISTTAIGVYFFLQKQDAAQVVSLGWLPVASLC---LFIIMF 436
            ....|::|..|||||::.....||...|.:.:  .|..||.     ..|:|..|:.   .||:.|
Frog   333 LTCGLLIDIAGRRILIIGGYTLMAFWCTILTL--TLTFQDV-----YPWIPYLSMSAVFAFILSF 390

  Fly   437 SIGYGPVPWLMMGELFATDIKGFAGSLAGTSNWLLAFVVTKTFVNLNDGLGIGGTFWLFAGLTVV 501
            .:|.|.|...:..|||....:..|..::|:..|:..|.:...|..|.:||. ...|..|....::
Frog   391 GLGPGGVTNTLTAELFTQSSRSAAFRISGSVGWITFFTIGMIFPFLVNGLN-QYCFLFFFVECLL 454

  Fly   502 GVIFVYFAVPETKGKSLNEIQQELAGNRSTPQAIPA 537
            ...|::|.|||||.||..||::|.. .|:..|:.|:
Frog   455 TASFIFFIVPETKNKSFLEIKKEFQ-KRNVGQSYPS 489

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10960	NP_648605.1	MFS_1	117..474	CDD:284993	107/376 (28%)
CG10960	NP_648605.1	MFS	118..508	CDD:119392	114/409 (28%)
slc2a7	NP_001120033.1	MFS_GLUT_Class2	23..474	CDD:340990	133/471 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910