DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sf3a2 and sap62

DIOPT Version :9

Sequence 1:	NP_648603.1	Gene:	Sf3a2 / 39456	FlyBaseID:	FBgn0036314	Length:	264	Species:	Drosophila melanogaster
Sequence 2:	NP_596585.1	Gene:	sap62 / 2540622	PomBaseID:	SPBC21C3.05	Length:	217	Species:	Schizosaccharomyces pombe

Alignment Length:	215	Identity:	127/215 - (59%)
Similarity:	159/215 - (73%)	Gaps:	12/215 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDFQNRAGGKTGSGGVASWSETNRDRKERLRQLALETIDLNKDPYFMKNHLGSYECKLCLTLHNN 65
            ||:|||||.:.|.||||.:.|||..|:||||:||||||||:||||.||||||::||:||||.|.|
pombe     1 MDYQNRAGVRFGGGGVAGYQETNAARRERLRKLALETIDLSKDPYLMKNHLGTFECRLCLTTHAN 65

  Fly    66 EGSYLAHTQGKKHQDNLARRAAKEAKE----APSSLLAPEKPRVEPKK-FVKIGRPGYRVTKQRE 125
            |.|||.||||||||.|||||.|.|.|:    ||..||...:..|:.|| .||||||||:|:|.||
pombe    66 ENSYLTHTQGKKHQTNLARRQALENKKSQENAPQVLLGISQSHVQVKKSVVKIGRPGYKVSKIRE 130

  Fly   126 LSNGQQSLLFQVDYPEITESIVPRHRFMSAYEQKIEPPDRKWQYLLFAAEPYETIGFKVPSREVE 190
            ..:|:..|.||:.||:|..:..||:|.||||||::|.||||:|||:.||||||:|.||     ::
pombe   131 AESGKFGLRFQIKYPDIEVNAKPRYRIMSAYEQRVEAPDRKFQYLVVAAEPYESIAFK-----ID 190

  Fly   191 KSEGKFWTHWNRDTK--QFF 208
            ::.||||::|:..|.  |||
pombe   191 RAPGKFWSYWDAPTYTIQFF 210

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sf3a2	NP_648603.1	PRP11	1..214	CDD:227571	127/215 (59%)
		ZnF_U1	52..85	CDD:197732	24/32 (75%)
		SF3A2	129..207	CDD:293440	39/79 (49%)
sap62	NP_596585.1	PRP11	1..217	CDD:227571	127/215 (59%)
		ZnF_U1	54..85	CDD:197732	23/30 (77%)
		SF3A2	134..204	CDD:293440	38/74 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	109	1.000	Domainoid score	I1629
eggNOG	1	0.900	-	-		E1_COG5246
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	250	1.000	Inparanoid score	I788
OMA	1	1.010	-	-		QHG53497
OrthoFinder	1	1.000	-	-		FOG0004594
OrthoInspector	1	1.000	-	-		oto101932
orthoMCL	1	0.900	-	-		OOG6_102158
Panther	1	1.100	-	-	LDO	PTHR23205
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1286
SonicParanoid	1	1.000	-	-		X3809
TreeFam	1	0.960	-	-
	13	12.860