DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Atg1 and AT1G49180

DIOPT Version :9

Sequence 1:	NP_001163433.1	Gene:	Atg1 / 39454	FlyBaseID:	FBgn0260945	Length:	855	Species:	Drosophila melanogaster
Sequence 2:	NP_175344.2	Gene:	AT1G49180 / 841341	AraportID:	AT1G49180	Length:	408	Species:	Arabidopsis thaliana

Alignment Length:	383	Identity:	101/383 - (26%)
Similarity:	175/383 - (45%)	Gaps:	56/383 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 EYSSKDMLGHGAFAVVYKGRHRKKHMPVAIKCI-TKKGQLKTQNLLGKEIKILKELTELHHENVV 71
            :|.:|..|.....:.|:..:|:.......:||. ..|.....::.|..|::.   |:.:.|.|::
plant     6 DYIAKSKLSESLTSTVWLAKHKLTGEEAVMKCFDLSKLNRNLRDCLNNELEF---LSSVDHPNII 67

  Fly    72 ALLDCKESQDCVSLVMEYCNGGDLADYLSVKGTLSEDTVRLFLVQLAGAMKALYTKGIVHRDLKP 136
            .||...:..|.:.:|:|||:||.|:.|:...|.:.||..:.|:.|:...::.::...|:||||||
plant    68 RLLHVSQDDDFLVMVLEYCDGGTLSSYIQRYGRVEEDIAKRFMKQIGAGLEIIHDNHIIHRDLKP 132

  Fly   137 QNILLSHNYGKTLPAPSKITLKIADFGFARFLNEGAMAATLCGSPMYMAPEVIMSLQYDSKADLW 201
            :|||:.       .:...:.||||||..||.|:.|....|:||||.||||||:...:|:.|||:|
plant   133 ENILID-------GSGDDLVLKIADFSLARKLHPGKYLETVCGSPFYMAPEVLQFQRYNEKADMW 190

  Fly   202 SLGTIVYQCLTGKAPFYAQTPNELKSYYEQNANLAPKIP------SGVSPDLRDLLLCLLRRNSK 260
            |:|.|:::.|.|..||......::.    :|...:..:|      ..:.||..|:...||..|..
plant   191 SVGAILFELLHGYPPFRGNNNVQVL----RNIKSSTALPFSRLILQQMHPDCIDVCSRLLSINPA 251

  Fly   261 DRISYESF-FVHRF------------------LQGKKAAVSPG----EPSQAANLRRRVSKSGVL 302
            ..:..|.| |:.|.                  .:.:|.|...|    :.||.|.|.:|:.::.:.
plant   252 ATLGIEDFPFLGRIKNSRVWVKDTTFSSRQHGTRERKVATINGRLQFDLSQDAYLPQRLLENLMY 316

  Fly   303 ---PVDMPPLGGTPPA---------KAKSPLQQQLEQELKLVKLAEQQQKEREEQEAQ 348
               .::|..:.|.|.:         |..|.|.::.:|:....::.......:|..:.|
plant   317 IYNTIEMARVTGVPTSYLISRGESIKVLSQLLRKAKQKTWFFQMLRSWNLNKELMKVQ 374

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Atg1	NP_001163433.1	S_TKc	9..274	CDD:214567	84/290 (29%)
		STKc_ULK1_2-like	15..273	CDD:271022	81/265 (31%)
		DUF3543	638..844	CDD:288883
AT1G49180	NP_175344.2	STKc_ATG1_ULK_like	13..261	CDD:270911	80/261 (31%)
		S_TKc	19..262	CDD:214567	79/256 (31%)
		DnaQ_like_exo	<248..321	CDD:299142	13/72 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0595
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1084750at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24348
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920