DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Atg1 and pdik1l

DIOPT Version :9

Sequence 1:	NP_001163433.1	Gene:	Atg1 / 39454	FlyBaseID:	FBgn0260945	Length:	855	Species:	Drosophila melanogaster
Sequence 2:	NP_001032789.2	Gene:	pdik1l / 569665	ZFINID:	ZDB-GENE-051113-236	Length:	341	Species:	Danio rerio

Alignment Length:	324	Identity:	84/324 - (25%)
Similarity:	142/324 - (43%)	Gaps:	70/324 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 IVGEYEYSSKDMLGHGAFAVVYKGRHRKKHMPVAIKCITKKGQLKTQNLLGKEIKILKELTELHH 67
            :..:.:|.....:|.|::.|||:...|:....||:|.|........:..| :|...|..: :..|
Zfish     2 VSSQAKYELIQEVGRGSYGVVYEAVVRQTGARVAVKKIRCHSPENVELAL-REFWALSSI-QSQH 64

  Fly    68 ENVVALLDCKESQDCVS-----------------------------------LVMEYCNGGDLAD 97
            .||:.|.:|...:|.::                                   .||::|:|||:..
Zfish    65 PNVIHLEECVLQRDALAQRMSHGSSSSLYLELVETSLKGEITFDPCCAYYMWFVMDFCDGGDMNA 129

  Fly    98 YLSVKGTLSEDTVRLFLVQLAGAMKALYTKGIVHRDLKPQNILLSHNYGKTLPAPSKITLKIADF 162
            || :....|..|...|::||..|:..|:...|:||||||.|||:|.  |:|.....:.|||:|||
Zfish   130 YL-LSRKPSRKTNTSFMLQLGSALAFLHRNQIIHRDLKPDNILISQ--GRTPAGSPEPTLKVADF 191

  Fly   163 GFARFLNEGAM------------AATLCGSPMYMAPEVIMSLQYDSKADLWSLGTIVYQCLTGKA 215
            |.::..:...:            .:|.||:..|||||| ....|.:|||:::||.|::..:....
Zfish   192 GLSKVCSGSGLNPEEPASVNKCFLSTACGTDFYMAPEV-WEGHYTAKADIFALGVIIWAMVERIT 255

  Fly   216 PFYAQTPNE-LKSYYEQNANLAP-------------KIPS---GVSPDLRDLLLCLLRRNSKDR 262
            ....:|..| |.||.:|..::.|             .||:   .::..::.|:..:|..|.::|
Zfish   256 FVDVETQKELLGSYVQQGEDIVPLGEALLENPKMELNIPARKKSMNASMKQLIREMLSANPQER 319

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Atg1	NP_001163433.1	S_TKc	9..274	CDD:214567	84/318 (26%)
		STKc_ULK1_2-like	15..273	CDD:271022	83/312 (27%)
		DUF3543	638..844	CDD:288883
pdik1l	NP_001032789.2	STKc_PDIK1L	7..331	CDD:270879	84/319 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0595
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810