DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Atg1 and si:ch211-63o20.7

DIOPT Version :9

Sequence 1:	NP_001163433.1	Gene:	Atg1 / 39454	FlyBaseID:	FBgn0260945	Length:	855	Species:	Drosophila melanogaster
Sequence 2:	NP_001038586.2	Gene:	si:ch211-63o20.7 / 566836	ZFINID:	ZDB-GENE-041001-194	Length:	357	Species:	Danio rerio

Alignment Length:	347	Identity:	97/347 - (27%)
Similarity:	146/347 - (42%)	Gaps:	118/347 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 YSSKDMLGHGAFAVVYKGRHRK------KHMPVAIK----CITKKGQLKTQNLLGKEIKILKELT 63
            |:.:..:|.|::.||:|||..:      |...||||    |..:..:|..|.|....|      |
Zfish     5 YTLQQEVGRGSYRVVFKGRVTETGWWGAKGDTVAIKRLPCCSPESIELYLQELWAMRI------T 63

  Fly    64 ELHHENVVALLDC--------------------------------KESQD--------------- 81
            ..:|.||:||.:|                                |:|:.
Zfish    64 ARNHPNVIALYNCLLQTGPRTLQPLRSSRLPLDLVESALKGRVVDKDSKTQTRNASRSKRRLISK 128

  Fly    82 ------CVS--LVMEYCNGGDLADYLSVKGTLSE--DTVRLFLVQLAGAMKALYTKGIVHRDLKP 136
                  |.:  ||||||.||||..|:..:...:|  :||   :.|:..|:..|:..|||||||||
Zfish   129 EEVPRRCFALWLVMEYCEGGDLGQYILSRPPDAECNNTV---VRQICSAIAFLHEHGIVHRDLKP 190

  Fly   137 QNILLSHNYGKTLPAPSKITLKIADFGFARFLN---EG-----AMAATLCGSPMYMAPEVIMSLQ 193
            .|:|:.    .|...|   .:|:||||.:..|:   :|     |:::| |||..||||||.....
Zfish   191 DNVLVC----LTKEGP---VMKVADFGLSNMLDNPTDGVQSRLALSST-CGSDFYMAPEVWAGRS 247

  Fly   194 YDSKADLWSLGTIVYQCLTGKAPFYAQTPN--ELKSYYE-------------QNANL-------- 235
            |.::||::|||.:.:..|. :..|.....|  :|.:|..             :|.:|
Zfish   248 YTAQADIFSLGVLFWAVLE-RITFLEDGTNQEQLGAYVMRGRWLSPLAEALCENPDLQLIIPMRT 311

  Fly   236 --APKIPSGVSPDLRDLLLCLL 255
              ||.:|...:|.:.:|||.:|
Zfish   312 RRAPPLPPPPNPSMCELLLDML 333

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Atg1	NP_001163433.1	S_TKc	9..274	CDD:214567	97/347 (28%)
		STKc_ULK1_2-like	15..273	CDD:271022	96/341 (28%)
		DUF3543	638..844	CDD:288883
si:ch211-63o20.7	NP_001038586.2	PKc_like	5..350	CDD:304357	97/347 (28%)
si:ch211-63o20.7	NP_001038586.2	S_TKc	5..346	CDD:214567	97/347 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0595
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810