DRSC/TRiP Functional Genomics Resources

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Protein Alignment Atg1 and Stk35

DIOPT Version :9

Sequence 1:NP_001163433.1 Gene:Atg1 / 39454 FlyBaseID:FBgn0260945 Length:855 Species:Drosophila melanogaster
Sequence 2:NP_001101243.1 Gene:Stk35 / 311419 RGDID:1310247 Length:604 Species:Rattus norvegicus


Alignment Length:333 Identity:92/333 - (27%)
Similarity:136/333 - (40%) Gaps:96/333 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly     9 YSSKDMLGHGAFAVVYKGRHRKKHMPVAIKCITKKGQLKTQNLLGKEIKILKELTEL--HHENVV 71
            ||....:|.|::.|||:....:....||:|.|........:..|.:    ...||.|  .|:|:|
  Rat   272 YSLLAEIGRGSYGVVYEAVAGRSGAKVAVKKIRCDAPENVELALAE----FWALTSLKRRHQNIV 332

  Fly    72 ALLDC---------------KESQDCVSL----------------------VMEYCNGGDLADYL 99
            ...:|               |.||..:.|                      |||||.||||..|:
  Rat   333 QFEECVLQRNGLAQRMSHGNKNSQLYLRLVETSLKGERILGYAEEPCYLWFVMEYCEGGDLNQYV 397

  Fly   100 SVKGTLSE----DTVRLFLVQLAGAMKALYTKGIVHRDLKPQNILLSHNYGKTLPAPSKITLKIA 160
                 ||.    .|.:.|::||..|:..|:...||||||||.|||::...|..:       ||:|
  Rat   398 -----LSRRPDPATNKSFMLQLTSAIAFLHKNHIVHRDLKPDNILITERSGTPI-------LKVA 450

  Fly   161 DFGFARFL-------NEGAM-----------AATLCGSPMYMAPEVIMSLQYDSKADLWSLGTIV 207
            |||.::..       .||..           .::.|||..|||||| ....|.:|||:::||.|:
  Rat   451 DFGLSKVCAGLAPRGKEGNQDNKDVNVNKYWLSSACGSDFYMAPEV-WEGHYTAKADIFALGIII 514

  Fly   208 YQCLTGKAPFYAQTPNE-LKSYYEQNANLAP-------------KIP----SGVSPDLRDLLLCL 254
            :..:.......::|..| |.:|.:|...:.|             .||    :.:|..::.||..:
  Rat   515 WAMIERITFIDSETKKELLGTYIKQGTEIVPVGEALLENPKMELHIPQKRRTSMSEGVKQLLKDM 579

  Fly   255 LRRNSKDR 262
            |..|.:||
  Rat   580 LAANPQDR 587

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Atg1NP_001163433.1 S_TKc 9..274 CDD:214567 92/333 (28%)
STKc_ULK1_2-like 15..273 CDD:271022 90/327 (28%)
DUF3543 638..844 CDD:288883
Stk35NP_001101243.1 STKc_PDIK1L 271..599 CDD:270879 92/333 (28%)
S_TKc 272..593 CDD:214567 92/333 (28%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0595
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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