DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Atg1 and T07F12.4

DIOPT Version :9

Sequence 1:	NP_001163433.1	Gene:	Atg1 / 39454	FlyBaseID:	FBgn0260945	Length:	855	Species:	Drosophila melanogaster
Sequence 2:	NP_001368727.1	Gene:	T07F12.4 / 180763	WormBaseID:	WBGene00020324	Length:	329	Species:	Caenorhabditis elegans

Alignment Length:	279	Identity:	101/279 - (36%)
Similarity:	152/279 - (54%)	Gaps:	30/279 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 EYEY--SSKDMLGHGAFAVVYKGRHRKKHMPVAIKCITKKGQLKTQNLLGKEIKILKELTELHHE 68
            :|||  |...|:|.|||..|:||..:.....:|||.:.|      .::...|:|::|   ||:.|
Worm    55 KYEYMDSVDAMIGMGAFGAVFKGSLKDSSNSIAIKRMLK------VHVKESELKMIK---ELNSE 110

  Fly    69 NVVALLD-CKESQDCVSLVMEYCNGGDLADY---LSVKGTLSEDTVRLFLVQLAGAMKALYTKGI 129
            .:|.:|| |........|:||.|: .||..:   :||||.|:....||.|..:|...||||...|
Worm   111 YLVGVLDICNFDDFFCCLIMELCD-CDLDHHMRNISVKGRLNPSNFRLLLDNIARGYKALYELKI 174

  Fly   130 VHRDLKPQNILLSHNYGKTLPAPSKITLKIADFGFARFL-NEGAMAATLCGSPMYMAPEV----I 189
            ||||:||||||:::.......|.::||    |||.:|.| |||.....:.|:..||||||    :
Worm   175 VHRDIKPQNILITYTDASKQIACARIT----DFGISRTLDNEGEELCNVAGTFYYMAPEVGANLL 235

  Fly   190 MSLQYDSKADLWSLGTIVYQCLTGKAPFYAQTPNELKSYYEQNANL----APKIPSGVSPDLRDL 250
            .:.|||||.|:||:|.::|||:||:.||...:..:| ..|...||.    .|::|..:|.::..:
Worm   236 KTCQYDSKVDMWSIGCLLYQCVTGEVPFDECSLCKL-FLYVAGANFDAYDPPELPDELSQEVSGI 299

  Fly   251 LLCLLRRNSKDRISYESFF 269
            :..||:.::..|.:...|:
Worm   300 IQSLLQLDTTQRCTPTQFY 318

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Atg1	NP_001163433.1	S_TKc	9..274	CDD:214567	99/276 (36%)
		STKc_ULK1_2-like	15..273	CDD:271022	96/268 (36%)
		DUF3543	638..844	CDD:288883
T07F12.4	NP_001368727.1	S_TKc	66..316	CDD:214567	95/264 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0595
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24348
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910