Protein Alignment Atg1 and PDIK1L

DIOPT Version :10

• Sequence 1: NP_001163433.1
• Gene: Atg1 / 39454
• FlyBaseID: FBgn0260945
• Length: 855
• Species: Drosophila melanogaster
• Sequence 2: NP_690048.1
• Gene: PDIK1L / 149420
• HGNCID: 18981
• Length: 341
• Species: Homo sapiens
• Alignment Length: 370
• Identity: 97/370 - (26%)
• Similarity: 153/370 - (41%)
• Gaps: 99/370 - (26%)

  Fly    15 LGHGAFAVVYKGRHRKKHMPVAIKCITKKGQLKTQNLLGKEIKILKELTELHHENVVALLDCKES 79
            :|.|::.|||:...||....||:|.|........:..| :|...|..: :..|.||:.|.:|...
Human    14 VGRGSYGVVYEAVIRKTSARVAVKKIRCHAPENVELAL-REFWALSSI-KSQHPNVIHLEECILQ 76

  Fly    80 QDCV-------------------SL----------------VMEYCNGGDLADY-LSVKGTLSED 108
            :|.:                   ||                ||::|:|||:.:| ||.|.....:
Human    77 KDGMVQKMSHGSNSSLYLQLVETSLKGEIAFDPRSAYYLWFVMDFCDGGDMNEYLLSRKPNRKTN 141

  Fly   109 TVRLFLVQLAGAMKALYTKGIVHRDLKPQNILLSHNYGKTLPAPSKITLKIADFGFARFLNEG-- 171
            |  .|::||:.|:..|:...|:||||||.|||:|.....|  :..:.|||:||||.::..:..
Human   142 T--SFMLQLSSALAFLHKNQIIHRDLKPDNILISQTRLDT--SDLEPTLKVADFGLSKVCSASGQ 202

  Fly   172 ----------AMAATLCGSPMYMAPEVIMSLQYDSKADLWSLGTIVYQCLTGKAPFYAQTPNE-L 225
                      ...:|.||:..|||||| ....|.:|||:::||.|::..|........:|..| |
Human   203 NPEEPVSVNKCFLSTACGTDFYMAPEV-WEGHYTAKADIFALGIIIWAMLERITFIDTETKKELL 266

  Fly   226 KSYYEQNANLAPKIPSGVSPDLRDLLLCLLRRNSKDRISYESFFVHRFLQGKKAAVSPGEPSQAA 290
            .||.:|...:.|...:.:.....:||:.:.:::...|:..   .:...|              ||
Human   267 GSYVKQGTEIVPVGEALLENPKMELLIPVKKKSMNGRMKQ---LIKEML--------------AA 314

  Fly   291 NLRRRVSKSGVLPVDMPPLGGTPPAKAKSPLQQQLEQELKLVKLA 335
            |           |.|.|               ...|.||:||::|
Human   315 N-----------PQDRP---------------DAFELELRLVQIA 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atg1	NP_001163433.1	STKc_ULK1_2-like	15..273	CDD:271022	84/306 (27%)
		DUF3543	640..844	CDD:463451
PDIK1L	NP_690048.1	STKc_PDIK1L	7..331	CDD:270879	95/366 (26%)