Protein Alignment Atg1 and STK35

DIOPT Version :9

• Sequence 1: NP_001163433.1
• Gene: Atg1 / 39454
• FlyBaseID: FBgn0260945
• Length: 855
• Species: Drosophila melanogaster
• Sequence 2: NP_543026.2
• Gene: STK35 / 140901
• HGNCID: 16254
• Length: 534
• Species: Homo sapiens
• Alignment Length: 333
• Identity: 92/333 - (27%)
• Similarity: 136/333 - (40%)
• Gaps: 96/333 - (28%)

  Fly     9 YSSKDMLGHGAFAVVYKGRHRKKHMPVAIKCITKKGQLKTQNLLGKEIKILKELTEL--HHENVV 71
            ||....:|.|::.|||:....:....||:|.|........:..|.:    ...||.|  .|:|||
Human   202 YSLLAEIGRGSYGVVYEAVAGRSGARVAVKKIRCDAPENVELALAE----FWALTSLKRRHQNVV 262

  Fly    72 ALLDC---------------KESQDCVSL----------------------VMEYCNGGDLADYL 99
            ...:|               |.||..:.|                      |||:|.||||..|:
Human   263 QFEECVLQRNGLAQRMSHGNKSSQLYLRLVETSLKGERILGYAEEPCYLWFVMEFCEGGDLNQYV 327

  Fly   100 SVKGTLSE----DTVRLFLVQLAGAMKALYTKGIVHRDLKPQNILLSHNYGKTLPAPSKITLKIA 160
                 ||.    .|.:.|::||..|:..|:...||||||||.|||::...|..:       ||:|
Human   328 -----LSRRPDPATNKSFMLQLTSAIAFLHKNHIVHRDLKPDNILITERSGTPI-------LKVA 380

  Fly   161 DFGFARFL-------NEGAM-----------AATLCGSPMYMAPEVIMSLQYDSKADLWSLGTIV 207
            |||.::..       .||..           .::.|||..|||||| ....|.:|||:::||.|:
Human   381 DFGLSKVCAGLAPRGKEGNQDNKNVNVNKYWLSSACGSDFYMAPEV-WEGHYTAKADIFALGIII 444

  Fly   208 YQCLTGKAPFYAQTPNE-LKSYYEQNANLAP-------------KIP----SGVSPDLRDLLLCL 254
            :..:.......::|..| |.:|.:|...:.|             .||    :.:|..::.||..:
Human   445 WAMIERITFIDSETKKELLGTYIKQGTEIVPVGEALLENPKMELHIPQKRRTSMSEGIKQLLKDM 509

  Fly   255 LRRNSKDR 262
            |..|.:||
Human   510 LAANPQDR 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atg1	NP_001163433.1	S_TKc	9..274	CDD:214567	92/333 (28%)
		STKc_ULK1_2-like	15..273	CDD:271022	90/327 (28%)
		DUF3543	638..844	CDD:288883
STK35	NP_543026.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	32..176
		STKc_PDIK1L	201..529	CDD:270879	92/333 (28%)
		S_TKc	202..523	CDD:214567	92/333 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0595
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810