Protein Alignment Atg1 and Atg1

DIOPT Version :10

• Sequence 1: NP_001163433.1
• Gene: Atg1 / 39454
• FlyBaseID: FBgn0260945
• Length: 855
• Species: Drosophila melanogaster
• Sequence 2: XP_061510293.1
• Gene: Atg1 / 1270635
• VectorBaseID: AGAMI1_005780
• Length: 848
• Species: Anopheles gambiae
• Alignment Length: 906
• Identity: 523/906 - (57%)
• Similarity: 616/906 - (67%)
• Gaps: 113/906 - (12%)

  Fly     1 MNIVGEYEYSSKDMLGHGAFAVVYKGRHRKKHMPVAIKCITKKGQLKTQNLLGKEIKILKELTEL 65
            |.|||.|||:||:::||||||||:|||||:.|.|||||.||||...|:|:|||||||||:||:.|
Mosquito     1 MEIVGSYEYNSKEIIGHGAFAVVFKGRHREAHYPVAIKSITKKSLAKSQSLLGKEIKILQELSAL 65

  Fly    66 HHENVVALLDCKESQDCVSLVMEYCNGGDLADYLSVKGTLSEDTVRLFLVQLAGAMKALYTKGIV 130
            .|:|||.||.|.|....|.|||||||||||||||:|||||||||:||||.|||.||||||...:|
Mosquito    66 KHKNVVKLLACTEKDQNVFLVMEYCNGGDLADYLAVKGTLSEDTIRLFLGQLANAMKALYQADVV 130

  Fly   131 HRDLKPQNILLSHNYGKTLPAPSKITLKIADFGFARFLNEGAMAATLCGSPMYMAPEVIMSLQYD 195
            ||||||||||||||.||.||.|||||||||||||||||.:|.|||||||||||||||||||||||
Mosquito   131 HRDLKPQNILLSHNCGKGLPIPSKITLKIADFGFARFLQDGNMAATLCGSPMYMAPEVIMSLQYD 195

  Fly   196 SKADLWSLGTIVYQCLTGKAPFYAQTPNELKSYYEQNANLAPKIPSGVSPDLRDLLLCLLRRNSK 260
            :|||||||||||:|||||||||.|.||.|||.:||:|||||||||||.|.:|.|||:.|||||:|
Mosquito   196 AKADLWSLGTIVFQCLTGKAPFQAHTPQELKMFYERNANLAPKIPSGTSKELTDLLMGLLRRNAK 260

  Fly   261 DRISYESFFVHRFLQGKKAAVSPGEPSQAANLRRRVSKSGVLPVDMPPLGGTPPAKAKSP----- 320
            :|:::::||.|.|||..:......:|:..                  |.|.|  .|..||
Mosquito   261 ERMNFDTFFNHPFLQRAETPQGKNDPTPT------------------PFGAT--GKVSSPHQKTA 305

  Fly   321 ---LQQQ----------------------------LEQELKLVKLAEQQQKEREEQEAQEDENTV 354
               ||||                            :.|:|.|.:..:|||....:|:.|:.::.:
Mosquito   306 PITLQQQNQQKLHHHHHQQPSSQQTVQHHDQQQQHINQQLLLQQQQQQQQLHHAQQQKQQKQHHL 370

  Fly   355 SVVANPAICATITN----VGVLCDS----ENNSGSCSSHEDSDDFVLVPKNLPEDQRQGLAQVQA 411
            ..:|..   .|:.|    :..|.||    ..|..|.||.|:||||||||.|:|.|...|.:..::
Mosquito   371 HELAKK---QTVENNNVPIAELDDSVATISANHTSNSSPEESDDFVLVPNNIPVDPAHGGSYDKS 432

  Fly   412 QPASGGQRPQ-QQQNQSSPPRPSSLPISEPKPVPAPARRQVARPGPLTVATLGGQQIPRSQPISV 475
            :|.   :.|| ..|.|:||||||:||||||||||..||: |:|....|...  ...||||:||::
Mosquito   433 KPT---RVPQPMSQAQASPPRPSTLPISEPKPVPTAARK-VSRAQAQTPPK--NNSIPRSEPINM 491

  Fly   476 KQPRPDQRKSSVSSDINSISPPAVQFAIGTPPT--RMRSASGGSLSETPPPHAPSTWQVSPGHSQ 538
            |  |.:.|.|  :.||.|||||||||||||||:  |.||.|||||||||||  ||.|.||||..|
Mosquito   492 K--RSENRGS--NCDIRSISPPAVQFAIGTPPSCGRRRSTSGGSLSETPPP--PSCWTVSPGSHQ 550

  Fly   539 SPLRRSGNSSPVLPSAALTKLPTLGSPTMLVAPGSLGSIGSAGSGSENNNQH------HMLGPRA 597
            |||||||.||||: :.||:|||.|||||.|:            .|.||||.|      |.|..||
Mosquito   551 SPLRRSGTSSPVM-NNALSKLPALGSPTTLM------------GGVENNNHHHPHHHGHPLTARA 602

  Fly   598 FTLPELGATGGLHSLLDTGAGGGGEPHAFQAPELSEETLMDREHNETLSKLNFVLALTDCIQEVA 662
            ||||||||.|||.|.||... ....|..|.||||..|||:||:|||||:|||||:||||||.:||
Mosquito   603 FTLPELGAAGGLQSYLDDHT-IDDHPINFHAPELHAETLLDRDHNETLAKLNFVVALTDCILDVA 666

  Fly   663 DSRCAPLSTFMVAGSQSAAQAASADAQQIPPHAPEHCKRAERLVLLVRGLQLLSSGMNLASQQLS 727
            ||||||||:.|:           ||||.:|||.|||||||||||||||.|.|||:||||||.|:.
Mosquito   667 DSRCAPLSSMML-----------ADAQPVPPHQPEHCKRAERLVLLVRALHLLSAGMNLASAQIR 720

  Fly   728 NGQLKPSSNVKNALLTMNAKYRSMLFESKRLNGSGLLQKANAFNITADKILYDYALDMCQAAALD 792
            .|.||||::|||.|.||:|||||.|.|||:||.:||||:|||.|||||||::::||.|||.||:|
Mosquito   721 AGNLKPSNSVKNVLTTMHAKYRSTLIESKKLNSAGLLQRANASNITADKIIFEFALQMCQMAAVD 785

  Fly   793 ELLKNTKNCFERYNTAHILLHSLVQKCNHPQDKMMLNKYRDAVEKRLSILQQHGYIYMTDE 853
            ||......||.||.:|.||||.|.||..|||||::|:.|::||||||.||:..||||.|||
Mosquito   786 ELFNKPAECFPRYQSAQILLHWLAQKSKHPQDKILLSNYKEAVEKRLYILKGQGYIYTTDE 846

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atg1	NP_001163433.1	STKc_ULK1_2-like	15..273	CDD:271022	197/257 (77%)
		DUF3543	640..844	CDD:463451	133/203 (66%)
Atg1	XP_061510293.1	None