DRSC/TRiP Functional Genomics Resources

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Protein Alignment Atg1 and ulk3

DIOPT Version :9

Sequence 1:NP_001163433.1 Gene:Atg1 / 39454 FlyBaseID:FBgn0260945 Length:855 Species:Drosophila melanogaster
Sequence 2:NP_001082941.1 Gene:ulk3 / 100037316 ZFINID:ZDB-GENE-070410-33 Length:468 Species:Danio rerio


Alignment Length:432 Identity:141/432 - (32%)
Similarity:217/432 - (50%) Gaps:54/432 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly    13 DMLGHGAFAVVYKG-RHRKKHMPVAIKCITKKGQLKT--QNLLGKEIKILKELTELHHENVVALL 74
            :.||.|.:|.|||. |.......||:|.::||...|:  :||| .||:|||   .:.|.::|.|.
Zfish    18 ERLGSGTYATVYKAFRKTDSREAVAVKVVSKKSLNKSSMENLL-TEIEILK---TVRHPHIVQLK 78

  Fly    75 DCKESQDCVSLVMEYCNGGDLADYLSVKGTLSEDTVRLFLVQLAGAMKALYTKGIVHRDLKPQNI 139
            |.:...:.:.|::|:|:||||:.::..:..|.|...|..|.|:|.|::.|:.:.|.|.|||||||
Zfish    79 DFQWDSENIYLILEWCSGGDLSRFIRSRRILPERVARRCLQQIACALQFLHERNISHLDLKPQNI 143

  Fly   140 LLSHNYGKTLPAPSKITLKIADFGFARFLNEGAMAATLCGSPMYMAPEVIMSLQYDSKADLWSLG 204
            |||.|           .||::|||||::::.......|.|||:|||||::....||::.||||:|
Zfish   144 LLSGN-----------MLKLSDFGFAQYMSPWDEQHALRGSPLYMAPEIVCRKHYDARVDLWSVG 197

  Fly   205 TIVYQCLTGKAPFYAQTPNELKSYYEQNANLAPKIPSGVSPDLRDLLLCLLRRNSKDRISYESFF 269
            .|:|:.|.|:|||.:::..||:........:.....:|||.|.|||||.||.|:...||.:|.||
Zfish   198 VILYEALFGRAPFASRSFTELEEKIRSERPVELPAAAGVSRDCRDLLLRLLLRDPDRRICFEEFF 262

  Fly   270 VHRFLQGKKAAVSPGEPSQAANLRRRVSK------SGVLPVDMPPLGGTPPA-------KAKSPL 321
            :|.|:..:....:...|...|.:.:.|.|      |..|.:....|....||       :.|..|
Zfish   263 LHPFVDLEHMPSAESLPKAKALVLQAVQKDQDGDRSAALSLYCSALEQFVPAIHYETDRQRKEAL 327

  Fly   322 QQQLEQ------ELK-LVKLAEQQQKEREEQEAQEDENTVSVVA--NPAICATITNVGVLCDSEN 377
            :|::.|      ||| ||:    ...:...:||:...|.:..::  .|.:.|.: .|.....:..
Zfish   328 RQKVNQYVCRAEELKALVR----SDNKISFEEARSARNILIEMSRDQPRLLAAL-EVASTAVARE 387

  Fly   378 NSGSCSSHEDSDDFVLVPKNLPEDQRQGLAQVQAQPASGGQR 419
            .||:    ||.|...|..::|.|     :....|..|.|.:|
Zfish   388 ESGA----EDYDTLDLYQQSLGE-----MLLALAAEAQGRRR 420

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Atg1NP_001163433.1 S_TKc 9..274 CDD:214567 104/263 (40%)
STKc_ULK1_2-like 15..273 CDD:271022 104/260 (40%)
DUF3543 638..844 CDD:288883
ulk3NP_001082941.1 S_TKc 14..237 CDD:214567 87/233 (37%)
STKc_ULK3 18..266 CDD:271023 104/262 (40%)
MIT 276..350 CDD:294211 18/77 (23%)
MIT 371..442 CDD:294211 15/60 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1084750at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.920

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