DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42709 and Lrrc17

DIOPT Version :9

Sequence 1:	NP_001163434.1	Gene:	CG42709 / 39453	FlyBaseID:	FBgn0261674	Length:	458	Species:	Drosophila melanogaster
Sequence 2:	NP_083253.1	Gene:	Lrrc17 / 74511	MGIID:	1921761	Length:	443	Species:	Mus musculus

Alignment Length:	149	Identity:	41/149 - (27%)
Similarity:	63/149 - (42%)	Gaps:	12/149 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 ETAENRLMPQSSSTSTTTTFRPIFNIPRRSNHVLEPSCPRNCLCLEDFKFVQCANAHLTHVPLDM 120
            |..:.:|.|:...:......||..:.....|:|.            ..:.:.|....|..||.::
Mouse   216 EEEKEQLDPKPQVSGIPAVIRPEADSTLCHNYVF------------PIQTLDCKRKELKKVPSNI 268

  Fly   121 PKTAAIIDLSHNVIAELRPEDFANLSRAVEINLNHNLISSIDKDVFQGSERLKRLRLANNRLTKI 185
            |.....:|||.|.|.:|||::|.::....::||:.|.|..||...|.|...|:.|.|:||.|...
Mouse   269 PPDIVKLDLSSNKIRQLRPKEFEDVHELKKLNLSSNGIEFIDPAAFLGLIHLEELDLSNNSLQNF 333

  Fly   186 DPDTFAAAKELTLLDLSNN 204
            |.........|.||.|.:|
Mouse   334 DYGVLEDLYFLKLLWLRDN 352

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42709	NP_001163434.1	LRR_8	126..182	CDD:290566	22/55 (40%)
		leucine-rich repeat	128..147	CDD:275380	9/18 (50%)
		leucine-rich repeat	148..171	CDD:275380	8/22 (36%)
		LRR_RI	<150..225	CDD:238064	20/55 (36%)
		LRR_8	171..254	CDD:290566	12/34 (35%)
		leucine-rich repeat	172..195	CDD:275380	7/22 (32%)
		leucine-rich repeat	196..219	CDD:275380	5/9 (56%)
		leucine-rich repeat	220..243	CDD:275380
		leucine-rich repeat	244..268	CDD:275380
Lrrc17	NP_083253.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	20..48
		leucine-rich repeat	65..83	CDD:275380
		LRR 1	84..105
		leucine-rich repeat	85..108	CDD:275380
		LRR_8	86..143	CDD:290566
		LRR_4	107..148	CDD:289563
		LRR 2	108..129
		leucine-rich repeat	109..132	CDD:275380
		LRR 3	132..153
		leucine-rich repeat	133..156	CDD:275380
		leucine-rich repeat	157..207	CDD:275380
		TPKR_C2	165..>201	CDD:301599
		leucine-rich repeat	208..245	CDD:275380	5/28 (18%)
		leucine-rich repeat	251..271	CDD:275380	5/19 (26%)
		LRR_RI	<270..352	CDD:238064	28/81 (35%)
		LRR 4	271..292		9/20 (45%)
		leucine-rich repeat	272..295	CDD:275380	9/22 (41%)
		LRR_8	274..330	CDD:290566	22/55 (40%)
		LRR 5	295..316		7/20 (35%)
		LRR_4	296..334	CDD:289563	14/37 (38%)
		leucine-rich repeat	296..319	CDD:275380	8/22 (36%)
		LRR 6	319..342		7/22 (32%)
		leucine-rich repeat	320..343	CDD:275380	7/22 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000