DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG42709 and lrit2

DIOPT Version :9

Sequence 1:NP_001163434.1 Gene:CG42709 / 39453 FlyBaseID:FBgn0261674 Length:458 Species:Drosophila melanogaster
Sequence 2:NP_001018372.2 Gene:lrit2 / 553557 ZFINID:ZDB-GENE-050522-160 Length:561 Species:Danio rerio


Alignment Length:401 Identity:81/401 - (20%)
Similarity:134/401 - (33%) Gaps:122/401 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    89 LEPSCPRNCLCLED--FKFVQCANAHLTHVPLDMPKTAAIIDLSHNVIAELRPEDFANLSRAVEI 151
            :...|...|.|..|  .:.:.|....||.:|..:|:....|.:..:.::||....|:::.....:
Zfish    19 ISSECFPGCSCGTDRHGRSLTCMETALTGIPDGLPEDLTKIRIEKSQLSELPEAVFSHVKALKHL 83

  Fly   152 NLNHNLISSIDKDVFQGSERLKRLRLANNRLTKIDPDTFAAAKELTLLDLSNNTITQRLDGSFLN 216
            .||.|.|:.|:....:|...|..|||..|:|..:....|.....|.:|||.:|    |:|.    
Zfish    84 WLNFNDIAIINIKSLEGLANLTELRLQGNKLRSVPWTAFEETPNLKILDLKHN----RIDA---- 140

  Fly   217 QPDLVEFSCVNCSWTELPEQTFQNMSGLEVLRLNKNDFKQQINTKAFSPLTKIIKLKLPELEQQN 281
                            |||...:.:.||..|.|:.|.         .|.::|.:.|..|....:|
Zfish   141 ----------------LPEHALKFLPGLTYLDLSSNQ---------LSVISKDVFLNWPLYHSEN 180

  Fly   282 IEEL------------------CSLLTSIDTIS-------FLNYDISCY--EFVLGTPFNGSLIY 319
            ..|.                  |.|...|:.|.       .:|..::|.  |...|..|:     
Zfish   181 KHEKPSASNVVLALHDNPWLCDCRLGGFIEFIKSLTPPFILMNSYLTCSSPELKAGRFFH----- 240

  Fly   320 PTEPPLKGITNPPIVASITSTAKP----VTAT---PAPPRSANR--------------------- 356
              |..||....|.:.|.:.:...|    ||.|   .|.|.:..|                     
Zfish   241 --EVDLKTCVKPVVSAPVITITAPLGGNVTLTCSASARPEAVIRWIYALKMLRGFRDILSHVDED 303

  Fly   357 --------------NRGK--------MDNSTELVKAGILSSETSTSGVSVEPPAESQTN---QVQ 396
                          :||.        :.||:.::...:.|.|.|:|..|....|..:.|   .::
Zfish   304 TISSQLVIPSLHSADRGLYTCIANNFLGNSSVIISVDVKSPEGSSSHPSGPSAAIGEENVYIDIR 368

  Fly   397 ISQEAINTLLI 407
            |:::.:..:.|
Zfish   369 IAKQTVYGITI 379

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG42709NP_001163434.1 LRR_8 126..182 CDD:290566 15/55 (27%)
leucine-rich repeat 128..147 CDD:275380 3/18 (17%)
leucine-rich repeat 148..171 CDD:275380 6/22 (27%)
LRR_RI <150..225 CDD:238064 20/74 (27%)
LRR_8 171..254 CDD:290566 22/82 (27%)
leucine-rich repeat 172..195 CDD:275380 7/22 (32%)
leucine-rich repeat 196..219 CDD:275380 7/22 (32%)
leucine-rich repeat 220..243 CDD:275380 3/22 (14%)
leucine-rich repeat 244..268 CDD:275380 5/23 (22%)
lrit2NP_001018372.2 LRR 1 55..76 4/20 (20%)
LRR_8 56..114 CDD:290566 15/57 (26%)
leucine-rich repeat 56..79 CDD:275378 4/22 (18%)
LRR_4 78..118 CDD:289563 12/39 (31%)
LRR 2 79..102 6/22 (27%)
leucine-rich repeat 80..103 CDD:275378 6/22 (27%)
LRR_8 103..162 CDD:290566 22/91 (24%)
LRR_4 103..143 CDD:289563 15/63 (24%)
LRR 3 103..124 7/20 (35%)
leucine-rich repeat 104..127 CDD:275378 7/22 (32%)
LRR_4 126..166 CDD:289563 16/72 (22%)
LRR 4 127..150 10/46 (22%)
leucine-rich repeat 128..151 CDD:275378 10/46 (22%)
LRR 5 151..172 7/29 (24%)
leucine-rich repeat 152..165 CDD:275378 5/21 (24%)
leucine-rich repeat 189..201 CDD:275378 0/11 (0%)
TPKR_C2 197..240 CDD:301599 8/42 (19%)
IG_like 258..341 CDD:214653 11/82 (13%)
IGc2 264..328 CDD:197706 8/63 (13%)
fn3 366..438 CDD:278470 2/14 (14%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 507..561
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
00.000

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