DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42709 and Lrrc17

DIOPT Version :9

Sequence 1:	NP_001163434.1	Gene:	CG42709 / 39453	FlyBaseID:	FBgn0261674	Length:	458	Species:	Drosophila melanogaster
Sequence 2:	NP_001020326.1	Gene:	Lrrc17 / 502715	RGDID:	1560165	Length:	446	Species:	Rattus norvegicus

Alignment Length:	149	Identity:	41/149 - (27%)
Similarity:	64/149 - (42%)	Gaps:	12/149 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 ETAENRLMPQSSSTSTTTTFRPIFNIPRRSNHVLEPSCPRNCLCLEDFKFVQCANAHLTHVPLDM 120
            |..:.||.|....:......||..:.....|:|.            ..:.:.|....|..||.::
  Rat   219 EEEKERLDPIPQVSGVPAVIRPEADSTLCHNYVF------------PIQTLDCKRKELKKVPNNI 271

  Fly   121 PKTAAIIDLSHNVIAELRPEDFANLSRAVEINLNHNLISSIDKDVFQGSERLKRLRLANNRLTKI 185
            |.....:|||:|.|::|||::|.::....::||:.|.:..||...|.|...|:.|.|:||.|...
  Rat   272 PPNIVKLDLSYNKISQLRPKEFEDVHELKKLNLSSNGLEFIDPAAFLGLIHLEELDLSNNSLQSF 336

  Fly   186 DPDTFAAAKELTLLDLSNN 204
            |.........|.||.|.:|
  Rat   337 DYGVLEDLYFLKLLWLRDN 355

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42709	NP_001163434.1	LRR_8	126..182	CDD:290566	21/55 (38%)
		leucine-rich repeat	128..147	CDD:275380	9/18 (50%)
		leucine-rich repeat	148..171	CDD:275380	7/22 (32%)
		LRR_RI	<150..225	CDD:238064	19/55 (35%)
		LRR_8	171..254	CDD:290566	12/34 (35%)
		leucine-rich repeat	172..195	CDD:275380	7/22 (32%)
		leucine-rich repeat	196..219	CDD:275380	5/9 (56%)
		leucine-rich repeat	220..243	CDD:275380
		leucine-rich repeat	244..268	CDD:275380
Lrrc17	NP_001020326.1	leucine-rich repeat	68..86	CDD:275380
		LRR_8	89..146	CDD:290566
		leucine-rich repeat	89..111	CDD:275380
		LRR_4	110..151	CDD:289563
		leucine-rich repeat	112..135	CDD:275380
		leucine-rich repeat	136..159	CDD:275380
		leucine-rich repeat	160..210	CDD:275380
		TPKR_C2	168..>204	CDD:301599
		leucine-rich repeat	211..274	CDD:275380	13/66 (20%)
		LRR_8	273..333	CDD:290566	21/59 (36%)
		LRR_4	273..314	CDD:289563	13/40 (33%)
		leucine-rich repeat	275..298	CDD:275380	9/22 (41%)
		LRR_4	299..337	CDD:289563	13/37 (35%)
		leucine-rich repeat	299..322	CDD:275380	7/22 (32%)
		leucine-rich repeat	323..346	CDD:275380	7/22 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000