DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG42709 and LRIT2

DIOPT Version :9

Sequence 1:NP_001163434.1 Gene:CG42709 / 39453 FlyBaseID:FBgn0261674 Length:458 Species:Drosophila melanogaster
Sequence 2:NP_001271152.1 Gene:LRIT2 / 340745 HGNCID:23443 Length:560 Species:Homo sapiens


Alignment Length:288 Identity:63/288 - (21%)
Similarity:105/288 - (36%) Gaps:63/288 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly    87 HVLEPSCPRNCLCLEDF--KFVQCANAHLTHVPLDMPKTAAIIDLSHNVIAELRPEDFANLSRAV 149
            |..:|.|...|.|.|:.  :.:||.:..|..:|.::.:....:.:.::.:.|:....|.|:|...
Human    18 HAAQPFCLPGCTCSEESFGRTLQCTSVSLGKIPGNLSEEFKQVRIENSPLFEMPQGSFINMSTLE 82

  Fly   150 EINLNHNLISSIDKDVFQGSERLKRLRLANNRLTKIDPDTFAAAKELTLLDLSNNTITQRLDGSF 214
            .:.||.|.||.|.....:....|:.|||..|:|..:....|.|...|.:|||..|.|        
Human    83 YLWLNFNNISVIHLGALEHLPELRELRLEGNKLCSVPWTAFRATPLLRVLDLKRNKI-------- 139

  Fly   215 LNQPDLVEFSCVNCSWTELPEQTFQNMSGLEVLRLNKNDFKQQINTKAFSPLTKIIKLKLPELEQ 279
                            ..|||...|.:..|..|.|:.|.. ..::...|.......|.:.|:...
Human   140 ----------------DALPELALQFLVSLTYLDLSSNRL-TVVSKSVFLNWPAYQKCRQPDCGA 187

  Fly   280 QNIEEL------------C---SLLTSIDTISFLNYDISCYEFVLGTPFN--GSLIYPTEPPLKG 327
            :.:..|            |   .|:..:.:|:.....::.|....| |.:  |.|.:.||     
Human   188 EILSSLVVALHDNPWVCDCRLRGLVQFVKSITLPVILVNSYLICQG-PLSKAGQLFHETE----- 246

  Fly   328 ITNPPIVASITSTAKPVTATPAPPRSAN 355
                     :::..||..:||    |||
Human   247 ---------LSACMKPQISTP----SAN 261

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG42709NP_001163434.1 LRR_8 126..182 CDD:290566 15/55 (27%)
leucine-rich repeat 128..147 CDD:275380 3/18 (17%)
leucine-rich repeat 148..171 CDD:275380 6/22 (27%)
LRR_RI <150..225 CDD:238064 20/74 (27%)
LRR_8 171..254 CDD:290566 22/82 (27%)
leucine-rich repeat 172..195 CDD:275380 8/22 (36%)
leucine-rich repeat 196..219 CDD:275380 6/22 (27%)
leucine-rich repeat 220..243 CDD:275380 4/22 (18%)
leucine-rich repeat 244..268 CDD:275380 5/23 (22%)
LRIT2NP_001271152.1 leucine-rich repeat 37..55 CDD:275380 4/17 (24%)
leucine-rich repeat 58..80 CDD:275378 3/21 (14%)
LRR_8 60..115 CDD:290566 15/54 (28%)
LRR_RI <75..164 CDD:238064 31/113 (27%)
LRR 1 80..103 6/22 (27%)
LRR_4 81..119 CDD:289563 12/37 (32%)
leucine-rich repeat 81..104 CDD:275378 6/22 (27%)
LRR_8 103..163 CDD:290566 22/83 (27%)
LRR 2 104..125 7/20 (35%)
leucine-rich repeat 105..128 CDD:275378 8/22 (36%)
LRR 3 128..149 9/44 (20%)
leucine-rich repeat 129..152 CDD:275378 10/46 (22%)
LRR 4 152..173 5/21 (24%)
leucine-rich repeat 153..164 CDD:275378 4/11 (36%)
leucine-rich repeat 193..204 CDD:275378 1/10 (10%)
TPKR_C2 200..243 CDD:301599 8/43 (19%)
I-set 253..354 CDD:254352 6/13 (46%)
IGc2 267..344 CDD:197706
FN3 377..440 CDD:214495
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 518..560
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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