DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG42709 and Rtn4rl2

DIOPT Version :9

Sequence 1:NP_001163434.1 Gene:CG42709 / 39453 FlyBaseID:FBgn0261674 Length:458 Species:Drosophila melanogaster
Sequence 2:NP_852045.1 Gene:Rtn4rl2 / 311169 RGDID:727797 Length:420 Species:Rattus norvegicus


Alignment Length:405 Identity:91/405 - (22%)
Similarity:147/405 - (36%) Gaps:99/405 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly    91 PSCPRNCLCLEDFKFVQCANAHLTHVPLDMPKTAAIIDLSHNVIAELRPEDFA-----------N 144
            ||||..|.|......|.|...:.:.|||.:|.:...:.|.:|:|..|||..|.           |
  Rat    29 PSCPMLCTCYSSPPTVSCQANNFSSVPLSLPPSTQRLFLQNNLIRSLRPGTFGPNLLTLWLFSNN 93

  Fly   145 LSRAV-----------EINLNHNL-ISSIDKDVFQGSERLKRLRLANNRLTKIDPDTFAAAKELT 197
            ||...           |::|..|. :.|::.|.|||.|||:.|.|...:|:.:..:.|.....|.
  Rat    94 LSTIYPGTFRHLQALEELDLGDNRHLRSLEPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSLQ 158

  Fly   198 LLDLSNNTITQRLDGSFLNQPDLVEFSCVNCSWTELPEQTFQNMSGLEVLRLNKNDFKQQINTKA 262
            .|.|..|::....|..|.:..:|............|.|..|:.:..|:.|.|:.|.. |.::..|
  Rat   159 YLYLQENSLLHLQDDLFADLANLSHLFLHGNRLRLLTEHVFRGLGSLDRLLLHGNRL-QGVHRAA 222

  Fly   263 FSPLTKIIKLKLPELEQQNIEELCSL----LTSIDTISFLNYDIS-----CYEFVLGTPF----- 313
            |..|:::..|.|..      ..|.||    |..:..:.||..:.:     |....|...|     
  Rat   223 FHGLSRLTILYLFN------NSLASLPGEALADLPALEFLRLNANPWACDCRARPLWAWFQRARV 281

  Fly   314 -NGSLIYPTEPPLKGITNPPIVASITSTAKPVTATPAPPRSANRNRGKMDNSTE-----LVKAGI 372
             :..:...|.|..:|..    :.::..|.......|.|.|..:|.||   ||:.     :.:||.
  Rat   282 SSSDVTCATPPERQGRD----LRTLRDTDFQACPPPTPTRPGSRARG---NSSSNHLYGVAEAGA 339

  Fly   373 LSSETST---------------------------------------SGVSVEPPAESQTNQVQIS 398
            ..::.||                                       .|.:.:.||:|:.   .:.
  Rat   340 PPADPSTLYRDLPAEDSRGRQGGDAPTEDDYWGGYGGEDQRGEQTCPGAACQAPADSRG---PVL 401

  Fly   399 QEAINTLLICIMVLA 413
            ...:.|.|:|:::||
  Rat   402 SAGLRTPLLCLLLLA 416

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG42709NP_001163434.1 LRR_8 126..182 CDD:290566 23/78 (29%)
leucine-rich repeat 128..147 CDD:275380 9/29 (31%)
leucine-rich repeat 148..171 CDD:275380 8/34 (24%)
LRR_RI <150..225 CDD:238064 22/75 (29%)
LRR_8 171..254 CDD:290566 20/82 (24%)
leucine-rich repeat 172..195 CDD:275380 5/22 (23%)
leucine-rich repeat 196..219 CDD:275380 6/22 (27%)
leucine-rich repeat 220..243 CDD:275380 4/22 (18%)
leucine-rich repeat 244..268 CDD:275380 8/23 (35%)
Rtn4rl2NP_852045.1 LRR_8 60..117 CDD:290566 12/56 (21%)
LRR 1 61..82 7/20 (35%)
leucine-rich repeat 62..83 CDD:275380 7/20 (35%)
LRR 2 83..104 3/20 (15%)
leucine-rich repeat 84..107 CDD:275380 3/22 (14%)
LRR_RI 103..>261 CDD:238064 41/164 (25%)
LRR 3 107..129 6/21 (29%)
LRR_8 108..167 CDD:290566 19/58 (33%)
leucine-rich repeat 108..132 CDD:275380 8/23 (35%)
LRR 4 132..153 6/20 (30%)
leucine-rich repeat 133..156 CDD:275380 5/22 (23%)
LRR_8 156..215 CDD:290566 14/58 (24%)
LRR 5 156..177 6/20 (30%)
leucine-rich repeat 157..180 CDD:275380 6/22 (27%)
LRR 6 180..201 4/20 (20%)
leucine-rich repeat 181..204 CDD:275380 4/22 (18%)
LRR_8 204..262 CDD:290566 16/64 (25%)
LRR 7 204..225 7/21 (33%)
leucine-rich repeat 205..228 CDD:275380 8/23 (35%)
LRR 8 228..249 6/26 (23%)
leucine-rich repeat 229..252 CDD:275380 6/28 (21%)
TPKR_C2 261..311 CDD:301599 7/53 (13%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 286..390 17/110 (15%)
Important for interaction with MAG. /evidence=ECO:0000269|PubMed:19420245 315..327 6/14 (43%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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