DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42709 and Lrrc3

DIOPT Version :9

Sequence 1:	NP_001163434.1	Gene:	CG42709 / 39453	FlyBaseID:	FBgn0261674	Length:	458	Species:	Drosophila melanogaster
Sequence 2:	NP_660134.1	Gene:	Lrrc3 / 237387	MGIID:	2447899	Length:	257	Species:	Mus musculus

Alignment Length:	190	Identity:	52/190 - (27%)
Similarity:	82/190 - (43%)	Gaps:	37/190 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 GEESPETAENRLMPQSSSTSTTTTFRPIFNIPRRSNHVLEPSCPRNCLCLE--DFKFVQCANAHL 113
            |.:||...   |.|...|     .|..:|.:.      |..|||:.|.|.:  ....|.|::..|
Mouse     5 GRQSPSAT---LAPSQGS-----CFFILFCLR------LGASCPQACQCPDHAGAVAVHCSSRGL 55

  Fly   114 THVPLDMPKTAAIIDLSHNVIAELRPEDFANLSRAVEINLNHNLISSIDKDVFQG-SERLKRLRL 177
            ..:|.|:|....::.|..|.|:.:....|.:|.:..|::|:||.|.:|....|.| :..|:.|.|
Mouse    56 QEIPRDIPADTVLLKLDANRISRVPNGAFQHLPQLRELDLSHNAIEAIGPAAFSGLAGGLRLLDL 120

  Fly   178 ANNRLTKIDPDTFAAAKELTLLDLSNNTI-----------TQRLDGSFLNQPDLV-EFSC 225
            ::||:.:|..|  |..|....:.||:|.:           ..:||      ||.| |.:|
Mouse   121 SHNRIRRIPKD--ALGKLSAKIRLSHNPLHCECALQEALWELKLD------PDSVDEIAC 172

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42709	NP_001163434.1	LRR_8	126..182	CDD:290566	17/56 (30%)
		leucine-rich repeat	128..147	CDD:275380	5/18 (28%)
		leucine-rich repeat	148..171	CDD:275380	8/23 (35%)
		LRR_RI	<150..225	CDD:238064	26/87 (30%)
		LRR_8	171..254	CDD:290566	19/67 (28%)
		leucine-rich repeat	172..195	CDD:275380	8/22 (36%)
		leucine-rich repeat	196..219	CDD:275380	5/33 (15%)
		leucine-rich repeat	220..243	CDD:275380	3/7 (43%)
		leucine-rich repeat	244..268	CDD:275380
Lrrc3	NP_660134.1	LRRNT	33..68	CDD:214470	10/34 (29%)
		leucine-rich repeat	48..68	CDD:275378	6/19 (32%)
		LRR 1	65..86		4/20 (20%)
		LRR_8	69..125	CDD:290566	17/55 (31%)
		LRR_4	69..105	CDD:289563	11/35 (31%)
		leucine-rich repeat	69..89	CDD:275378	5/19 (26%)
		LRR_4	88..129	CDD:289563	13/40 (33%)
		LRR 2	89..110		7/20 (35%)
		leucine-rich repeat	90..114	CDD:275378	8/23 (35%)
		LRR 3	114..135		8/22 (36%)
		leucine-rich repeat	115..138	CDD:275378	9/24 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	2	1.870