DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG42709 and Lrtm2

DIOPT Version :9

Sequence 1:NP_001163434.1 Gene:CG42709 / 39453 FlyBaseID:FBgn0261674 Length:458 Species:Drosophila melanogaster
Sequence 2:NP_001165678.1 Gene:Lrtm2 / 211187 MGIID:2141485 Length:370 Species:Mus musculus


Alignment Length:347 Identity:81/347 - (23%)
Similarity:134/347 - (38%) Gaps:75/347 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly    91 PSCPRNCLCLEDFKFVQCANAHLTHVPLDMPKTAAIIDLSHNVIAELRPEDFANLSRAVEINLNH 155
            |:||.:|.|......|.|:...||.||.|:|.....:.|.:|.::.|....|||||....::|::
Mouse    37 PACPFSCTCDSRSLEVDCSGLGLTTVPPDVPAATQSLLLLNNKLSALPSWAFANLSNLQRLDLSN 101

  Fly   156 NLISSIDKDVFQGSERLKRLRLANNRLTKIDPDTFAAAKELTLLDLSNNTITQRLDGSFLNQPDL 220
            |.:..:.:.:|:....|..|:|.||.:..:|.|....:..|..||||.|.:.|...|.|.....|
Mouse   102 NFLDQLPRSIFEDLVNLTELQLRNNSIRTLDRDLLQHSPLLRHLDLSINGLAQLPPGLFDGLLAL 166

  Fly   221 VEFSCVNCSWTELPEQTFQNMSGLEVLRLNKNDFKQQINTKAFSPLTKIIKLKLPELEQQNIEEL 285
            ...|..:.....|...||:.::.|::|::..|.::...|.:.|....:....:...|:|.    .
Mouse   167 RSLSLRSNRLQSLDRLTFEPLASLQLLQVGDNPWECDCNLREFKHWLEWFSYRGGRLDQL----A 227

  Fly   286 CSL---LTSID----TISFLNYDISCYEFVLGTPFNGSLIYPTEPPLKGITNPPIVASITSTAKP 343
            |:|   |...|    .:...||   |.:                  |:...|.   |.:.:...|
Mouse   228 CTLPKELRGKDMRAVPMEMFNY---CSQ------------------LEDENNS---AGLDAPGPP 268

  Fly   344 VT-ATPAPPRSANRNRGKMDNSTELVKAGILSSETSTSGVSVEP------PAESQTNQVQISQEA 401
            .| |:|.||:                         ...|...||      |.:.:...|.: :.|
Mouse   269 CTKASPEPPK-------------------------PKPGAEPEPEPSTACPQKQRYRPVSV-RRA 307

  Fly   402 INTLLICIMVLAVIGIVIGLIC 423
            |.|::|.       |:|.|::|
Mouse   308 IGTVIIA-------GVVCGIVC 322

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG42709NP_001163434.1 LRR_8 126..182 CDD:290566 16/55 (29%)
leucine-rich repeat 128..147 CDD:275380 7/18 (39%)
leucine-rich repeat 148..171 CDD:275380 3/22 (14%)
LRR_RI <150..225 CDD:238064 20/74 (27%)
LRR_8 171..254 CDD:290566 24/82 (29%)
leucine-rich repeat 172..195 CDD:275380 7/22 (32%)
leucine-rich repeat 196..219 CDD:275380 9/22 (41%)
leucine-rich repeat 220..243 CDD:275380 5/22 (23%)
leucine-rich repeat 244..268 CDD:275380 5/23 (22%)
Lrtm2NP_001165678.1 LRRNT 38..67 CDD:396168 11/28 (39%)
leucine-rich repeat 51..93 CDD:275378 15/41 (37%)
LRR 1 69..90 4/20 (20%)
LRR_8 92..152 CDD:404697 17/59 (29%)
LRR 2 93..114 3/20 (15%)
leucine-rich repeat 94..117 CDD:275378 3/22 (14%)
LRR 3 117..138 7/20 (35%)
leucine-rich repeat 118..141 CDD:275378 7/22 (32%)
LRR 4 141..162 9/20 (45%)
leucine-rich repeat 142..189 CDD:275378 14/46 (30%)
LRR 5 165..186 5/20 (25%)
leucine-rich repeat 166..186 CDD:275380 5/19 (26%)
leucine-rich repeat 190..202 CDD:275378 3/11 (27%)
TPKR_C2 198..247 CDD:417692 9/52 (17%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 260..297 11/61 (18%)
Herpes_glycop_D <261..335 CDD:421518 19/95 (20%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 351..370
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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