DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42709 and prelp

DIOPT Version :9

Sequence 1:	NP_001163434.1	Gene:	CG42709 / 39453	FlyBaseID:	FBgn0261674	Length:	458	Species:	Drosophila melanogaster
Sequence 2:	NP_001096208.1	Gene:	prelp / 100124759	XenbaseID:	XB-GENE-964437	Length:	374	Species:	Xenopus tropicalis

Alignment Length:	312	Identity:	79/312 - (25%)
Similarity:	121/312 - (38%)	Gaps:	99/312 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    91 PSCPRNCLCLEDF-KFVQCANAHLTHVPLDMPKTAAIIDLSHNVIAELRPEDFANLSRAVEINLN 154
            |.|||.|.|..|| ..:.|.:.:|..|| .:|..|..:.|.:|.|.:|:.|.|.|.:....|||:
Frog    63 PDCPRECFCPPDFPSTIYCDSRNLRKVP-TLPNRARYVYLQNNFIDDLQEESFKNATEIQWINLD 126

  Fly   155 HNLISSIDKDVFQG---------------------SERLKRLRLANNRLTKIDPDTFAAAKELTL 198
            :|.|..::|.:.:.                     ..||::|||:.|:::||....|:..:.|.|
Frog   127 NNRIKKVEKKILEKMNNLTYLYLEKNQLKEMPSYLPSRLEQLRLSRNQISKIPSGVFSKMEHLVL 191

  Fly   199 LDLSNNTITQRLDGSF-------------LN--------QPDLVEFSCVNCSW------TELPEQ 236
            |||.:|.::   ||.|             ||        .|..|..| ||..:      .::|..
Frog   192 LDLHHNKLS---DGGFSKNTFKGLKNLIQLNLAHNILRKMPQAVPES-VNQLFLDRNNIEDIPAD 252

  Fly   237 TFQNMSGLEVLRLNKNDF------KQQINTK-------AFSPLTKI--IKLKLPEL-------EQ 279
            .|:.:..|..||||.|..      |...|..       |.:.||.:  |.:||..|       |:
Frog   253 YFKELPNLAFLRLNYNQLSDKGLPKNLFNVSSLLVLQLAHNKLTVVPPISIKLEHLYLNDNIIEK 317

  Fly   280 QNIEELCSL-----------LTSIDTISFLNYD------------ISCYEFV 308
            .|..|:|..           |:|:..:.:|..|            |.|:..:
Frog   318 INGTEICPAPLVPFDFSSRDLSSVPRLRYLRLDGNQLKPPIPLDVIMCFRLL 369

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42709	NP_001163434.1	LRR_8	126..182	CDD:290566	19/76 (25%)
		leucine-rich repeat	128..147	CDD:275380	7/18 (39%)
		leucine-rich repeat	148..171	CDD:275380	6/43 (14%)
		LRR_RI	<150..225	CDD:238064	28/116 (24%)
		LRR_8	171..254	CDD:290566	33/109 (30%)
		leucine-rich repeat	172..195	CDD:275380	8/22 (36%)
		leucine-rich repeat	196..219	CDD:275380	11/43 (26%)
		leucine-rich repeat	220..243	CDD:275380	6/28 (21%)
		leucine-rich repeat	244..268	CDD:275380	10/36 (28%)
prelp	NP_001096208.1	LRRNT	64..98	CDD:214470	13/34 (38%)
		leucine-rich repeat	96..119	CDD:275380	8/22 (36%)
		leucine-rich repeat	120..143	CDD:275380	6/22 (27%)
		PRK15370	<125..>353	CDD:185268	54/231 (23%)
		leucine-rich repeat	144..164	CDD:275380	0/19 (0%)
		leucine-rich repeat	165..188	CDD:275380	8/22 (36%)
		leucine-rich repeat	189..214	CDD:275380	9/27 (33%)
		leucine-rich repeat	215..235	CDD:275380	4/19 (21%)
		leucine-rich repeat	236..259	CDD:275380	4/22 (18%)
		leucine-rich repeat	260..284	CDD:275380	8/23 (35%)
		leucine-rich repeat	285..304	CDD:275380	4/18 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	66	1.000	Inparanoid score	I5177
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.960