Protein Alignment Vps13D and Vps13a

DIOPT Version :9

• Sequence 1: NP_729825.2
• Gene: Vps13D / 39448
• FlyBaseID: FBgn0052113
• Length: 3919
• Species: Drosophila melanogaster
• Sequence 2: NP_766616.2
• Gene: Vps13a / 271564
• MGIID: 2444304
• Length: 3166
• Species: Mus musculus
• Alignment Length: 4166
• Identity: 758/4166 - (18%)
• Similarity: 1388/4166 - (33%)
• Gaps: 1467/4166 - (35%)

  Fly     1 MLRDLITWVLNTYLGKYLENLNSAQLSVALLSGEVELENIPIRKDALRSFNLPVEVTAGSIRKIK 65
            :...::..|||.:||.|:.||:.:|||:.:..|.|.|:|:.|:::||...::|.:|..|.|..:|
Mouse     2 VFESVVVEVLNRFLGDYVVNLDESQLSLGIWKGAVALKNLVIKENALHELDVPFKVKVGHIGSLK 66

  Fly    66 LQIPVRQFRTSPWCISIEGLFCIICPKNLDNWDYEKEKLQDLEYKLAVLDTAEAG----WRSEKG 126
            |:||.:...|.|....:|.:|.:|.|.:...:|..||:.|.:|.|...|...|..    :..||.
Mouse    67 LKIPWKNLYTQPVEAVLEEIFLLIVPSSRIQYDPIKEEKQLMETKQQELKRIEKAKQKVFDKEKP 131

  Fly   127 KQMESYYFSSYNNWLKYGTNMATNIIDNIELKISDVHFRFEDIVDTGKSKICTGIKIGSLTAQSC 191
            ::.:...|:.         .:.|.||.|::::||.:|.|:||.:..|...:..||.:.:::.|:.
Mouse   132 REEKQDTFTE---------KLVTQIIQNLQVQISSIHIRYEDDITNGDKPLSFGISLQNISLQTT 187

  Fly   192 DCDWTNGSYKMNNNEMNYKLVELKELSVYWDLLHEDIKCQSYS-----------NQEILEKMHST 245
            |..|....:. |..::..||:.|..|..||::..|......|.           |:.|:.:
Mouse   188 DQYWIPCLHD-NTEKLVRKLIRLDNLFAYWNVNSEMFYLNDYDESLKALKNGIVNENIVPE---- 247

  Fly   246 CELRSHNFIIKPICATARWKRDKCQQVIRTKD----KPRVSCELLVPEVVIDISKVQRLQMLDKL 306
                .::|:.:||.|:|:      .|:.|..|    .|:::..:.:..:.|:.:|.|...:::.|
Mouse   248 ----GYDFVFRPISASAK------LQMNRRSDFDFSDPKINLAVDLHTIAIEFNKPQYFSLMELL 302

  Fly   307 SEIRQVKEVRQYRLKRPTCTVESNPIAWWKYA-------TIC-------------HGFDFKKNEE 351
            ..|..:.:.:.||..:|:..:..:...||.||       .:|             |.:..|
Mouse   303 ESIDMMTQNQPYRKFKPSVPLHLHAKEWWAYAIHSILEVNVCPSLRMWSWEHIRNHRYKMK---- 363

  Fly   352 KWLMLKENLRYMLLYKSIILN--PNENLSAADKEFKAYIESDRKISDLTIMR-------RICFEK 407
                     ||...||..:.:  |:..:..:.:|    :|....:.::||.|       :....|
Mouse   364 ---------RYREFYKKKLTSKKPSPEILMSLEE----LEKTLDVFNITIARQQAEVEAKKAGYK 415

  Fly   408 VFTKGFAFESQNEQGKNMLFHWFPNWMGW-YANSPSTPNNEQDESLKHLEDDILVALENSLQ--- 468
            ::.:|......|           ..|.|| :..|.|..|.:||.....|| ::|...|.||.
Mouse   416 IYKEGVKDPEDN-----------AGWFGWLWTWSESNANQQQDVKPGILE-EMLTPEEKSLLYEA 468

  Fly   469 -NSSDLKSDAVFGHFSIKLLKGLVILQTEDKLNDGRNKSMEMQFNNFSAYLQLSPQLTSYTV-GI 531
             ..|:...|..... :.:.||..|.|         ::.|:.::.|:      ..|:|.:..| |:
Mouse   469 IGYSETAVDPTLPK-TFEALKFFVHL---------KSMSIVLRENH------QKPELLNVVVEGL 517

  Fly   532 SLQEVY------LIDKTSSDTMHNYLIKPQTGNTATPNQLVKN---AALQEDILFQLQYENCNHL 587
            |...|.      :..:|..|:.|         .|..|:...|.   ::|.:..|.|:.:| .|.|
Mouse   518 STSVVQRPGAQAIKFETKIDSFH---------ITGLPDDFKKPHLLSSLDDTSLLQITFE-INPL 572

  Fly   588 R----FQLNIKSKGLDLIYNEDAIQWLLDFLADSNSFKYSPRNRVAKKTDFMKNWNEMFSGNEVN 648
            .    .:..|:::.|::||:...:..:::|      |:......:|:.|.......|.|......
Mouse   573 NETVAQRCTIEAEPLEIIYDARTVNSIVEF------FRPPKDVHLAQLTSVTLTKLEEFRAKTAT 631

  Fly   649 RKIWMFE--------IEIFAPRIIFLE--NYKVSNSLMVLLDFGKLEMRKMEVKRVIPVIESAVT 703
            ..:::.|        |.:.|..:|..:  |:..:::|: |||.|.|   |:..||
Mouse   632 GLLYVIETQKVLDLRINVKASYVIVPQYGNFSPTSNLL-LLDLGHL---KVSSKR---------- 682

  Fly   704 ENTSDDDETYLTPCSTPPASEKSGSESPTLLENPKTESFLNKNVQLEYVLHNKIYDKYLINFTNL 768
                    ..|.|...|  ||.|                      ||.::| :.||.:.|..|::
Mouse   683 --------RSLLPDVRP--SEAS----------------------LEDIMH-RAYDSFDIQLTSI 714

  Fly   769 QVLVCKYEERWQACLKTS-SNFHLIDKFNINLTLEQRNIFTVDPEYPSFMLFGTCPTILIHGNEE 832
            |:|..:..:.|:...|.: |..|::...::|:.|.:..:| :|.:.|.|.:.|..|.:.:..::
Mouse   715 QLLYSRVGDNWKEARKLNVSTQHILIPMHVNVELSKAMVF-MDIKMPKFKISGKLPLVSLRISD- 777

  Fly   833 LINNCCNIMKPIIKASKEMENIYRGGNTIYASERIKNLAEDDRSRVVIEFVMDQLVIEMQSTERS 897
                            |:::.|
Mouse   778 ----------------KKLQGI------------------------------------------- 783

  Fly   898 IAELQIIGARAGLTKEPHETNISMSVHGLLLVDAIQSFGPDFELLVASHRHVGMDSLSGSLKHSA 962
               ::::|:   :.|....|::|...         :||......|..||
Mouse   784 ---MELLGS---IPKPEPVTDVSAPA---------RSFQIQASALPVSH---------------- 817

  Fly   963 IVSPTSPGSPNFFDRATSPHMITKAVQNIKMGDRSTEFCDDEDSTALISVDIKIVPPNESNSMQL 1027
                            .|..:|....|.:...|...||.|...|           |..|...:..
Mouse   818 ----------------ISQKLIPLLEQPVTEDDSEEEFFDAPCS-----------PLEECPQVSC 855

  Fly  1028 HTTSITFNSLDIIANQDTIIEILNFAKRTLLAQNIFPSESPESPKEATEAPVDVVDQVDHKSHNE 1092
            .........|.   .:|.::.::....|..:|                                |
Mouse   856 RDKCTRQKKLQ---KKDCVMNLIQLRMRFEVA--------------------------------E 885

  Fly  1093 IFFDFFRLNILLLYTIKRDKFNVGRKVGTVTLTEAKINASFQSDLSIIGSLGGIQVIDITSEAFC 1157
            :...|:.|                  ||...|...::.|
Mouse   886 VSIQFYHL------------------VGDCELPVLEMGA-------------------------- 906

  Fly  1158 HPRILSVGRDQILRASDTNKQTVLSQLSNEIYSNNYNEETKSDESDAISFQSHWSDKTTCTFQMR 1222
                |.:|.:...|..|......|.:|
Mouse   907 ----LGLGTEAEFRTFDLKGSAFLKEL-------------------------------------- 929

  Fly  1223 MASASYTHCPRFLRDVNACITYFKRSLREFATSIGNKATDMAKEFVQQVRAVEQIGPVYPQRNRQ 1287
                 :..||.:|.:                    ||.                  |||
Mouse   930 -----WLKCPEYLDE--------------------NKK------------------PVY------ 945

  Fly  1288 DNWLDIIISSPIIILPISNTSTNVLIANLGKISCSNAVKCDSDEFNESYTIEIKNTYVYSLNIDE 1352
                        :|..:.||..::|.....|:              |.....:.:||
Mouse   946 ------------LITTLDNTMEDLLTLEFMKV--------------EKNAPNLNSTY-------- 976

  Fly  1353 GEYSFNVHPAKNKDAIPILHDTAITLQLYAGYSDDNDEDKQLNRFSIKGSMVEALKVSLNRKQYE 1417
                                                            .::::.:||:.:.....
Mouse   977 ------------------------------------------------NNVLQLIKVNFSSLDIH 993

  Fly  1418 LLLESIRYATNFSNEVLNE---------SDELDQNGDI-------EPTANIDAESIISTTIQFSV 1466
            |..|::....|:.|.:|.|         :.|.:..|||       .||    .|.||:..:...:
Mouse   994 LHTEALLNTMNYLNNILPELREKSASVSAAEPEDKGDIIKKLALKLPT----NEDIITLQLLAEL 1054

  Fly  1467 PVFQINLQNEYHNDLINLTFKNFNVKHIS-KGFDKDVEVVLKSVLMEDLKSDLTSPFRNMVTSVD 1530
            ...||.:|::..           |:..|. :|.|.:       ::|:.|.:::.:..||::.
Mouse  1055 SCLQIFIQDQKQ-----------NISEIKIEGLDSE-------MIMKPLVTEINAKLRNIIV--- 1098

  Fly  1531 LEQKIKKNEMTSSSCPDLPSYCNSLKNRSSSVPSCFYNHMQVKVFGGDQKYTSSNKNELGKKKES 1595
                                                                          .:|
Mouse  1099 --------------------------------------------------------------LDS 1101

  Fly  1596 QTLVIYKSH---TGRSAQNGKLEQTSSIQFNCLNLAICVERWYTIFDFFGLVSVDNVNEKYP-EE 1656
            ..:.|||..   ||:.                            :|. |.::|..:....|. .:
Mouse  1102 DKMAIYKKALYITGKE----------------------------VFS-FKMISYMDATAGYAYTD 1137

  Fly  1657 MKLVEKHIDKVCSKLKVSIRSFNFTLIRNESLLSRVNVSNAVFMILQDPYSKIVEGCLGSVSVND 1721
            |.:|:..:                                           .:..||:..|.:.
Mouse  1138 MSVVDIRV-------------------------------------------HLTVGCIEVVFIT- 1158

  Fly  1722 LTKYGNIYKQKFLTSGTEALNFVYKKKLVDLEALNTLDTDSTLRINMSAVHYIHTKRFSTELHVF 1786
                      |||.|   .|.|:                     .|..|
Mouse  1159 ----------KFLYS---ILAFI---------------------DNFQA---------------- 1173

  Fly  1787 VKDLLQLQTPVIRKLKKHG-SEQNMRPSKMKLVIQADSPVIVLPSSYNRNEVIIAYLGQFSLKNS 1850
            |||.|...|....::...| .|...:.|:..|.:...:||:::|.|.....|.:|..|..::||.
Mouse  1174 VKDALAEATVQAAEMAADGVKELARKSSRFALDVNIKAPVVLIPQSPVSQNVFVADFGLITMKNI 1238

  Fly  1851 FHFASDNNIISKMSATPSKDEI---LDVMRIDLVNINLFSGERSSMKAKADQEKDRIIIADMNFL 1912
            |           ::.|.::..|   :|::.|.|..:.|:   ||..:....||     :.|: .|
Mouse  1239 F-----------VTVTETQSNIPPVIDLITIKLSKMRLY---RSQFRNDTYQE-----VLDL-LL 1283

  Fly  1913 RLGQPFFNESCFLHLQLERNLSADAHRVCPDISVQGTFSKLSGIINIQQYKLIRSFLNNNIGEQT 1977
            .|.         |.:.:|||||.:.::..|..:::.....:..|::.:....:...|:.||....
Mouse  1284 PLN---------LEVIVERNLSWEWYKEVPCFNIKAQLKPMEFILSQEDLTTVFQTLHGNIWYGQ 1339

  Fly  1978 DDIYMNYHNNSCTSIERLSTINLMPKNEVSKIVSILISIRILLEDVSLLLALNTS------QSAA 2036
            |             :...|:.|..|:...|.:.|        ..|.|....:..:      |::.
Mouse  1340 D-------------LSAPSSANKDPETMTSGVTS--------PPDHSPATVVTAAVVEVHPQASQ 1383

  Fly  2037 IEPLACIHFLKSTLEIDLFSDGSQDI------------------DLISS---------------- 2067
            ...:..:.|....|.:.|:|.|..:.                  ::|||
Mouse  1384 AHTMLNVSFQTDYLTMALYSPGPDEASFTDVRDPSLELAEFKLENIISSLKIYTDDSTVFSFSVK 1448

  Fly  2068 NILIVDERNESDKSNENVFKNILEPSKKEVRIENSVQVEVHCRKKATFSKYTIMLNNMRVFALLS 2132
            |.::.|:|:...|:...:....:...||::       |::..||..||.....::..|.|.|.:.
Mouse  1449 NCILDDKRSHVMKATPRMIGLTVGFDKKDM-------VDIKYRKIKTFVVTDAVVQEMYVCASVE 1506

  Fly  2133 FLDQLKSYLQEDSPAPVVNNAANQIAQKPQIDTSIST--------------EYVVNITDSEIIFA 2183
            ||            ..|.:...:.......::||:.|              |..:.|.:.||:|.
Mouse  1507 FL------------MTVAHIFFDAYMTSTALETSVQTRTTREAPAQELGKWEMNILIKNPEIVFV 1559

  Fly  2184 EECSRLDSNAIILKSTTVICYK--PNSNIVPLSLDINHLEIFSCT-LDAEEESAL-SIIDPFTLI 2244
            .:.:|.|:.|:::.:...||.|  |.||.|..:  |..|::.:|. |..:.:..: :::.|..|.
Mouse  1560 ADMTRNDAPALVITTQCEICCKGEPTSNTVTAA--IKDLQVRACPFLPVKRKGKVTTVLQPCDLF 1622

  Fly  2245 IELRS-----NCLNILIQKHLNIRLSYVDVK-LFSRMARLLPTQTSRPKNVISKADSDLEKAAPL 2303
            .:...     ..::|.: |.|.:::|.|.:. :.:..:.|..|:.:.|:...|.
Mouse  1623 YQATQLGRDPQMIDISV-KSLTLKVSPVIINTIITITSALYTTKETVPEENTSN----------- 1675

  Fly  2304 VAMGFEISDCLYAMQINNWRINDAAIWLSQQKQNTYRNPALEMKTA--VVDASLISVFIIDDCMD 2366
            :|..::..|   ...:..|       :|.:..::....|..|:...  .::..:.|:||:   ::
Mouse  1676 IAHLWDKKD---TKNLKMW-------FLEESNESEKVVPTNEVMPGGETLNLRIDSIFIV---LE 1727

  Fly  2367 A-----DVPLLEVSLSKFLLNFTFQTQDPNPKETNIRHYSLGNI--DTEVSVNYYNRRLSGWEPV 2424
            |     .||:|       |....|..:..|       ..||.|:  ..|:.|:|||.....|||:
Mouse  1728 AGIGHRTVPML-------LAKACFSGESKN-------WLSLINLHCHLELEVHYYNEMFGVWEPL 1778

  Fly  2425 AETWES---------NLNWKYTK----------GHLDNKK--RFEIGIS--SKQMLKLNVTSTFI 2466
            .|..|.         ||..|..|          ...:|.|  .::..||  |:..|.:.::...:
Mouse  1779 LEPLEIDQTDDFRPWNLGIKMKKKAKEAIVESDSEAENYKVPEYKTAISFYSRDQLNITLSKCGL 1843

  Fly  2467 ELFHMVLKNWTNDFNDNGAKNFRQRSPFIPFALQNLSGTPLLFKPIYAPLGDLTRSD---LQQVE 2528
            .:.:.:::.:|.....:.:...|..:||:.|   |..|..:...|          ||   :..|.
Mouse  1844 VMLNNLVEAFTEAATGSSSVFLRDLAPFMIF---NSLGLTVSVSP----------SDSFSVLNVP 1895

  Fly  2529 LIKNWYSVQPNETKTFDFSQKSKLRHVHSHQLNLHQIFVQIHGWTLIGP--------ISVDKVGM 2585
            |.|: |.::.:|:.:.|:.:.....|.::......::|     :.|:.|        |.:.|||.
Mouse  1896 LAKS-YELKNDESLSMDYVRTKDNDHFNAMTSLSSKLF-----FILLTPANHSVADKIPLTKVGR 1954

  Fly  2586 FFRTTKLDSQFLTKSRIVFDISLIGSAQKLIKVKSSLGVIN--KLDRNVFLKMTLKGTHSDGLSS 2648
            ...|.:.....:.:| |:..|..:..::| :.::|.:.:.|  .:..:||          :|.:.
Mouse  1955 RLYTVRHRESGVERS-IICQIDTVEGSKK-VTIRSPVQIKNHFSIPISVF----------EGDTL 2007

  Fly  2649 ISVIKPNDELSVPLKFIDASLYVAHNTSESDAYEDTGFS-----NEEILWKACGKDDTRQLLAGY 2708
            :.:..|.:|.::||....:||.:.....:....|...|.     :.::|.|.|           .
Mouse  2008 LGIASPENEFNIPLASYRSSLSLVPEDQDYQLCEGIDFEEIIKYDGQLLKKKC-----------R 2061

  Fly  2709 DTNKSILYTFVNI--------SREIYHCKEQNLPGHKITLLPPLKINNMLCCDLMFKIH--EHAT 2763
            .||.|.....:||        |..:|.....:|| :.:.|.||:.|.|:|...:.:.|.  |:..
Mouse  2062 STNPSKKSFVINIVPEKDNLASLSVYSEDGWDLP-YVLHLWPPILIRNLLPYKVAYYIEGIENTV 2125

  Fly  2764 GRINSSESVNIYNVNICQ-PLNLSITLD--NFQLSGQLKIPVSHRGVIEPKLK-LIDIQKRELHV 2824
            ..::...|..||||.:.| .|:|.: ||  |.....:..|..|.:.:...... |.:::|.:|.:
Mouse  2126 VTLSEGHSSQIYNVEMDQAKLHLKL-LDYLNHDWKSEFYIRSSQQDINFINFTCLTEMEKSDLDI 2189

  Fly  2825 RVSIQSVPGKGMELYISAPVWIINKTGLPLIYKQEGTSHTAAGQFEEHETARQVAPLMFSFSDQE 2889
            .:.:....|:.:..:.| |.|::|||...|.||.:|        ...........|::|||...
Mouse  2190 AIHMTYNTGQTVVAFHS-PYWMVNKTNRMLQYKADG--------IHRKHPPNYTKPVLFSFQPN- 2244

  Fly  2890 GSPALVLRLGKAYGSNNMWCKSFSTHKDLADR----------DLRAENTKGSYAIGISVRRGRGL 2944
                        :..||...:...|..:|:|:          .:|.:..|..|.:|:::....
Mouse  2245 ------------HFFNNNKVQLMVTDSELSDQFSIDTVGSHGAIRCKGLKMEYQVGVTINLSS-- 2295

  Fly  2945 YACTTFVTLSPRFHLHNRSGYKLEFMQLCDIVNYDRPDPRKIISAPVDCNFAFHWPNWDQEQIIC 3009
            :..|..||..|.:.:.|:|.|.:.       |..:..|               .|.:.|.||
Mouse  2296 FNITRIVTFIPFYMIKNKSKYHIS-------VAEEGSD---------------KWLSLDLEQ--- 2335

  Fly  3010 VRIPEIECCCWSKGIPIKDVQSLYINVRNEWGEMFFLRLEIISKDATFILLFTDARTLPPPIRI- 3073
                         .||.             |.|           :|:.|||....|:..||.||
Mouse  2336 -------------SIPF-------------WPE-----------NASNILLIQVERSEDPPKRIY 2363

  Fly  3074 ----DNC-------------SEV-------VINFS-------------QLRSKPVWITPVRPQSS 3101
                |||             :||       ||.||             ..:|.||...    |||
Mouse  2364 FNKQDNCILLRLNNELGGIIAEVNLAEHSTVITFSDYHDGAATFLLINHTKSDPVQYN----QSS 2424

  Fly  3102 LSYVMD-------------DPLGQQILLMEAPGGNMIEFPINNKNNI-------KKTLTYTNFIY 3146
            |..:.|             ||:|.:.|.... |.:..|  :.:|:::       |||:...:|
Mouse  2425 LGEIEDSLPPGKAVYYTWADPVGSRKLKWSC-GQSYGE--VTHKDDMMTPISVGKKTIYLVSF-- 2484

  Fly  3147 IAFQGTFERSNEEENTHRQLVLGVRGKKVVIVEKNSGDRSQLWLMNSNGQLEHEGSTPPIQTNDA 3211
              |:|.           ::::|.....:|..|...| ::::|      .:||
Mouse  2485 --FEGL-----------QRIILFTEDPRVFKVTYES-EKAEL------AELE------------- 2516

  Fly  3212 NAVRLVLDLEKAPNPMEFTNLVVRTPNKQRVTTQTWRFENGRLMCHANMCVQSRFGESGLKPNYE 3276
                :||.|:      :....:|....||.|
Mouse  2517 ----VVLALQ------DVGISLVNNYTKQEV---------------------------------- 2537

  Fly  3277 AVVGRTEN----RASSSKQI---PIG-QHIVAQKLRPGSGQLELSTKMDGPISTIEICDIKIKQN 3333
            |.:|.|.:    .|...|:.   |:. :|  .:||.....:...::.::..:  :|:.:|.::
Mouse  2538 AYIGITSSDVVWEAKPKKKARWKPMSVKH--TEKLEKEFREYTEASPLEDKV--VELDNIPVR-- 2596

  Fly  3334 SVFLTPDLLWMHASLNNRQITDKGKVSFVHEYLINVELVKGIGISIIARKPCEEIMFISLDHINC 3398
               |||       |.|:.:|.....:.....||                 |..::.:.:
Mouse  2597 ---LTP-------SGNDMKILQPHVIPVRRNYL-----------------PALKVEYNT------ 2628

  Fly  3399 DIVQSALENSLDLNIAYIQIDNQLLDAVSPIALH--------TQTSNDLEETQNAVVLKLKMLPS 3455
                ||.::|..:.|..|||.||:..|:.|...:        |..|.....|..::|::     |
Mouse  2629 ----SAHQSSFRIQIYRIQIQNQIHGAIFPFVFYPIKPPRSVTMDSAPKPFTDVSIVMR-----S 2684

  Fly  3456 PNKNAII-FKYLTLDLKPSTASLEEKLILKVASFLGYGKINRQNLSVQYQFENTDDKPFLQDMKR 3519
            ...:.|. .||..:.::....||:...:..:|..:...::.          |.|:.:.|.:|::.
Mouse  2685 AGHSQISRIKYFKVLIQEMDLSLDLGFVYALADLVTKAEVT----------EKTEVEHFHKDVEA 2739

  Fly  3520 Y----------------YFENLSIGATQVRLSAFTSS-------------KLPV-ELHETKKALG 3554
            :                .||...|...::.||...||             .:|| .|:...|::|
Mouse  2740 FEQEYEVVSSVDQSQVNLFEYFHISPIKLHLSVSLSSGRDEAKDSEQHGGLIPVHSLNLLLKSIG 2804

  Fly  3555 LTLIKFEDALIELDRYSDKLHFETMDVYRKELKKHYINQ-VKWHAAAILGSVDFLGNPLGFANDL 3618
            .||...:|.:.:|..:.....|.|....:.|:.:||..| :|.....||| :|.||||.|...:.
Mouse  2805 ATLTDVQDVVFKLAFFELNYQFHTTSELQSEVIRHYSKQAIKQMYVLILG-LDVLGNPFGLIREF 2868

  Fly  3619 SEGVSGLIFE---GSV--------------KSLVKNVTHGISNSTAKLTETLSDSLGKVVLDDHD 3666
            ||||....:|   |::              |:||.....|::.:.:|:|..::..:..:.:|:..
Mouse  2869 SEGVEAFFYEPYQGAIQGPEEFVEGMALGLKALVGGAVGGLAGAASKITSAMAKGVAAMTMDEDY 2933

  Fly  3667 NETRQRILELQSNTSGGHLAAGLKGLGFGLLGGVTSIVRHTYDGATSDGVPGFLSGLGKGLVGTV 3731
            .:.|:..:..|.......:..|.|||..|.:.|:|.||.....||..:|..||..|:||||||.|
Mouse  2934 QQKRREAMNKQPAGLREGITRGGKGLVSGFVSGITGIVTKPIKGAQKEGAAGFFKGVGKGLVGAV 2998

  Fly  3732 TKPIIGVLDLASETASAVRETSRDSHRNAPERKRLPRCVTGAPGGLLPLYSNRQSKGQQYLYLIN 3796
            |:|..|::|:||.|...::..:..|.   .|..|.||...  ..|::..|..|...|.|.|.::.
Mouse  2999 TRPTGGIIDMASSTFQGIKRATETSE---VESLRPPRFFN--EDGVIRPYRLRDGSGNQMLQVME 3058

  Fly  3797 QKNFSE 3802
            ...|::
Mouse  3059 NGRFAK 3064

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vps13D	NP_729825.2	Chorein_N	4..112	CDD:315323	38/107 (36%)
		VPS13	147..368	CDD:318996	54/255 (21%)
		VPS13_mid_rpt	<656..837	CDD:318998	40/183 (22%)
		VPS13	<2039..>2694	CDD:330393	140/762 (18%)
		SHR-BD	2836..3113	CDD:310922	69/337 (20%)
		VPS13	<3346..3802	CDD:330393	120/512 (23%)
Vps13a	NP_766616.2	MRS6	4..>2005	CDD:227376	485/2854 (17%)
		Chorein_N	4..113	CDD:289396	38/108 (35%)
		VPS13	142..371	CDD:293513	54/256 (21%)
		TPR 1. /evidence=ECO:0000255	212..245		6/32 (19%)
		TPR 2. /evidence=ECO:0000255	373..406		6/36 (17%)
		VPS13_mid_rpt	568..791	CDD:293515	57/343 (17%)
		FFAT. /evidence=ECO:0000250|UniProtKB:Q96RL7	838..844		3/5 (60%)
		VPS13_mid_rpt	1141..>1236	CDD:293515	28/188 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1343..1365		6/29 (21%)
		TPR 3. /evidence=ECO:0000255	1806..1840		6/33 (18%)
		TPR 4. /evidence=ECO:0000255	1999..2034		9/44 (20%)
		SHR-BD	2202..2445	CDD:284143	66/332 (20%)
		Required for mitochondrial localization. /evidence=ECO:0000250|UniProtKB:Q96RL7	2607..3166		117/506 (23%)
		VPS13_C	2758..2935	CDD:293514	45/177 (25%)
		ATG_C	2938..3017	CDD:286423	30/78 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D4159at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1642
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.950