Protein Alignment Vps13D and vps13a

DIOPT Version :9

• Sequence 1: NP_729825.2
• Gene: Vps13D / 39448
• FlyBaseID: FBgn0052113
• Length: 3919
• Species: Drosophila melanogaster
• Sequence 2: NP_001342827.1
• Gene: vps13a / 2540516
• PomBaseID: SPBC21C3.01c
• Length: 3071
• Species: Schizosaccharomyces pombe
• Alignment Length: 4159
• Identity: 789/4159 - (18%)
• Similarity: 1395/4159 - (33%)
• Gaps: 1455/4159 - (34%)

  Fly     1 MLRDLITWVLNTYLGKYLENLNSAQLSVALLSGEVELENIPIRKDALRSFNLPVEVTAGSIRKIK 65
            ||..|:..:||..||.|::||::.||::.:..|.|.|.|:.|:.:||....:|:|:|:|.|....
pombe     1 MLEGLVAGLLNKILGSYVDNLDTKQLNIGVWGGHVSLHNLRIKPEALDKLGIPIEITSGLIGTFT 65

  Fly    66 LQIPVRQFRTSPWCISIEGLFCIICP--KNLDNWDYEKEKLQDLEYKLAVLDTAE---AGWRSEK 125
            |:||....|.....|:||.::..|.|  ||....|..::..|.|  |...||:.|   ..:|...
pombe    66 LEIPWSNLRNKSLTINIEDIYLSIHPQAKNSLTRDELEQSQQAL--KQEQLDSFEILRKNFRETL 128

  Fly   126 GKQMESYYFSSYNNWLKYGTNMATNIIDNIELKISDVHFRFEDIVDTGKSKICTGIKIGSLTAQS 190
            .:...:...|...::::|   :...:.|||::.|..:|.||||.:...:.....|:.:.||...|
pombe   129 EESSSNPNISRKQSFIEY---LIAKLTDNIQIYIERIHLRFEDNLSDLEKPYSLGLTLYSLRVTS 190

  Fly   191 CDCDWTNGSYKMNNNEMN----YKLVELKELSVYWDLLHEDIKCQSYSNQEI---LEKMHSTCEL 248
            .|..:|  .|.::.:.:.    :|::.:...|:||....|..||.  :.::|   |:.:..:.|.
pombe   191 TDASFT--EYLLSTDPIPSSCIHKIITVDYFSIYWISKCEISKCT--TTEDIFSYLKNLIPSAEK 251

  Fly   249 R-SHNFIIKPICATAR--WKRDKCQQVIRTKDKPRVSCELLVPEVVIDISKVQRLQMLDKLSEIR 310
            . ::|:|:||:.|||.  ..|....|:::.:.|      |.|.|:.|.:|......:|..:...|
pombe   252 SPAYNYILKPLRATAHVVLFRHPTDQIMQLRGK------LSVEEISITLSDHMYYSLLGVIDYFR 310

  Fly   311 QVKEVRQYRLKRPTCTVESNPIAWWKYATICHGFDFKKNEEKWL------MLKENLRYMLLYKSI 369
            .|.:.:.|...||..|.:..|:.|:|||.:.......::...|.      ...:.:.||.:.:..
pombe   311 VVMKQQYYLQYRPKSTPKEKPLEWFKYAILVVKDSVHESRYHWTWKYFKRRRDDRIAYMHIIRKR 375

  Fly   370 ILNPNENLSAADKEFKAYIESDRKISDLTIMRRICFEKVFTKGFAFESQNE---QGKNMLFHWFP 431
            .|  ||.:|..:.:.:..||......||...|    .:|.|.  ..|.:|.   :.|....|...
pombe   376 YL--NEQISKEEIDLQKKIEKRNSTYDLIKYR----SRVHTS--LIEERNSIYLKPKTSAAHGLY 432

  Fly   432 NWMGWYANSPSTPNNE----QDESLKHLED----DILVALENSLQ---NSSDLKSDAVFGHFSIK 485
            :|...|...|.:.:.:    .|::...|.|    :...|:|.|.|   ::.:|..|....:..:.
pombe   433 DWFSGYIRKPQSQDEDTLASTDKTAADLTDQEQKEFFSAIEWSGQLYPDTVNLDPDMCMANVEVS 497

  Fly   486 LLKGLVILQTEDKLNDGRNKSMEMQFNNFSAYLQLSPQLTSYTVGISLQEVYLIDKTSSDTMHNY 550
            :.||..::|:.  :|......::.:|.:|:....:.||  |..:.:||:::.:.|..::..:.
pombe   498 IAKGSFVIQSH--INGRVIPLIKQRFESFATECFIRPQ--SLKLKVSLKDLDMFDGITNPELE-- 556

  Fly   551 LIKPQTGNTATPNQLV--KNAALQEDILFQLQYENCNHLRF-------------QLNIKSKGLDL 600
                       |.:::  |.:..:.:.|.::......||.|             .|.:..:.|.:
pombe   557 -----------PARVIFAKPSVEESESLQKIPEAYRTHLFFLLLDTKPVYKASSTLIVHLRTLVI 610

  Fly   601 IYNEDAIQWLLDFLADSNSFKYSPRNRVAKKTDFMKNWNEMFSGNEVNRKIWMFEIEIFAPRIIF 665
            |||...|:.||.|..       .||.::    :.:..|
pombe   611 IYNRVCIESLLAFFV-------PPRTKI----EHVSEW--------------------------- 637

  Fly   666 LENYKVSNSLMVL-------LDFGKLEMRK---MEVKRVIPVIESAVTENTSDDDETYLTPCSTP 720
              .|..:..:|.|       ||:. |||.|   |.:....|:|  .|.|..:|
pombe   638 --GYSAAAKVMTLARQTRASLDYA-LEMHKTSDMTIDLQAPLI--VVREECTD------------ 685

  Fly   721 PASEKSGSESPTLL-------------------ENPKTESFLNKNVQLEYVLHNKIYDKYLINFT 766
                   .:||||.                   :..|.:|....|.||:. |.|.:|||:.|:..
pombe   686 -------LKSPTLFLDVGRALVHTQLVDDAIIDKFRKLQSKKINNEQLKQ-LENLMYDKFTISLF 742

  Fly   767 NLQVLV-CKYEERWQACLKTSSNFHLIDKFNINLTLEQRNIFTVDPEYPSFMLFGTCPTILIHGN 830
            |::.|: ..||..|: ||....::|::.:.::::..|
pombe   743 NVRCLIGPDYETGWR-CLPKGCDYHILKECSLDINFE---------------------------- 778

  Fly   831 EELINNCCNIMKPIIKASKEMENIYRGGNTIYASERIKNLAEDDRSRVVIEFVMDQLVIEMQST- 894
            ..::....|:.|  .|.|..|::                      :.::...|..::.|.|.|.
pombe   779 ISILQKATNLTK--FKVSSHMKH----------------------AEIMFSDVQYKVFINMMSNI 819

  Fly   895 --ERSIAELQIIGARAGLTKEPHETNISMSVHGLLLVDAIQSFGPDFELLVASHRHVGMDSLSGS 957
              ...:||:..                           ..|.|               :|:
pombe   820 LPTLPVAEIPF---------------------------TYQQF---------------LDA---- 838

  Fly   958 LKHSAIVSPTSPGSPNFFDRATSPHMITKAVQNIKMGDRSTEFCDDEDSTALISVDIKIVPPNES 1022
                  |.|     |.|||                                        .|.|
pombe   839 ------VKP-----PPFFD----------------------------------------APDN-- 850

  Fly  1023 NSMQLHTTSITFNSLDIIANQDTIIEILNFAKRTLLAQNIFPSESPESPKEATEAPVD-VVDQVD 1086
                   ..||..||...||::|..:        .:||.||          |....|| .:..:.
pombe   851 -------FQITHTSLGSHANENTAAQ--------FMAQQIF----------AFYFKVDYAICSLY 890

  Fly  1087 HKSHNEIF-----FDFFRLNILLLYTIKRDKFNVGRKVGTVTLTEAKINASFQSDLSIIGSLGGI 1146
            .:|.|.:.     |..|.:::::      .||:.        |..:|:|
pombe   891 RRSENYLIPVVRAFTEFYIDLVV------RKFDY--------LVTSKLN---------------- 925

  Fly  1147 QVIDITSEAFCHPRILSVGRDQIL-RASDTNKQTVLSQLSNEIYSNNYNEETKSDESDAISFQS- 1209
               |:..:.|.:|..|.   |.:| |:|.:.|             ||:      |::..||:.|
pombe   926 ---DLVIKEFTYPSSLC---DNVLVRSSPSPK-------------NNF------DDTVFISYTSI 965

  Fly  1210 -HWSDKTTCTFQMRMASASYTHCPRFLRDVNACITYFKRSLREFATSIGNKATDMAKEFVQQVRA 1273
             :.|.:....::....:.:.......|.......::....:|...||:.::.  |..|..:..|.
pombe   966 DYDSPELDSVYEGVRTTIAVVLSDLILNVEPTGFSFVYDFIRATFTSLNDEY--MIGEDPELTRK 1028

  Fly  1274 VEQIGPVYPQ--RNRQDNWLDIIISSPIIILPISNTSTNVLIANLGKISCSNAVKCDSD------ 1330
            :..:..:.|:  ..|.|| :||.:                             ..||..
pombe  1029 ISPVEGIIPEDANVRFDN-VDIFL-----------------------------YDCDQHFSTVCL 1063

  Fly  1331 -------EFNESYTIEIKNTYVYSLNIDEGEYSFNVHPAKNKDAIPILHDTAITLQLYAGYSDDN 1388
                   ||.|.:.::.:   .|.|.:.....|.|  |.|   .|..:.|..:.:..|..|
pombe  1064 YSANMHMEFREKFFLQAR---FYDLEVKNHMKSNN--PPK---TIVKIDDNDLFIFKYESY---- 1116

  Fly  1389 DEDKQLNR------FSIK-GSMVEALKVS---------LNRKQYELLLESIRYATNFSNEVLNES 1437
            |..|.:::      :.|. ||:....:.|         |..|:::.|..|||||..:
pombe  1117 DIPKDISKPTCDCVYDISFGSLTFYFQKSYFNAIYDFLLKLKRFQELFSSIRYAIYY-------- 1173

  Fly  1438 DELDQNGDIEPTANIDAESIISTTIQFSVPVFQINLQNEYHNDLINLTFKNF--NVKHISKGFDK 1500
                                                  :.:.:.::||:..|  .:||....||
pombe  1174 --------------------------------------KLYGNKVSLTYPKFELRIKHPKVYFD- 1199

  Fly  1501 DVEVVLKSVLMEDLKSDLTSPFRNMVTSVDLEQKIKKNEMTS-SSCPDLPSYCNSLKNRSSSVPS 1564
                   .||.|:         ||    ..::..:|.....: |.||.:.      ||...|:.|
pombe  1200 -------DVLDEE---------RN----CRMQLIVKPQSFYAFSKCPIVE------KNSKKSIFS 1238

  Fly  1565 CFYNHMQVKVFGGDQKYTSSNKNELGKKKESQTLVIYKSHTGRSAQNGKLEQTSSIQFNCLNLAI 1629
            |                      |: .|.|..|.|...||     .:..:|:      |.::|.:
pombe  1239 C----------------------EI-TKVEFHTAVPSSSH-----HDVLMEE------NNVHLDL 1269

  Fly  1630 CVERWYTIFDFFGLVSVDNVNEKYPEEMKLVEKH-------IDKVCSKLKVSIRSFNFTLIRNES 1687
            ..:..||.    |........:..|..:.:.:.|       ||...:..:|....:....:|.|
pombe  1270 TYDANYTT----GAYVFKATGDLDPVILNMCQSHHVIFWDLIDVATTFARVDSSFYTSENLRRE- 1329

  Fly  1688 LLSRVNVSNAVFMILQDPYSKIVEGCLGSVSVNDLTKYGNIYKQKFLTSGTEALNFVYKKKLVDL 1752
                                                     ..:.|..||| |....:.||.| :
pombe  1330 -----------------------------------------LDKAFDRSGT-AAKLKHPKKTV-V 1351

  Fly  1753 EALNTLDTDSTLRINMSAVHYIHTKRFSTELHVFVKDLLQLQTPVIRKLKKHGSEQNMRPSKMKL 1817
            |.|:.|.|.:...|.::    :||..|    .:...||.||.:
pombe  1352 ETLDILTTFNLPEIRLN----VHTDDF----WIHGGDLTQLHS---------------------- 1386

  Fly  1818 VIQADSPVIVLPSSYNRNEVIIAYLGQFSLKNSFH--------FASDNNIISKMSATPSKDEI-L 1873
                                |:::.| |||..:|:        |:.|:  |......|..:.: |
pombe  1387 --------------------ILSFFG-FSLDYNFYSSGRCYAEFSIDS--IQLKDCNPQDNVVFL 1428

  Fly  1874 DVMRIDLVNINLFSG--------ERSSMKAKADQEKDRIIIADMNFLRLGQPFFNESCFLHLQLE 1930
            ||:.....:..|.:|        .|.::....|..|   |..::|:|     :...|.|:|.
pombe  1429 DVLEYSENHNRLVNGCLEYDSQNPRYNLVLDIDSPK---IFVNLNYL-----YSIWSIFVHW--- 1482

  Fly  1931 RNLSADAHRVCPDISVQGTFSKLSGIINIQQYKLIRSFLNNNIGEQTDDIYMNYHNNSCTSIERL 1995
                   ||        ..:|.|..:..: :|.::.:...|..||::   |..|
pombe  1483 -------HR--------AYYSHLDYLTEV-EYFIMGNPNQNACGEES---YWYY----------- 1517

  Fly  1996 STINLMPKNEVSKIVSILISIRILLEDVSLLLALNTSQSAAIEPLACIHFLKSTLEIDLFSDGSQ 2060
                                 ||...|::||                  |.::..:.:|:|
pombe  1518 ---------------------RITFVDMTLL------------------FFRNVSDANLYS---- 1539

  Fly  2061 DIDLISSNILIVDERNESDKSNENVFKNILEPSKKEVRIENSVQVEVHCRKKATFSKYTIMLNNM 2125
             :.:....:||..:                                         |.:.:..|||
pombe  1540 -LPMFFGELLITQQ-----------------------------------------SIFAVTANNM 1562

  Fly  2126 RVFALLSFLDQLKSYLQEDSPAPVVNNAANQIA--------------QKPQIDTSISTEYVVNIT 2176
            ::.|               .|.....|.:||:|              .|.||        :.|||
pombe  1563 KINA---------------CPLSETANISNQLADPFGFRYTYSQHTVNKIQI--------ITNIT 1604

  Fly  2177 DSEIIFAEECSRLDSNAIILKSTTVICYKPNSNIVPLSLDINHLEIFSCTLDAEEESALSIIDPF 2241
                        ||.::.:|::|                                      ::.|
pombe  1605 ------------LDFDSFVLRTT--------------------------------------VNDF 1619

  Fly  2242 TLIIELRSNCLNILIQKHLNIRLSYVDVKLFSRMARLLPT------QTSRPKNVISKAD---SDL 2297
            ..        |..:::|..|...:..||          ||      :.::...:.:..|   ..:
pombe  1620 LF--------LQTILRKIYNFYYALYDV----------PTTDVELLKRTKDDQLATNPDFLQLSV 1666

  Fly  2298 EKAAPLVAMGFEISDCLYAMQINNWRINDAAIWLSQQKQNTYRNPALEMKTAVVDASLISVFIID 2362
            :...|....|..|....:.:.::..|:    :.:||..
pombe  1667 DTGQPSSVFGIRICKEEFLLTVDGIRL----LVISQLH--------------------------- 1700

  Fly  2363 DCMDADVPLLEVSLSKFLLNFTFQTQDPNPKETNIRHYSLGNIDTEVSVNYYNRRLSGWEPVAET 2427
                 |:|||.:::..|.::....:.:.|           .|...|:.:|:||...|.|||..|.
pombe  1701 -----DLPLLNINIKPFQVDLNDWSSELN-----------SNAHLELFMNFYNFSNSHWEPFLEP 1749

  Fly  2428 WESNLNWKYTKGHLD---NKKRFEIGISSKQMLKLNVTSTFIELFHMVLKNWTNDFNDNGAKNFR 2489
            |:..:       |:.   |..:..:.:.|::.|.|.:|...||..|.   .:|...:
pombe  1750 WKVGV-------HISRNPNTSKTAVHVFSREKLDLVITPQLIETLHF---GFTKVIS-------- 1796

  Fly  2490 QRSPF-------IPFALQNLSGTPLLFKPIYAPLGDLTRSDLQQVELIKNWYSVQPNETKTFDFS 2547
              :||       .|:.:.|.:|..:   .::|...:...|.::.:|         .||...:.|.
pombe  1797 --TPFPIEFKCDAPYRIHNYTGHAV---SVWADFENAADSCVRHLE---------NNEETDWKFE 1847

  Fly  2548 QKSKLRHVHSHQLNLHQIFVQIH----GWTLIGPISVDKVGMFFRTTKLDSQFLTKSRIVFDISL 2608
            :..:::.|.....:  :.::..|    .|..:..:.|::||..........|...|..:|.|::|
pombe  1848 EWRQMQDVVKQDQD--RSYIGFHFENSKWESLRHVRVNRVGEHIYPLISYDQDELKHYMVVDVNL 1910

  Fly  2609 IGSAQKLIKVKSSLGVINKLDRNVFLKMTLKGTHSDGL--SSISVIKPNDELSVPLKFIDASLYV 2671
            .....|.|.::|.|.:||:..    :::.:....|||:  |.|..:.|.:..|:|::  .|..|.
pombe  1911 GEDYIKHITLRSPLLLINETQ----MEIDVVFCDSDGIQRSQIYHMSPEESCSLPIE--TAYYYS 1969

  Fly  2672 AHNTSESDAYEDTGFSNEEILWKACGKD--DTRQLLAGYDTNKSILYTFVNISREIYHCKEQNLP 2734
            .|....|:.  ...:::|.|.|    ||  |.:|.|.....:.:...|...........|.|.:.
pombe  1970 IHIRPVSEF--KFNWTSEAISW----KDLVDNKQSLVTCQHSDNTFSTPACRFAANAELKSQTIS 2028

  Fly  2735 GH----KITLLPPLKINNMLCCDLMFKIHEHATGRINSSESVNIYNVNI--C---QPLNLS-ITL 2789
            .|    .||:...|::.|:|..||..:|.:      ...|.|.:.||.|  |   ..:|:| :.|
pombe  2029 NHYPFMHITISALLEVKNLLPIDLNIRIID------KDQEGVWMSNVGIGECAYVHSINISHVLL 2087

  Fly  2790 DNFQLSGQLKIPVSHRGVIEPKLKLIDIQKRELHVRVSIQSVPGKGMELYIS------------- 2841
            ...:.|....:|.|...:|...    ..|:|:.::.:::|.  |:...|.:|
pombe  2088 LQAESSESHYLPSSLATIITND----SAQERDEYMTITLQG--GRKTRLGLSYTEKYPGIYHIEI 2146

  Fly  2842 -APVWIINKTGLPLI------YKQEGTSHTAAGQFEEHETARQVAPLMFSFSDQEGSPALVLRLG 2899
             :|..||||:|..|.      |.:...|..:....|:    .:|.|.|||:|...||....||
pombe  2147 FSPYIIINKSGSFLFVGPKNDYNRISFSSASLSSGED----GKVVPCMFSYSHNYGSRRCRLR-- 2205

  Fly  2900 KAYGSNNMWCK--SFSTHKDLADRDLRA-ENTKGSYAIGISVRRGRGLYACTTFVTLSPRFHLHN 2961
               ..|:.|.:  ||.....:.:.:|.: |:....|.:||.|..|...|:.|..||::.||.:.|
pombe  2206 ---ADNSNWSEPVSFDAIGSVFEVELPSKEDHNKVYRLGIFVETGPDGYSKTNIVTITSRFIVRN 2267

  Fly  2962 RSGYKLEFMQLCDIVNYDRPDPRKIISAPVDCNFAFHWPNWDQEQII---------CVRIPEIEC 3017
            ::.:.|                  :|:.|.:...|...|  :.|:.:         .:::...:|
pombe  2268 KTRWSL------------------VIAEPYNDFIAEIAP--EGEEFLTYLRKHSHPMLKLSSSDC 2312

  Fly  3018 CCWSKGIPIKDVQSLYINVRNEWGEMFFLRLEIISKDAT-FILLFTDARTLPPPIRIDNCSEVVI 3081
            ..||....|:::.|.::.:....||. .|||||:.|:|| ||.:|.:  |...|..|.|.|.|::
pombe  2313 YLWSSSFYIEEIGSTHVRLMTSEGEK-LLRLEIVIKNATIFISIFEE--TGDWPYYIKNESGVLL 2374

  Fly  3082 NFSQLRSKPVWIT------------PVRPQSSLSYVMDDPL-----------GQQILLMEAPGGN 3123
            .|.|:  .|:..:            .:.|.|.:.|..|.|.           .|:.|...|..|.
pombe  2375 KFWQV--NPIDASEGKNNTALLKYHDIPPHSEVKYSWDYPCCANKEIALCYGDQKCLTTLAEIGP 2437

  Fly  3124 MIEFPINNKNNIKKTLTYTNFIYIAFQGTFERSNEEENTHRQLVLGVRGKKVVIVEKNSGDRSQL 3188
            :..|...:.:|      .|.||                 .|.:|  ..|...:::.|:
pombe  2438 LSPFKFTDASN------NTKFI-----------------SRDIV--ANGLSKILILKD------- 2470

  Fly  3189 WLMNSNGQLEHEGSTPPIQTNDANAVRLVLDLEKAPNPMEFTNLVVRTPNKQRVTTQTWRFENGR 3253
                               .:.:.|||
pombe  2471 -------------------YDPSKAVR-------------------------------------- 2478

  Fly  3254 LMCHANMCVQSRFGESGLKPNYEAVVGRTENRASSSKQIPIGQHIVAQKLRPGSGQLELSTKMDG 3318
                              ||...:.|. ||.|..:.:|...|              ::||.|.
pombe  2479 ------------------KPKIYSKVS-TEERDFNLEQFDSG--------------IDLSVKF-- 2508

  Fly  3319 PISTIEICDIKIKQNSVFLTPDLLWMHASLNNRQITDKGKVSFVHEYLINVELVKGIGISIIARK 3383
                                                                |::|||||::.|.
pombe  2509 ----------------------------------------------------LLEGIGISLVERN 2521

  Fly  3384 PCEEIMFISLDHINCDIVQSALENSLDLNIAYIQIDNQLLDAVSPIALH--------TQTSNDLE 3440
             .:|:.:::...||.....|.|..:..|::.:|||||||...:.||.|:        |...|.|.
pombe  2522 -TQELAYLTFHGINLFFTDSHLIRTFKLDVRWIQIDNQLYGGIYPIILYPSILSQEDTMNDNSLL 2585

  Fly  3441 ETQNAVVLKLKMLPSPNKNAIIFKYLTLDLKPSTASLEEKLILKVASFLGYGKINRQNLSVQYQF 3505
            .|.:::|..:|   :........||.|:.|:..|..::|........::        ..||....
pombe  2586 PTFHSMVAVVK---NDTYGVTYVKYATILLQELTIEIDEDFAFAALEYI--------KDSVPRSK 2639

  Fly  3506 ENT----DDKPFL------QDMKRYYFENLSIGATQVRLSAFTSSKL------PVELHET----K 3550
            .||    ||...|      .|:| .|||.|::..|::.||...:.::      .|..|..    .
pombe  2640 RNTGKMFDDSLELVPENLGNDLK-VYFEVLNLQPTEMHLSFVRTERINNTDGTVVSSHNPFVFFV 2703

  Fly  3551 KALGLTLIKFEDALIELDR-YSDKLHFETMDVYRKELKKHYINQVKWHAAAILGSVDFLGNPLGF 3614
            ..|.:.:....||.:.|:. ..|..|.....:: :.:|.||..::......|:||.||||||:|.
pombe  2704 NVLSMAIGNINDAPVRLNALLMDNAHVSLRRLF-ELVKNHYSQELLSQVHKIVGSADFLGNPVGL 2767

  Fly  3615 ANDLSEGVSGLIF---------EGSVK----------SLVKNVTHGISNSTAKLTETLSDSLGKV 3660
            ...::.|.:.:.:         |||.:          |.:|....||::|.:|:|.|:|.||..:
pombe  2768 FTTITSGFADIFYEPFHGFILNEGSYELGIGFAKGTASFIKKAVFGITDSISKVTGTISRSLSVI 2832

  Fly  3661 VLDDHDNETRQRILELQSNTSGGHL----AAGLKGLGFGLLGGVTSIVRHTYDGATSDGVPGFLS 3721
            .||. ..::|:|...:::...  |:    .||...|..|:..||..:......||..:|:||.:.
pombe  2833 TLDP-KFQSRRRAARIRNRPV--HILYGVTAGAASLYTGVRSGVRGLALQPIIGARRNGLPGLVK 2894

  Fly  3722 GLGKGLVGTVTKPIIGVLDLASETASAVRETSRDSHRNAPERKRLPRCVTGAPGGLLPLYSNRQS 3786
            ||||||||..|||::|:.|.||..:...|.|:........|:.||.|.:  :..|::..:..|::
pombe  2895 GLGKGLVGFTTKPLVGLFDFASSISEGARNTTTVFDERHIEKLRLSRLM--SDDGVVYPFQLREA 2957

  Fly  3787 KGQQYL-YLINQKNFSEKIISYEPNLWSDKEARLRLLVSTEYVRIFSLSDANPTIMFECHVSEI 3849
            .||.:| :|.|.:.|.:   .|:.::..:.    ::||.....||..:.........|.|:|::
pombe  2958 LGQYWLKHLDNGRYFKD---FYKAHIIIEN----KVLVILTNNRILFVQPQQLNCKKEIHLSKV 3014

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vps13D	NP_729825.2	Chorein_N	4..112	CDD:315323	37/109 (34%)
		VPS13	147..368	CDD:318996	56/236 (24%)
		VPS13_mid_rpt	<656..837	CDD:318998	39/210 (19%)
		VPS13	<2039..>2694	CDD:330393	109/693 (16%)
		SHR-BD	2836..3113	CDD:310922	78/332 (23%)
		VPS13	<3346..3802	CDD:330393	132/508 (26%)
vps13a	NP_001342827.1	MRS6	1..2503	CDD:227376	646/3566 (18%)
		MRS6	<2316..3068	CDD:227376	197/906 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	58	1.000	Domainoid score	I3086
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR16166
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1642
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.040