DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Klc and KLCR2

DIOPT Version :9

Sequence 1:NP_001261780.1 Gene:Klc / 39445 FlyBaseID:FBgn0010235 Length:508 Species:Drosophila melanogaster
Sequence 2:NP_001326010.1 Gene:KLCR2 / 822420 AraportID:AT3G27960 Length:663 Species:Arabidopsis thaliana


Alignment Length:335 Identity:80/335 - (23%)
Similarity:134/335 - (40%) Gaps:55/335 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly   187 RTLHNLVIQYASQGRYEVAVPLCKQALEDLERTSGHDHPDVATMLNILALVYRDQNKYKEAANLL 251
            |.|..|:..  ::|.||||  |....|..:..:|.:...|||.:...:...|....::.||....
plant   332 RKLMGLICD--AKGDYEVA--LEHYVLASMAMSSQNHREDVAAVDCSIGDAYMSLARFDEAIFAY 392

  Fly   252 NDALSIRGKTLGENHPAVAATLNNLAVLYGKRGKYKDAEPLCKRALEIREK-VLGKDHPDVAKQL 315
            ..||::..:..||.|.:||.....||.||.|.||.:|::..|:.||:|..| ..|....:||...
plant   393 QKALAVFKQGKGETHSSVALVYVRLADLYNKIGKTRDSKSYCENALKIYLKPTPGTPMEEVATGF 457

  Fly   316 NNLALLCQNQGKYDEVEKYYQRALDIYESKLGPDDPNVAKTKNNLAG--------CYLKQGRYTE 372
            ..::.:.|:..:.|:..|..:|||.||        .|....:|.:||        .|: .|.|:|
plant   458 IEISAIYQSMNELDQALKLLRRALKIY--------ANAPGQQNTIAGIEAQMGVVTYM-MGNYSE 513

  Fly   373 AEILYKQVLTRAHE-------------REFGAIDSKNKPIWQVAEEREEHK-FDNRENTPYGEYG 423
            :..::|..:::...             .:.|....:...|.:.|:..||.| ...:|..||    
plant   514 SYDIFKSAISKFRNSGEKKTALFGIALNQMGLACVQRYAINEAADLFEEAKTILEKECGPY---- 574

  Fly   424 GWHKAAKVDSPTVTTTLKNLGALYRRQGMFEAAETLEDCAMRSKKEAYDLA------KQTKLSQL 482
                     .|.......||...|...|..:.|..:.:..:.:::|....|      ::.:|:.|
plant   575 ---------HPDTLAVYSNLAGTYDAMGRLDDAIEILEYVVGTREEKLGTANPEVEDEKQRLAAL 630

  Fly   483 LTSNEKRRSK 492
            |....:.|||
plant   631 LKEAGRGRSK 640

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
KlcNP_001261780.1 TPR_12 185..258 CDD:315987 19/70 (27%)
TPR repeat 187..214 CDD:276809 9/26 (35%)
TPR_12 226..302 CDD:315987 25/75 (33%)
TPR repeat 228..256 CDD:276809 5/27 (19%)
TPR_12 269..344 CDD:315987 26/75 (35%)
TPR repeat 270..298 CDD:276809 11/27 (41%)
TPR_12 310..384 CDD:315987 19/81 (23%)
TPR repeat 311..341 CDD:276809 8/29 (28%)
TPR_12 353..469 CDD:315987 23/137 (17%)
TPR repeat 354..381 CDD:276809 8/34 (24%)
KLCR2NP_001326010.1 TPR_12 153..229 CDD:315987
TPR repeat 203..228 CDD:276809
TPR 239..486 CDD:223533 48/165 (29%)
TPR repeat 246..271 CDD:276809
TPR repeat 286..313 CDD:276809
TPR repeat 318..364 CDD:276809 11/35 (31%)
TPR_12 367..443 CDD:315987 25/75 (33%)
TPR repeat 373..405 CDD:276809 5/31 (16%)
TPR_12 409..484 CDD:315987 24/74 (32%)
TPR repeat 410..440 CDD:276809 13/29 (45%)
TPR repeat 454..482 CDD:276809 6/27 (22%)
TPR repeat 488..523 CDD:276809 8/35 (23%)
TPR_12 494..569 CDD:315987 13/75 (17%)
TPR repeat 528..566 CDD:276809 6/37 (16%)
TPR_12 538..603 CDD:315987 15/77 (19%)
TPR repeat 579..603 CDD:276809 5/23 (22%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1840
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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