DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Klc and appbp2

DIOPT Version :9

Sequence 1:NP_001261780.1 Gene:Klc / 39445 FlyBaseID:FBgn0010235 Length:508 Species:Drosophila melanogaster
Sequence 2:XP_002933870.1 Gene:appbp2 / 100487715 XenbaseID:XB-GENE-951373 Length:585 Species:Xenopus tropicalis


Alignment Length:341 Identity:73/341 - (21%)
Similarity:129/341 - (37%) Gaps:92/341 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   103 QQKFQASEQLVAQLEEEKKHLEFMASVKKYDENQEQDDACDKSRTDPVVELFPDEENEDRHNMSP 167
            :::|:.:|||:       ||..::|                                  |.|..|
 Frog   259 KREFKKAEQLI-------KHAVYLA----------------------------------RENFGP 282

  Fly   168 TPP----------------SQFANQTSGYEIPARLR------------TLH------NLVIQYAS 198
            ..|                .......:.|:....:|            |.|      :.|.||:|
 Frog   283 KHPKYSDALLDYGFYLLNVDNICQSVAIYQTALDIRQSVFGGKNIHVATAHEDLAYSSYVHQYSS 347

  Fly   199 QGRYEVAVPLCKQALEDLERTSGHDHPDVATMLNILALVYR-----------DQNKYKEAANLLN 252
             |:::.|:...::|:|.:......||..:|:...:.||:..           :|...:||.:|..
 Frog   348 -GKFDNALFHAERAIEIITHILPEDHLLLASSKRVKALILEEIAIDCHNKETEQKLLQEAHDLHL 411

  Fly   253 DALSIRGKTLGENHPAVAATLNNLAVLYGKRGKYKDAEPLCKRALEIREKVLGKDHPDVAKQLNN 317
            .:|.:..|..||.:...|....||..||....|:|:||.:..:|::|:|::||::..:||..:.:
 Frog   412 SSLQLAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKEQLLGQEDYEVALSVGH 476

  Fly   318 LALLCQ-NQGKYDEVEKYYQRALDIYESKLGPDDPNVAKTKNNLAGCYLKQGRYTEAEILYKQVL 381
            ||.|.. :..:|:..||.|.|::.|.:...|.....:......|...|...|.| |....|..:|
 Frog   477 LASLYNYDMSQYENAEKLYLRSIAIGKKLFGEGYSGLEYDYRGLIKLYNSVGNY-EKVFEYHNIL 540

  Fly   382 ---TRAHEREFGAIDS 394
               .|..:|:|...|:
 Frog   541 ANWNRLRDRQFSVTDA 556

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
KlcNP_001261780.1 TPR_12 185..258 CDD:315987 21/101 (21%)
TPR repeat 187..214 CDD:276809 10/44 (23%)
TPR_12 226..302 CDD:315987 22/86 (26%)
TPR repeat 228..256 CDD:276809 7/38 (18%)
TPR_12 269..344 CDD:315987 25/75 (33%)
TPR repeat 270..298 CDD:276809 10/27 (37%)
TPR_12 310..384 CDD:315987 19/77 (25%)
TPR repeat 311..341 CDD:276809 10/30 (33%)
TPR_12 353..469 CDD:315987 11/45 (24%)
TPR repeat 354..381 CDD:276809 6/26 (23%)
appbp2XP_002933870.1 TPR_12 290..363 CDD:315987 11/73 (15%)
TPR_12 427..504 CDD:315987 25/76 (33%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.