Protein Alignment Ptp69D and pyp2

DIOPT Version :10

• Sequence 1: NP_524048.2
• Gene: Ptp69D / 39443
• FlyBaseID: FBgn0014007
• Length: 1462
• Species: Drosophila melanogaster
• Sequence 2: NP_594899.1
• Gene: pyp2 / 2542200
• PomBaseID: SPAC19D5.01
• Length: 711
• Species: Schizosaccharomyces pombe
• Alignment Length: 787
• Identity: 188/787 - (23%)
• Similarity: 286/787 - (36%)
• Gaps: 289/787 - (36%)

  Fly   499 IDEPHHKTLYESVSPNTN-------------YTVTVSAITRHKKNGEPATGSCLMPVSTPDAIGR 550
            :||.:...||:|.....|             |:..:..::    ||..|..|     |.||||..
pombe    76 LDEINAIFLYDSSMAGMNRIYDLVQKFRRGGYSKKIYLLS----NGFEAFAS-----SHPDAIVS 131

  Fly   551 TMWSKVNLDSKYVL----KLYLPKISERNG---------------------PICCYRLYLVRINN 590
            |...|.::..|..:    ||.:..:|:.:.                     |:|...:.....:.
pombe   132 TEMVKESVPYKIDINENCKLDILHLSDPSAVSTPISPDYSFPLRVPINIPPPLCTPSVVSDTFSE 196

  Fly   591 --DNKELP-----------DPEKLNIATYQEVHSDNVT-RSSAYIAEMISSKYF--RPEIFLG-- 637
              .:.|.|           .|...::.:.|.::...:: .:||:.|||   .||  .|.|...
pombe   197 FASHAEYPGFSGLTPFSIHSPTASSVRSCQSIYGSPLSPPNSAFQAEM---PYFPISPAISCASS 258

  Fly   638 -----DEKRFSENNDIIRDNDEICRKCLEGTPFLRKPEIIHIPPQGSLSN----SDSELPILSEK 693
                 ||::          |..|.....:.||  .:|.:..:|...|.:|    |.|.:...|
pombe   259 CPSTPDEQK----------NFFIVGNAPQQTP--ARPSLRSVPSYPSSNNQRRPSASRVRSFS-- 309

  Fly   694 DNLIKGAN-----LTEHALKILESK-LRDKRNAVTSDENPILSAVNPNVPLHDSSRDVFDGEIDI 752
             |.:|.:|     |::.:|:|:..| ::...||.....:.:.|.:.|:|.| .::||
pombe   310 -NYVKSSNVVNPSLSQASLEIIPRKSMKRDSNAQNDGTSTMTSKLKPSVGL-SNTRD-------- 364

  Fly   753 NSNYTGFLEIIVRDRNNALMAYSKYFDIITPATEAEPIQSLNNMDYYLSIGVKAGAVLLGVILVF 817
                                           |.:...::..|...:
pombe   365 -------------------------------APKPGGLRRANKPCF------------------- 379

  Fly   818 IVLWVFHHKKTKNELQGEDTLTLRDSLSRALFGRRNHNHSHFITSGNHKG-FDAGPIHR------ 875
                   :|:||.                ::|.:.|            || |...|...
pombe   380 -------NKETKG----------------SIFSKEN------------KGPFTCNPWGAKKVSPP 409

  Fly   876 -----LDLENA---YKNRHKDTDYGFLREYEMLPNRFSDRTTKNSDLKENAC------------K 920
                 .||..|   ||.:.       |.|.||      .|:...:|.|.:.|            |
pombe   410 PCEVLADLNTASIFYKFKR-------LEEMEM------TRSLAFNDSKSDWCCLASSRSTSISRK 461

  Fly   921 NRYPDIKAYDQTRVKLAVINGLQTTDYINANFV-IGYKERKKFICAQGPMESTIDDFWRMIWEQH 984
            |||.||..||:|||:|||..|  .:|||||:.: :|   .||:|..|.|...|:.|||.|:|...
pombe   462 NRYTDIVPYDKTRVRLAVPKG--CSDYINASHIDVG---NKKYIACQAPKPGTLLDFWEMVWHNS 521

  Fly   985 --LEIIVMLTNLEEYNKAKCAKYWPEKVFDTKQFGDILVKFAQERKTGDYIERTLNVSKNKANVG 1047
              ..:|||||||.|....||::|||    |.|.....|             |..|.:|..|....
pombe   522 GTNGVIVMLTNLYEAGSEKCSQYWP----DNKDHALCL-------------EGGLRISVQKYETF 569

  Fly  1048 EE---------EDR-----RQITQYHYLTWKDFMAP--EHPHGIIKFIRQINSVYSLQRGPILVH 1096
            |:         .|:     :.|..:...||.|...|  |...|||:.|.::.:     .||:.||
pombe   570 EDLKVNTHLFRLDKPNGPPKYIHHFWVHTWFDKTHPDIESITGIIRCIDKVPN-----DGPMFVH 629

  Fly  1097 CSAGVGRTGTLVALDSLIQQLEE--------EDSVS-IYNTVCDLRHQRNFLVQSLKQYIFLYRA 1152
            ||||||||||.:|:|.::|..:.        |||.. |:|.|..||.||..:||:.:|:.|||..
pombe   630 CSAGVGRTGTFIAVDQILQVPKNILPKTTNLEDSKDFIFNCVNSLRSQRMKMVQNFEQFKFLYDV 694

  Fly  1153 L--LDTG 1157
            :  |::|
pombe   695 VDYLNSG 701

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptp69D	NP_524048.2	Ig_3	35..114	CDD:464046
		Ig_3	134..216	CDD:464046
		fn3	237..321	CDD:394996
		FN3	<300..>524	CDD:442628	7/37 (19%)
		PTPc	892..1155	CDD:214550	105/304 (35%)
		PTPc	1186..1449	CDD:214550
pyp2	NP_594899.1	DSP_MapKP	4..129	CDD:238723	14/61 (23%)
		PHA03247	<159..304	CDD:223021	26/159 (16%)
		PTP_fungal	486..693	CDD:350509	80/231 (35%)