Protein Alignment Ptp69D and Ptpra

DIOPT Version :10

• Sequence 1: NP_524048.2
• Gene: Ptp69D / 39443
• FlyBaseID: FBgn0014007
• Length: 1462
• Species: Drosophila melanogaster
• Sequence 2: XP_006235068.1
• Gene: Ptpra / 25167
• RGDID: 3450
• Length: 805
• Species: Rattus norvegicus
• Alignment Length: 823
• Identity: 273/823 - (33%)
• Similarity: 425/823 - (51%)
• Gaps: 81/823 - (9%)

  Fly   671 IIHIPPQGSLSNSDSELPILSEKDNLIKGANLTEHALKILESKLRDKRNAVTS-DENPILSAVNP 734
            :|||    |.:|:.:..|.|. ...||| .:.||.|.:  |:|..:..::|.| ...|..|   |
  Rat    14 LIHI----SANNTTTVSPSLG-TTRLIK-TSTTESAKE--ENKTSNSTSSVISLSVTPTFS---P 67

  Fly   735 NVPL--------HDSSRDVFDGEIDINSNYTGFLEIIVRDRNNALMAYSKYFDI---------IT 782
            |:.|        :.|..|  :|.....|..:|...|.........:..:::.|.         .|
  Rat    68 NLTLEPTYVTTVNSSHSD--NGTKRAASTESGGTTISPNGTYGTWLTDNQFTDARTEPWEGNSST 130

  Fly   783 PATEAEPIQSLNNMDY--------YLSIGVKAGAVLLGVILVFIVLWVFHHKKTKNELQGEDTLT 839
            .||..|......|.|.        .:::.|...::|: ::.:.|||::...||.|.  .|..:.:
  Rat   131 AATTPETFPPAGNSDSKDRRDETPIIAVMVALSSLLV-IVFIIIVLYMLRFKKYKQ--AGSHSNS 192

  Fly   840 LRDSLSRA---------LFGRRNHNHSHFITSGNHKGFDAGPIHRLDLENAYKNRHKDTDYGFLR 895
            .|.|..|.         |..|.        .|.|.| |...|:.:  ||.....|..|.:..|..
  Rat   193 FRLSNGRTEDVEPQSVPLLARS--------PSTNRK-FPPLPVDK--LEEEINRRMADDNKLFRE 246

  Fly   896 EYEMLPNRFSDRTTKNSDLKENACKNRYPDIKAYDQTRVKLAVINGLQTTDYINANFVIGYKERK 960
            |:..||......|.:.:..:||..||||.:|..||.:||.|..:.|:..:|||||:|:.||:|:.
  Rat   247 EFNALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGYQEKN 311

  Fly   961 KFICAQGPMESTIDDFWRMIWEQHLEIIVMLTNLEEYNKAKCAKYWPEKVFDTKQFGDILVKFAQ 1025
            |||.||||.|.|::|||||||||:...|||:|||:|..:.|||:|||::...|  :|::.|....
  Rat   312 KFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQGCWT--YGNVRVSVED 374

  Fly  1026 ERKTGDYIERTLNVSKNKANVGEEEDR---RQITQYHYLTWKDFMAPEHPHGIIKFIRQINSVYS 1087
            .....||..|...:.:    ||:..:|   |.|||:|:.:|.||..|..|.|::||::::.:...
  Rat   375 VTVLVDYTVRKFCIQQ----VGDVTNRKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNP 435

  Fly  1088 LQRGPILVHCSAGVGRTGTLVALDSLIQQLEEEDSVSIYNTVCDLRHQRNFLVQSLKQYIFLYRA 1152
            ...|.|:||||||||||||.|.:|:::..:..|..|.:|..|..:|.||..:||:..||:|:|:|
  Rat   436 QYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHSERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQA 500

  Fly  1153 LLDTGTFGNTDICIDTMASAIESLKRK-PNEGKCKLEVEFEKLLATADEISKSCSVGENEENNMK 1216
            ||:...:|:|::.:.::.:.::.:..| |......||.||:||.:...:..| ...|....|..|
  Rat   501 LLEHYLYGDTELEVTSLDTHLQKIYNKIPGTSNNGLEEEFKKLTSIKIQNDK-MRTGNLPANMKK 564

  Fly  1217 NRSQEIIPYDRNRVILTPLPMRENSTYINASFIEGYDNSETFIIAQDPLENTIGDFWRMISEQSV 1281
            ||..:||||:.||||:......||:.|:|||||:||...:::|.:|.||.:||.||||||.|...
  Rat   565 NRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQKDSYIASQGPLLHTIEDFWRMIWEWKS 629

  Fly  1282 TTLVMISEIGD-GPRKCPRYW-ADDEVQYDHILVKYVHSESCPYYTRREFYVTNCKIDDTLKVTQ 1344
            .::||::|:.: |..||.:|| :|..|.|..|.|:....|.|..||.|:..|||.:.:.:.::.|
  Rat   630 CSIVMLTELEERGQEKCAQYWPSDGLVSYGDITVELKKEEECESYTVRDLLVTNTRENKSRQIRQ 694

  Fly  1345 FQYNGWPTVDGEVPEVCRGIIELVDQAYNHYKNNKNSGCRSPLTVHCSLGTDRSSIFVAMCILVQ 1409
            |.::|||.|.  :|...:|:|.::...   .|..:.|| ..|:|||||.|..|:..|.|:..:::
  Rat   695 FHFHGWPEVG--IPSDGKGMINIIAAV---QKQQQQSG-NHPITVHCSAGAGRTGTFCALSTVLE 753

  Fly  1410 HLRLEKCVDICATTRKLRSQRTGLINSYAQYEFLHRAIINYSD 1452
            .::.|..:|:..|.:.||.||..::.:..||||.::.:..|.|
  Rat   754 RVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYID 796

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptp69D	NP_524048.2	Ig_3	35..114	CDD:464046
		Ig_3	134..216	CDD:464046
		fn3	237..321	CDD:394996
		FN3	<300..>524	CDD:442628
		PTPc	892..1155	CDD:214550	111/265 (42%)
		PTPc	1186..1449	CDD:214550	97/264 (37%)
Ptpra	XP_006235068.1	PHA03255	<18..177	CDD:165513	37/168 (22%)
		R-PTPc-A-1	217..512	CDD:350469	122/303 (40%)
		R-PTPc-A-2	566..793	CDD:350471	86/232 (37%)