DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptp69D and F55H12.5

DIOPT Version :9

Sequence 1:	NP_524048.2	Gene:	Ptp69D / 39443	FlyBaseID:	FBgn0014007	Length:	1462	Species:	Drosophila melanogaster
Sequence 2:	NP_492395.2	Gene:	F55H12.5 / 172700	WormBaseID:	WBGene00010136	Length:	287	Species:	Caenorhabditis elegans

Alignment Length:	333	Identity:	69/333 - (20%)
Similarity:	131/333 - (39%)	Gaps:	99/333 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   859 FITS-GNHKGFDAGPIHRLDLENAYKNRHKDTDYGFLREYEMLPNRFSDRTTKNSDLKENACKNR 922
            ||.| .|.|.|:||      :...||..:.::...|        |.|  ::.|:.:..||
Worm    42 FINSKTNSKSFEAG------VAEFYKETYLESPTFF--------NYF--KSPKDKNFSEN----- 85

  Fly   923 YPDIKAYDQTRVKLAVINGLQTTDYINANFVIGYKERKKFICAQGPME-STIDDFWRMIWEQHLE 986
               :..||.|||   ::.|:   ||.:|::|.|.|. .::|.||.|.: |...||::::.....|
Worm    86 ---VWLYDATRV---IVPGV---DYYHASWVDGLKP-NQYILAQAPRDASAAKDFFKLLEHVKAE 140

  Fly   987 IIVMLTNLEEYNKAKCAKYWPEKVFDTKQFGDILVKFAQERKTG--DYIERTLNVSKNKANVGEE 1049
            .:::....:|::.|..||:                    |:.||  |::...:          .:
Worm   141 GLIVAEGADEFSSAITAKF--------------------EKGTGKNDFVSTAV----------IK 175

  Fly  1050 EDRRQITQYHYLTWKDFMAPEHPHGIIKFIRQINSVYSLQR--------GPILVHCSAGVGRTGT 1106
            |:...:....:..|.:      |...|    :||.:....|        ||:::.|..|..::|.
Worm   176 ENGLHLKAIKFCRWAE------PLSAI----EINDMLEKSRKYLGCPLKGPLVIVCKDGAAKSGL 230

  Fly  1107 LVALDSLIQQLEEEDSVSIYNTVCDLRHQRNFLVQSLKQYIFLYRALLDTGTFGNTDICIDTMAS 1171
            :..:|:...:|              ::|.:.....::||..|:.....|  ||.:.|:.|:::..
Worm   231 VAFIDTEADRL--------------MKHGKAKHTDTIKQIRFMRSNTFD--TFDSYDLGINSLIE 279

  Fly  1172 AIESLKRK 1179
            .....|:|
Worm   280 LCNRYKKK 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptp69D	NP_524048.2	IG_like	139..233	CDD:214653
		Ig	150..221	CDD:143165
		fn3	237..321	CDD:278470
		FN3	339..432	CDD:238020
		FN3	439..535	CDD:238020
		PTPc	892..1155	CDD:214550	52/273 (19%)
		PTPc	920..1155	CDD:238006	46/245 (19%)
		PHA02694	<1121..1206	CDD:177476	11/59 (19%)
		PTPc	1186..1449	CDD:214550
		PTPc	1216..1449	CDD:238006
F55H12.5	NP_492395.2	PTPc	74..270	CDD:214550	53/268 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG4228
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810