Protein Alignment mirr and irx5a

DIOPT Version :9

• Sequence 1: NP_001261778.1
• Gene: mirr / 39441
• FlyBaseID: FBgn0014343
• Length: 682
• Species: Drosophila melanogaster
• Sequence 2: NP_001038692.1
• Gene: irx5a / 573346
• ZFINID: ZDB-GENE-010716-2
• Length: 446
• Species: Danio rerio
• Alignment Length: 562
• Identity: 169/562 - (30%)
• Similarity: 221/562 - (39%)
• Gaps: 190/562 - (33%)

  Fly    34 PQ----SPPSTLPTLACPAAQPLSAPGIAGPGHSGMVTSTVPPGARSTSPCGPSAGLPALSLVGA 94
            ||    .|.::|...:|||   .|...|:||....:..|:      |.|...|.||..|.:   :
Zfish     4 PQGYLYQPSASLALYSCPA---YSTSVISGPRTEELGRSS------SGSAFAPYAGSTAFT---S 56

  Fly    95 PPPGPHSSAPGGAPAPGAGNPPNRCCDTGRTIYTDPVSGQTICSCQYDMLNYQRLAAAGGVPLGV 159
            ..||.:|..|..|.|..|..            :|..||.      .||
Zfish    57 ASPGYNSHLPYSADAAAAAT------------FTSYVSS------PYD----------------- 86

  Fly   160 YPEGMSAYLSGIAADQPPFYANPAGIDLKENLVAGASPWPYPSMYHPYDAAFAGYPFNSYGMDLN 224
            :..||:..:.                                  ||||.|....||   ||   :
Zfish    87 HTTGMAGSIG----------------------------------YHPYAAPLGSYP---YG---D 111

  Fly   225 GARRKNATRETTSTLKAWLNEHKKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMT 289
            .|.||||||:.|:|||||||||:||||||||||||||||||||||||||||||||||||||||||
Zfish   112 PAYRKNATRDATATLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMT 176

  Fly   290 WEPRNRVDD--DDANID----DDDDKNTEDNDLLDAKDSGVGSTDDKDRSGRL---GDMMTDRPG 345
            |.||||.:|  :|.|||    |||:.|         |.:..|.:.|.:...:|   |::..||..
Zfish   177 WTPRNRSEDEEEDENIDLEKNDDDEPN---------KPTDKGDSTDTEADHKLINPGEIPCDRFK 232

  Fly   346 ESNNSE-----WSESRPGSPNGSPDLYDRPGSMPPGAHPLFHPAALHHHFRPPAGSPPDIAAYHH 405
            :..:|:     .::|.........||                   |....:|...||..:    .
Zfish   233 DETHSKDLDPPLTDSELKEAEERTDL-------------------LAEQAKPTTSSPSVL----Q 274

  Fly   406 HQQQLLQQ-------HQQAQQNSLQTAV----GGTAKPRIWSLADMAS-----KDSKDSSSGAKD 454
            ....|:.|       |..:..||..|:|    ....||::||||::|:     |.|.::|..|..
Zfish   275 RGSDLITQEKPSEPGHAASTGNSNVTSVIHSPPSAPKPKLWSLAEIATSSDRCKGSSEASQAAGL 339

  Fly   455 NHPELPPAHPGFYGHPGQQPSPGKILSPLAARIPNYSPYVRPDLYRGFYGPAAAHLGAPTQEFLE 519
            :...:..:        ...|:......||    ||.:...||..|...:.|...:..
Zfish   340 SQSTVIAS--------AASPTRSSPQCPL----PNNTVLSRPIYYTSPFYPGYTNYS-------- 384

  Fly   520 HQRTFGASLAAHNGPLGMNPLLWKAAVSGAANGHHFAPLSLT 561
               |||...::|    |.|       .|..|   ||..||.|
Zfish   385 ---TFGHLHSSH----GTN-------TSSTA---HFNGLSQT 409

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mirr	NP_001261778.1	Homeobox_KN	242..281	CDD:283551	37/38 (97%)
irx5a	NP_001038692.1	Homeobox_KN	129..168	CDD:283551	37/38 (97%)
		IRO	307..324	CDD:214716	7/16 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	86	1.000	Domainoid score	I8040
eggNOG	1	0.900	-	-		E1_KOG0773
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR11211
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5654
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	7	6.900