Protein Alignment mirr and MEIS3

DIOPT Version :9

• Sequence 1: NP_001261778.1
• Gene: mirr / 39441
• FlyBaseID: FBgn0014343
• Length: 682
• Species: Drosophila melanogaster
• Sequence 2: XP_024307380.1
• Gene: MEIS3 / 56917
• HGNCID: 29537
• Length: 509
• Species: Homo sapiens
• Alignment Length: 448
• Identity: 89/448 - (19%)
• Similarity: 133/448 - (29%)
• Gaps: 190/448 - (42%)

  Fly    10 ICLVMNAVSTHLATSSPNTPPTNAPQSPPSTLPTLACPAAQPLSAPGIAGPGHSGMVTSTVP--- 71
            :||.:......|...||:..|      |..|||:|  |...|....||:....|.:.|...|
Human    22 VCLSLCLCHCLLTPLSPSLFP------PSQTLPSL--PLGPPAHMSGISAWTGSSLPTEAAPGDL 78

  Fly    72 -----PGARSTSP------------CGPSAGLPALSLVGAPPPGPHSSAPGGAPAPGAGNPPNRC 119
                 .|:.:..|            .||:|      |...|...|....|.|...|....||...
Human    79 EGFKLGGSDTWGPQYDELPHYPGIVDGPAA------LASFPETVPAVPGPYGPHRPPQPLPPGLD 137

  Fly   120 CDTGRTIYTDPVSGQTIC--------SCQYDMLNYQRLAAAG-GVPLG-------VYPEGMSAYL 168
            .| |.....|.:.|..:.        .|:....:.:..|.|| |.|.|       .:.|.::|:.
Human   138 SD-GLKREKDEIYGHPLFPLLALVFEKCELATCSPRDGAGAGLGTPPGGDVCSSDSFNEDIAAFA 201

  Fly   169 SGIAADQPPFYANP-------AGI--------------DLKENL-------VAGASP-------- 197
            ..:.:::|.|.:||       ..|              ||.:|.       :.|..|
Human   202 KQVRSERPLFSSNPELDNLMIQAIQVLRFHLLELEKVHDLCDNFCHRYITCLKGKMPIDLVIEDR 266

  Fly   198 ----------WP--YPSM----------YHPYDAAFAGYPFNSYG-------------------- 220
                      :|  .||:          :....:...|.|..|.|
Human   267 DGGCREDFEDYPASCPSLPDQNNMWIRDHEDSGSVHLGTPGPSSGGLASQSGDNSSDQGDGLDTS 331

  Fly   221 ----------MDLNGARRKNATR-----ETTSTLKAWLNEH------------------------ 246
                      .||:..||:|..|     ..|:.::|||.:|
Human   332 VASPSSGGEDEDLDQERRRNKKRGIFPKVATNIMRAWLFQHLSRRSEAPVLPDVCLGLGSPSPGP 396

  Fly   247 ----------------------KKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRL 282
                                  .::|||::.:|..||..|.:|:.||:.||.|||||:
Human   397 RWARPWGSDCGRPGRQSDSCWWLQHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRI 454

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mirr	NP_001261778.1	Homeobox_KN	242..281	CDD:283551	18/84 (21%)
MEIS3	XP_024307380.1	Meis_PKNOX_N	184..267	CDD:318653	13/82 (16%)
		Homeobox_KN	417..453	CDD:310480	15/35 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0773
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900