Protein Alignment mirr and Irx5

DIOPT Version :9

• Sequence 1: NP_001261778.1
• Gene: mirr / 39441
• FlyBaseID: FBgn0014343
• Length: 682
• Species: Drosophila melanogaster
• Sequence 2: NP_001025215.1
• Gene: Irx5 / 498918
• RGDID: 1565518
• Length: 484
• Species: Rattus norvegicus
• Alignment Length: 585
• Identity: 183/585 - (31%)
• Similarity: 232/585 - (39%)
• Gaps: 199/585 - (34%)

  Fly    34 PQ----SPPSTLPTLACPAAQPLSAPGIAGPGHSGMVTSTVPPGARSTSPCGPSAGLPALSLVGA 94
            ||    .|.::|...:|||   .|...|:||....:..|:      |.|...|.||..|.:   |
  Rat     4 PQGYLYQPSASLALYSCPA---YSTSVISGPRTDELGRSS------SGSAFSPYAGSTAFT---A 56

  Fly    95 PPPGPHSSAPGGAPAPGAGNPPNRCCDTGRTIYTDPVSGQTICSCQYDMLNYQRLAAAGGVPLGV 159
            |.||.:|....||                     ||.:                 |||...
  Rat    57 PSPGYNSHLQYGA---------------------DPAA-----------------AAAAAF---- 79

  Fly   160 YPEGMSAYLSGIAADQPPFYANPAGIDLKENLVAGASPWPYPSMYHPYDAAFAGYPFNSYGMDLN 224
                  :|: |...|..|..|...|                   ||||.|....||   ||   :
  Rat    80 ------SYV-GSPYDHTPGMAGSLG-------------------YHPYAAPLGSYP---YG---D 112

  Fly   225 GARRKNATRETTSTLKAWLNEHKKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMT 289
            .|.||||||:.|:|||||||||:||||||||||||||||||||||||||||.|||||||||||||
  Rat   113 PAYRKNATRDATATLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFVNARRRLKKENKMT 177

  Fly   290 WEPRNRVDDDDANIDDDDDKNTED-----NDLLDAKDSGVGSTDDKDRSG--RLGDMMT----DR 343
            |.||||.:|::...:.|.:||.||     .|..|.:....|.|:.|..:|  ||...::    :.
  Rat   178 WTPRNRSEDEEEEENIDLEKNDEDEPQKPEDKGDLEGPEAGGTEQKAAAGCERLQGPLSPAGKET 242

  Fly   344 PGESNNSEWSES-------------RPGSPN-------------------GSPDLYDRP--GSMP 374
            .|..::|::.||             |.|.|:                   |:|.....|  |.:|
  Rat   243 EGSLSDSDFKESPSEGRHDDLPRPPRAGEPSPAGPATARLAEDAGPHYPAGAPAPGPHPSAGELP 307

  Fly   375 PGAHPLFHPAALHHHFRPPAGSPPDIAAYHHHQQQLLQQHQQAQQNSLQTAVGGTAKPRIWSLAD 439
            ||:    ..:::.|...||...||.:                            .|||::||||:
  Rat   308 PGS----GGSSVIHSPPPPPPPPPAV----------------------------LAKPKLWSLAE 340

  Fly   440 MASKDSKDSSSGAKDNHPELPPAHPGFYGHPGQ-------QPSPGKILSPLA-ARIPNYSPYVRP 496
            :|:...|....|........||. ||..|  ||       .|:|....||.| ...|..:...||
  Rat   341 IATSSDKVKDGGGGSEGSPCPPC-PGPIG--GQTLGGSRASPAPAPARSPSAQCPFPGGTVLSRP 402

  Fly   497 DLYRGFYGPAAAHLGAPTQEFLEHQRTFGASLAAHNGPLGMNPLLWKAAVSGAANGHHFAPLSLT 561
            ..|...:.|...:.|           :|| .|..|.|| |..|.        |..|.||..|:.|
  Rat   403 LYYTAPFYPGYTNYG-----------SFG-HLHGHPGP-GPGPT--------AGPGSHFNGLNQT 446

  Fly   562  561
              Rat   447  446

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mirr	NP_001261778.1	Homeobox_KN	242..281	CDD:283551	36/38 (95%)
Irx5	NP_001025215.1	Homeobox_KN	130..169	CDD:283551	36/38 (95%)
		IRO	328..345	CDD:214716	8/44 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	86	1.000	Domainoid score	I7886
eggNOG	1	0.900	-	-		E1_KOG0773
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	182	1.000	Inparanoid score	I3876
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR11211
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	7	6.920