DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mirr and meis3

DIOPT Version :9

Sequence 1:	NP_001261778.1	Gene:	mirr / 39441	FlyBaseID:	FBgn0014343	Length:	682	Species:	Drosophila melanogaster
Sequence 2:	NP_001006782.1	Gene:	meis3 / 448474	XenbaseID:	XB-GENE-485337	Length:	453	Species:	Xenopus tropicalis

Alignment Length:	208	Identity:	54/208 - (25%)
Similarity:	88/208 - (42%)	Gaps:	60/208 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   222 DLNGARRKNATR-----ETTSTLKAWLNEHKKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRR 281
            ||:..:::|..|     ..|:.::|||.:|..:|||::.:|..||..|.:|:.||:.||.|||||
Frog   260 DLDRDKKRNKKRGIFPKVATNIMRAWLFQHLSHPYPSEEQKKQLAQDTGLTILQVNNWFINARRR 324

  Fly   282 LKKENKMTWEPRNRVDDDDANIDDDDDKNTEDNDLLDAKD-SGVG----STDDKDRSGRLGD--- 338
            :.:                              .::|..: :|.|    |.|.::..|.:.|
Frog   325 IVQ------------------------------PMIDQSNRTGQGGAPYSPDGQNMGGYVMDGQQ 359

  Fly   339 -MMTDRPG-ESNNSEWSESRPGSPNGSPDLYDRPGSMPPGAHPLFHPAALH-------HHFRP-- 392
             |....|| :....:::.:....|.|.|.....| ::||.:..|.|..:||       ||...
Frog   360 HMGIRPPGFQGIPGDYTAAPSTMPMGFPPAGYTP-AIPPHSAGLRHGPSLHSYLPGHPHHASMIL 423

  Fly   393 PAGSPPDIAAYHH 405
            |||:.|     ||
Frog   424 PAGTSP-----HH 431

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mirr	NP_001261778.1	Homeobox_KN	242..281	CDD:283551	18/38 (47%)
meis3	NP_001006782.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	33..64
		Meis_PKNOX_N	102..186	CDD:374576
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	192..272		3/11 (27%)
		Homeobox_KN	285..324	CDD:368670	18/38 (47%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000