Protein Alignment mirr and irx2a

DIOPT Version :10

• Sequence 1: NP_001261778.1
• Gene: mirr / 39441
• FlyBaseID: FBgn0014343
• Length: 682
• Species: Drosophila melanogaster
• Sequence 2: NP_957351.1
• Gene: irx2a / 394032
• ZFINID: ZDB-GENE-040426-1446
• Length: 432
• Species: Danio rerio
• Alignment Length: 571
• Identity: 172/571 - (30%)
• Similarity: 224/571 - (39%)
• Gaps: 219/571 - (38%)

  Fly    34 PQ----SPPSTLPTLACPAAQPLSAPGIAGPGHSGMVTSTVPPGARSTSPCGPSAGLPALSLVGA 94
            ||    .||.:|...:||.|.|.|..  .....||...|..|..|..|:           |..|.
Zfish     4 PQGYLYQPPGSLALYSCPLAAPRSED--LARSSSGSAFSPYPGSAAFTA-----------SANGF 55

  Fly    95 PPPGPHSSAPGGAPAPGAGNPPNRCCDTGRTIYTDPVSGQTICSCQYDMLNYQRLAAAGGVPLGV 159
            ..|.|:|                          |||.:|
Zfish    56 SSPLPYS--------------------------TDPATG-------------------------- 68

  Fly   160 YPEGMSAYLSGIAADQPPFYANPAGIDLKENLVAGASPWPYPSMYHPYDAAFAGYPFNSYGMDLN 224
            :|..|.:          |:.|:..|       :|||      ..||||.:  .|||:     .||
Zfish    69 FPSYMGS----------PYDAHTTG-------MAGA------ISYHPYGS--PGYPY-----QLN 103

  Fly   225 G-ARRKNATRETTSTLKAWLNEHKKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKM 288
            . |.||||||:.|:||||||.||:||||||||:||||||||||||||||||||||||||||||||
Zfish   104 DPAYRKNATRDATATLKAWLQEHRKNPYPTKGQKIMLAIITKMTLTQVSTWFANARRRLKKENKM 168

  Fly   289 TWEPRNRVDDDDANIDDDD--------DKNTEDNDLLDAKDSGVG-------------STDDKDR 332
            ||.|||:.:|:|.  ||.|        |||. ||....|:|.|:.             .:|.:..
Zfish   169 TWAPRNKSEDEDE--DDGDGERKDERTDKNM-DNSEASAEDEGISLHVDALTDHSCSVESDGEKV 230

  Fly   333 SGRLGDMMTDRPGESNN----SEWSESRPGSPNGSPDLYDRPGSMPPGAHPLFHPAALHHHFRPP 393
            :.|.||::.|...|..:    ::..|.|                 ..||.|           :|.
Zfish   231 TCRTGDLVCDSGAEIQDKCEATDLGEER-----------------QRGASP-----------KPV 267

  Fly   394 AGSP------PDIAAYHHHQQQLLQQHQQAQQNSLQTAVGG---TAKPRIWSLADMASKDSKDSS 449
            ..||      |.:.  |||:          :.::.:|.:.|   |.||::||||::|:.|.|
Zfish   268 TSSPLTGVEAPLLT--HHHR----------ENSTNKTCLDGQNQTVKPKLWSLAEIATSDPK--- 317

  Fly   450 SGAKDNHPELPPAHPGFYGHPGQQPSPGKILSPLAARIPNYSPYVRPDLYRGFYGPAAAHLGAP- 513
               :.|.|                  ||  :..|.:..|..||       .|...||.:.||.|
Zfish   318 ---QQNCP------------------PG--VGLLTSSAPGASP-------AGAVYPATSILGRPL 352

  Fly   514 --TQEFLEHQRTFGASLAAHNGPL-GMNPLLWKAAVSGAANGHHFAPLSLT 561
              |..|..:...:|     :..|| |...|.:.:|..|..:.....||..|
Zfish   353 YYTSPFYSNYTNYG-----NFSPLQGQGILRYNSAAEGLLHKQTGEPLIKT 398

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mirr	NP_001261778.1	Homeobox_KN	243..281	CDD:428673	34/37 (92%)
irx2a	NP_957351.1	Homeobox_KN	123..161	CDD:428673	34/37 (92%)