DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mirr and pknox2

DIOPT Version :9

Sequence 1:	NP_001261778.1	Gene:	mirr / 39441	FlyBaseID:	FBgn0014343	Length:	682	Species:	Drosophila melanogaster
Sequence 2:	NP_705940.1	Gene:	pknox2 / 386959	ZFINID:	ZDB-GENE-031118-112	Length:	474	Species:	Danio rerio

Alignment Length:	251	Identity:	57/251 - (22%)
Similarity:	89/251 - (35%)	Gaps:	69/251 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   169 SGIAADQPPFYANPAGI-DLKENLVAGASPWPYPSMYHPY-------DAAFAGYP-------FNS 218
            |||.....|...|...: .:...:|:|.      ::|.|.       .....|.|       .|.
Zfish   214 SGIVVPAGPLQQNNISMTTINSQVVSGG------TLYQPVAMVTSQGQVLTQGLPQGTIQIQNNQ 272

  Fly   219 YGMDLNG------ARRKN----ATRETTSTLKAWLNEHKKNPYPTKGEKIMLAIITKMTLTQVST 273
            ..:||:.      .:.||    ..:..|:.:::||.:|..:||||:.||..:|..|.:||.||:.
Zfish   273 VNLDLSSLLDGDDKKSKNKRGVLPKHATNIMRSWLFQHLMHPYPTEDEKRQIAAQTNLTLLQVNN 337

  Fly   274 WFANARRRL---------------KKENKMTWEPRNRVDDDD--ANIDDDDDKNTEDNDL----- 316
            ||.|||||:               .|:.|....|..|...|.  |.:......|..||.|
Zfish   338 WFINARRRILQPMLDASNPDPAPKAKKMKSQHRPTQRFWPDSIVAGVLQTHGTNNSDNSLGMDGL 402

  Fly   317 ----------------LDAKDSGVGSTDDKDRSGRLGDMMTDRPGESNNSEWSESR 356
                            |...|..:..|:::|......:.:.:...|.::.|...||
Zfish   403 QPLSSDSATLAMQQAMLGGTDDSMDGTEEEDEEEEEDEGLDEDDDEEDDEEHEASR 458

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mirr	NP_001261778.1	Homeobox_KN	242..281	CDD:283551	20/38 (53%)
pknox2	NP_705940.1	Meis_PKNOX_N	95..178	CDD:293102
pknox2	NP_705940.1	Homeobox_KN	306..345	CDD:283551	20/38 (53%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0773
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900