Protein Alignment mirr and Irx1

DIOPT Version :9

• Sequence 1: NP_001261778.1
• Gene: mirr / 39441
• FlyBaseID: FBgn0014343
• Length: 682
• Species: Drosophila melanogaster
• Sequence 2: NP_001100801.1
• Gene: Irx1 / 306659
• RGDID: 1309060
• Length: 480
• Species: Rattus norvegicus
• Alignment Length: 614
• Identity: 185/614 - (30%)
• Similarity: 242/614 - (39%)
• Gaps: 185/614 - (30%)

  Fly    40 TLPTLACPAAQPLSAPGIAGPGHSGMVTSTVPPGARS------TSPCGPSAGLPAL-SLVGA-PP 96
            :.|.|..|.....:.||..|....||:.:.....|.:      |:..|..||..|: |::|. ..
  Rat     2 SFPQLGYPQYLSAAGPGAYGGERPGMLAAAAAAAAAASSGRPGTAELGAGAGAAAVTSVLGMYAA 66

  Fly    97 PGPHSSAPGGAPAPGAGNPPNRCCDTGRTIYTDPVSGQTICSCQYDMLNYQRLAAAGGVPLGVYP 161
            .||::.||                                        ||
  Rat    67 AGPYAGAP----------------------------------------NY--------------- 76

  Fly   162 EGMSAYLSGIAADQPPFYANPAGIDLKENLVAGASPWPYPSMYHPYDAAFAGYPFN--SYGMDLN 224
               ||:|. .|||...|....:..:||:|      |..:|:.:..:... |.||:.  .||   :
  Rat    77 ---SAFLP-YAADLSLFSQMGSQYELKDN------PGVHPATFAAHTTP-AYYPYGQFQYG---D 127

  Fly   225 GARRKNATRETTSTLKAWLNEHKKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMT 289
            ..|.||||||:|||||||||||:||||||||||||||||||||||||||||||||||||||||:|
  Rat   128 PGRPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKVT 192

  Fly   290 WEPRNRVDDDDANIDDD---DDKNTEDNDLLDAKDSGVGSTDDKDRSGRLGDMMTDRPGESNNSE 351
            |..|::..:|.|....|   |.:..||::.:|.:...:...|::|     ||       :||..|
  Rat   193 WGARSKDQEDGALFGSDTEGDPEKAEDDEEIDLESIDIDQIDERD-----GD-------QSNEDE 245

  Fly   352 WSESRPGSPNG--SPDLYDRPGSMPPGAHPLF----HPAALHHHFRPPAGS---PPDIAAYHHHQ 407
              |.:..:|..  :|....|..|.|..|....    .|..|......|..:   .|..||.
  Rat   246 --EDKVEAPRARVAPPAPARDQSSPLSAAETLKSQDSPLGLAKEVSEPGSTRLLSPGAAAV---- 304

  Fly   408 QQLLQQHQQAQQNSLQTAVGGTAKPRIWSLADMASKDSKDSSSGAKDNHPELPPAHPGFYGHPGQ 472
                         .||.|  ..:||:|||||:.|:     |..||....|..|.:|...:|.|..
  Rat   305 -------------GLQGA--PHSKPKIWSLAETAT-----SPDGAPKASPPPPSSHASAHGPPSG 349

  Fly   473 QPSPGKILSPLAARIPNYSPYVRPDLYRGFYGPAAAHLGAPTQEFLEHQRTFGASLAAHNGPLGM 537
            .|    :..|  |.:|::..|             ..|:|    :|  ...|.||.| |....|.|
  Rat   350 SP----LQHP--AFLPSHGLY-------------TCHIG----KF--SNWTNGAFL-AQGSLLNM 388

  Fly   538 NPLLWKAAVSGAANGHHFAPLSLTTSGGSSGGQQVAPPPVASP-------------SASSSSSSM 589
            ...|..:|...|.:|.|.                .||||...|             |||||.:..
  Rat   389 RSFLGVSAPHAAPHGPHV----------------TAPPPPQLPVQVATGVLHGEKASASSSPALP 437

  Fly   590 GCDVVHIPTSSGQSAAQHMMGPISSNSTA 618
            ..|:|..|.|..|....... |:..||.|
  Rat   438 ERDLVTRPDSPPQQLKSPFQ-PVRDNSLA 465

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mirr	NP_001261778.1	Homeobox_KN	242..281	CDD:283551	37/38 (97%)
Irx1	NP_001100801.1	Homeobox_KN	145..184	CDD:283551	37/38 (97%)
		SDA1	<194..>252	CDD:283052	16/71 (23%)
		IRO	309..326	CDD:214716	9/23 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	86	1.000	Domainoid score	I7886
eggNOG	1	0.900	-	-		E1_KOG0773
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D351833at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11211
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	8	7.880