DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mirr and Mkx

DIOPT Version :9

Sequence 1:	NP_001261778.1	Gene:	mirr / 39441	FlyBaseID:	FBgn0014343	Length:	682	Species:	Drosophila melanogaster
Sequence 2:	NP_808263.2	Gene:	Mkx / 210719	MGIID:	2687286	Length:	354	Species:	Mus musculus

Alignment Length:	158	Identity:	55/158 - (34%)
Similarity:	78/158 - (49%)	Gaps:	37/158 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   174 DQP---PFYANPAGIDLKENLVAGASPWPYPSMYHPYDAAFAGYPFNSYGMDLNGAR---RKNAT 232
            |.|   |....|.|..||:||          |:.|           ...|...||.:   ::.|.
Mouse    35 DNPHTGPEVGIPDGPPLKDNL----------SLRH-----------RRTGARQNGGKVRHKRQAL 78

  Fly   233 RETTSTLKAWLNEHKKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLK---KENKMTWEPR- 293
            ::....||.||.:|:.||||||.|||:||:.::|||.|||.||||||||||   ::..::|..|
Mouse    79 QDMARPLKQWLYKHRDNPYPTKTEKILLALGSQMTLVQVSNWFANARRRLKNTVRQPDLSWALRI 143

  Fly   294 ---NRVDDDDA---NIDDDDDKNTEDND 315
               |:....:|   ::..|.|..:||.:
Mouse   144 KLYNKYVQGNAERLSVSSDGDSCSEDGE 171

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mirr	NP_001261778.1	Homeobox_KN	242..281	CDD:283551	26/38 (68%)
Mkx	NP_808263.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	18..50		5/14 (36%)
		Homeobox_KN	88..127	CDD:368670	26/38 (68%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	157..183		4/15 (27%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	243..302
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0773
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810