Protein Alignment mirr and Meis2

DIOPT Version :10

• Sequence 1: NP_001261778.1
• Gene: mirr / 39441
• FlyBaseID: FBgn0014343
• Length: 682
• Species: Drosophila melanogaster
• Sequence 2: XP_011237639.1
• Gene: Meis2 / 17536
• MGIID: 108564
• Length: 559
• Species: Mus musculus
• Alignment Length: 376
• Identity: 90/376 - (23%)
• Similarity: 128/376 - (34%)
• Gaps: 102/376 - (27%)

  Fly    83 SAGLPALSLVGAPPPGPHSSAPG-GAPAPGAGNPPNRCCDTGRTIYTDPVSGQTICSCQYDMLNY 146
            |||.|      .|..|.|:|..| .:...||..     .:....:...|::.:|.| ....|...
Mouse   248 SAGTP------GPSSGGHASQSGDNSSEQGASE-----TEADHLLLWKPMTDRTGC-VSVQMSRE 300

  Fly   147 QRLAAAGG----VPLGVYPEGMSAYLSGIAADQPPFYA-NPAGIDLKENLVAGASPWPYPSMYHP 206
            .|..:..|    .||    |.:      |...||||.. :.||.|..:|.||.      |.....
Mouse   301 DREESREGKHSPQPL----ENI------IIPCQPPFRGESEAGGDGLDNSVAS------PGTGDD 349

  Fly   207 YDAAFAGYPFNSYGMDLNGARRKNA---TRETTSTLKAWLNEHKKNPYPTKGEKIMLAIITKMTL 268
            .|.            |.:..|:|..   .:..|:.::|||.:|..:|||::.:|..||..|.:|:
Mouse   350 DDP------------DKDKKRQKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTI 402

  Fly   269 TQVSTWFANARRRLKKENKMTWEPRNRVDDDDANIDDDDDKNTEDNDLLDAKDSGVGSTDDKDRS 333
            .||:.||.|||||:                    :....|::.....|||...|...:...:.:.
Mouse   403 LQVNNWFINARRRI--------------------VQPMIDQSNRAGFLLDPSVSQGAAYSPEGQP 447

  Fly   334 GRLGDMMTD-------RPGESNNSEWSESRPGSPNGSPDLYDRPGSMPPGAHPLFHPAALHH--- 388
              :|..:.|       ||....:........|.|.|..  ..:|...||...|  ||..|.|
Mouse   448 --MGSFVLDGQQHMGIRPAGLQSMPGDYVSQGGPMGMG--MAQPSYTPPQMTP--HPTQLRHGPP 506

  Fly   389 -------HFRPPA----GSPPDIAAYHHHQQQLLQQHQQAQQNSLQTAVGG 428
                   |...||    |.||.      |....:........||:...|||
Mouse   507 MHSYLPSHPHHPAMVMHGGPPT------HPGMTMSAQSPTMLNSVDPNVGG 551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mirr	NP_001261778.1	Homeobox_KN	243..281	CDD:428673	17/37 (46%)
Meis2	XP_011237639.1	Meis_PKNOX_N	129..213	CDD:465140
		Homeobox_KN	377..415	CDD:428673	17/37 (46%)