back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment mirr and pknox1.2

DIOPT Version :10

Sequence 1:	NP_001261778.1	Gene:	mirr / 39441	FlyBaseID:	FBgn0014343	Length:	682	Species:	Drosophila melanogaster
Sequence 2:	XP_707868.2	Gene:	pknox1.2 / 170445	ZFINID:	ZDB-GENE-020123-1	Length:	445	Species:	Danio rerio

Alignment Length:	327	Identity:	73/327 - (22%)
Similarity:	109/327 - (33%)	Gaps:	133/327 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 PGARSTSPCGPSAGLPALSLVGAPPPG----PHSSAPGGAPAPGAGNPPNRCCDTGRTIYTDPVS 132
            ||    ||..||...|.....||..|.    |.|:...|.....|.||....  ||.|:| .||:
Zfish   175 PG----SPYSPSPTQPQNPFTGAMSPQGIVVPASALQQGNVTVTAVNPTQMV--TGGTVY-QPVT 232

  Fly   133 GQTICSCQYDMLNYQRLAAAGGVPLG-VYPEGMSAYLSGIAADQPPFYANPAGIDLKENLVAGAS 196
            ..|                    |.| |..:.:|.....|...|       ..:.|.::|
Zfish   233 VVT--------------------PQGQVVTQTLSPGTVRIQNSQ-------LQLQLNQDL----- 265

  Fly   197 PWPYPSMYHPYDAAFAGYPFNSYGMDLNGARRKNATRETTSTLKAWLNEHKKNPYPTKGEKIMLA 261
                 |.:...|.:             :.|:|....:..|:.:::||.:|..:||||:.||..:|
Zfish   266 -----SFFSQEDGS-------------SKAKRGILPKHATNVMRSWLFQHIGHPYPTEDEKKQIA 312

  Fly   262 IITKMTLTQVSTWFANARRRL----------------KK--------------------ENKMTW 290
            :.|.:||.||:.||.|||||:                ||                    :.::|.
Zfish   313 LQTNLTLLQVNNWFINARRRILQPMLDASSSDTPKSKKKTPQTRPLQRFWPNSLASSVSQQQVTM 377

  Fly   291 EPRNRV-------------------------------DDDDANIDDDDDKNTEDNDL----LDAK 320
            |....|                               ||||.:.::|:|.:...:|:    |:..
Zfish   378 EDGTTVTVGVGEDGLQTLSSDGATLAMQQVMMGGHSEDDDDEDDEEDEDTDPSHSDMSRLGLETS 442

  Fly   321 DS 322
            ||
Zfish   443 DS 444

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.