DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment caup and TGIF2LX

DIOPT Version :9

Sequence 1:	NP_524046.2	Gene:	caup / 39440	FlyBaseID:	FBgn0015919	Length:	693	Species:	Drosophila melanogaster
Sequence 2:	NP_620410.3	Gene:	TGIF2LX / 90316	HGNCID:	18570	Length:	241	Species:	Homo sapiens

Alignment Length:	176	Identity:	53/176 - (30%)
Similarity:	83/176 - (47%)	Gaps:	29/176 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   229 RRKNATRESTATLKAWLSEHKKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWE 293
            |:.|...||...|:.|:.:|:...||::.||.||:..|.::|.|:|.||.|||||:..:  |..:
Human    53 RKGNLPAESVKILRDWMYKHRFKAYPSEEEKQMLSEKTNLSLLQISNWFINARRRILPD--MLQQ 115

  Fly   294 PKNKTEDDDDGMMSDDEKEKDAGDGGKLSTEAFDPGNQ---------------LIKSELGKAEKE 343
            .:|      |.::. .:..|||......||||..|...               |.|.::.: ||:
Human   116 RRN------DPIIG-HKTGKDAHATHLQSTEASVPAKSGPSGPDNVQSLPLWPLPKGQMSR-EKQ 172

  Fly   344 VD--SSGDQKLDLDREPHNLVAMRGLAPYATPPGAHP-MHAAYSSY 386
            .|  |:..|||....:|...|.:...:| ::|....| .||.:||:
Human   173 PDPESAPSQKLTGIAQPKKKVKVSVTSP-SSPELVSPEEHADFSSF 217

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
caup	NP_524046.2	Homeobox_KN	244..283	CDD:283551	17/38 (45%)
caup	NP_524046.2	IRO	455..472	CDD:214716
TGIF2LX	NP_620410.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..58		2/4 (50%)
		Homeobox_KN	68..107	CDD:283551	17/38 (45%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	126..210		22/85 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.000