DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment caup and TOS8

DIOPT Version :9

Sequence 1:	NP_524046.2	Gene:	caup / 39440	FlyBaseID:	FBgn0015919	Length:	693	Species:	Drosophila melanogaster
Sequence 2:	NP_011419.1	Gene:	TOS8 / 852783	SGDID:	S000003064	Length:	276	Species:	Saccharomyces cerevisiae

Alignment Length:	222	Identity:	64/222 - (28%)
Similarity:	92/222 - (41%)	Gaps:	47/222 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    85 VGGDV-PVGLSSAAQDL-PSRGSCCENGRPIITDPVSGQTVCSCQYDPARLAIGGYSRMALPSGG 147
            ||..| ||.:||....: ||.....:|...|:|..:.       ||.    .|...:|..:.:|.
Yeast    54 VGSPVNPVPVSSPVFFIGPSPQRSIQNHNAIMTQNIR-------QYP----VIYNNNREVISTGE 107

  Fly   148 VG-VGVYGGPYPSNEQNPYPSIGVDNSAFYAP--LSNPYGIKD-------TSP-----------S 191
            .. :...|||..::.|..|..|...|  ||..  |:.|:.:.:       |:|           |
Yeast   108 RNYIITVGGPPVTSSQPEYEHISTPN--FYQEQRLAQPHPVNESMMIGGYTNPQPISISRGKMLS 170

  Fly   192 TEMSAWTSASLQSTTGYYSYDPTLAAYGYGPNYDLAARRKNATRESTATLKAWLSEHKKNPYPTK 256
            ..:|  |::...|..||.:.:....|:|         :|.|..:.:.:.|..||.||..|||||.
Yeast   171 GNIS--TNSVRGSNNGYSAKEKKHKAHG---------KRSNLPKATVSILNKWLHEHVNNPYPTV 224

  Fly   257 GEKIMLAIITKMTLTQVSTWFANARRR 283
            .||..|...|.:|..|:|.||.|||||
Yeast   225 QEKRELLAKTGLTKLQISNWFINARRR 251

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
caup	NP_524046.2	Homeobox_KN	244..283	CDD:283551	21/38 (55%)
caup	NP_524046.2	IRO	455..472	CDD:214716
TOS8	NP_011419.1	Homeobox_KN	212..251	CDD:399131	21/38 (55%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0773
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900