Protein Alignment caup and IRX3

DIOPT Version :9

• Sequence 1: NP_524046.2
• Gene: caup / 39440
• FlyBaseID: FBgn0015919
• Length: 693
• Species: Drosophila melanogaster
• Sequence 2: XP_005256196.1
• Gene: IRX3 / 79191
• HGNCID: 14360
• Length: 529
• Species: Homo sapiens
• Alignment Length: 586
• Identity: 170/586 - (29%)
• Similarity: 234/586 - (39%)
• Gaps: 150/586 - (25%)

  Fly    61 PGAVSQSSHHAGHKGLSTSPAEDVVGGDVPVGLSSAAQDLPSRGSCCENGRPIITDPVSGQTVCS 125
            |||...|...||.:|                ||.:.|.:|.:.||.              ..|.|
Human    20 PGAAGGSGGSAGARG----------------GLGAGASELNASGSL--------------SNVLS 54

  Fly   126 CQYDPARLAIGGYSRMALPSGGVGVGVYGGPYPSNEQNPYPSIGVDNSAFYAPLSNPYGIKDTSP 190
            ..|.      ..|:..|..:...|.|.: .||.: |...:|.:|..           |.:|| ||
Human    55 SVYG------APYAAAAAAAAAQGYGAF-LPYAA-ELPIFPQLGAQ-----------YELKD-SP 99

  Fly   191 STEMSAWTSASLQSTTGYYSYDPTLAAYGYGPNYDLAARRKNATRESTATLKAWLSEHKKNPYPT 255
            ..:..|..:|.......:|.|    ..|.:|.    .:|.||||||||:||||||:||:||||||
Human   100 GVQHPAAAAAFPHPHPAFYPY----GQYQFGD----PSRPKNATRESTSTLKAWLNEHRKNPYPT 156

  Fly   256 KGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWEPKNKTEDDDD--GMMSDDEKEKDAGDG 318
            |||||||||||||||||||||||||||||||||||||.|:::|:::.:  |...::|.|::..:.
Human   157 KGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPRSRTDEEGNAYGSEREEEDEEEDEED 221

  Fly   319 GKLSTEAFDPGNQLIKSELGKAEKEVDSSG------DQKLDLDR------EPHNLVAMRGLAPYA 371
            ||...|       |.:.|||..|::....|      |:::||:.      ||.  :::.|.|...
Human   222 GKRELE-------LEEEELGGEEEDTGGEGLADDDEDEEIDLENLDGAATEPE--LSLAGAARRD 277

  Fly   372 TPPGAHPMHAAYSSYAQSHNTHTHPHPQQMQHHQQQQQQQQNQQQLQHHQMD----QPYYHPGGY 432
            ...|..|:       :.|.|:                ..:.:.:.|:...:.    .|...|...
Human   278 GDLGLGPI-------SDSKNS----------------DSEDSSEGLEDRPLPVLSLAPAPPPVAV 319

  Fly   433 GQEESGEFAAQKNPLSRDCGIPVPA-----SKPKIWSVADTAAC-----KTPPPTAAYLGQNFYP 487
            ...     :....|:|.|...|.||     .||||||:|:||..     ::||      |....|
Human   320 ASP-----SLPSPPVSLDPCAPAPAPASALQKPKIWSLAETATSPDNPRRSPP------GAGGSP 373

  Fly   488 PS-----SADQQLPHQPLQQHQQQQLQQLQQQQQHHHHPHHHHP-----HHSMELGSPLSMMSSY 542
            |.     ||.|..|........:.....|.:.....:.|....|     |....|||....:...
Human   374 PGAAVAPSALQLSPAAAAAAAHRLVSAPLGKFPAWTNRPFPGPPPGPRLHPLSLLGSAPPHLLGL 438

  Fly   543 AGGSPYSRIPTAYTEAMGMHLPSSSSSSSST----GKLPPTHIHPAPQ----RVGFPEIQPDTPP 599
            .|.:.:.....|:.....   |...:...|.    .||..|...|.|:    ||..|...|...|
Human   439 PGAAGHPAAAAAFARPAE---PEGGTDRCSALEVEKKLLKTAFQPVPRRPRPRVLTPRAHPTVKP 500

  Fly   600 Q 600
            |
Human   501 Q 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
caup	NP_524046.2	Homeobox_KN	244..283	CDD:283551	36/38 (95%)
		IRO	455..472	CDD:214716	11/26 (42%)
IRX3	XP_005256196.1	Homeobox_KN	145..184	CDD:283551	36/38 (95%)
		IRO	344..359	CDD:214716	9/14 (64%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0773
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D351833at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11211
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	5	4.970