Protein Alignment caup and TGIF1

DIOPT Version :10

• Sequence 1: NP_524046.2
• Gene: caup / 39440
• FlyBaseID: FBgn0015919
• Length: 693
• Species: Drosophila melanogaster
• Sequence 2: NP_775299.1
• Gene: TGIF1 / 7050
• HGNCID: 11776
• Length: 286
• Species: Homo sapiens
• Alignment Length: 299
• Identity: 77/299 - (25%)
• Similarity: 102/299 - (34%)
• Gaps: 87/299 - (29%)

  Fly   229 RRKNATRESTATLKAWLSEHKKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWE 293
            ||.|..:||...|:.||.||:.|.||::.||.:|:..|.::..||..||.||||||..:
Human    52 RRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRRLLPD------ 110

  Fly   294 PKNKTEDDDDGMMSDDEKEKDAGDGGKLSTEAFDPGNQLIKSELGKAEKEVDS----SGDQKL-- 352
                       |:..|.|               || ||...|..|....|..|    .|.:..
Human   111 -----------MLRKDGK---------------DP-NQFTISRRGAKISETSSVESVMGIKNFMP 148

  Fly   353 DLDREP-HNLVA------MRGLAPYATPPG---AHPMHAAYSSYAQSHNTHTHPHPQQMQHHQQQ 407
            .|:..| |:..|      .|.|:|..:.||   |.|.       ...|.|.|
Human   149 ALEETPFHSCTAGPNPTLGRPLSPKPSSPGSVLARPS-------VICHTTVT------------- 193

  Fly   408 QQQQQNQQQLQHHQMDQPY--YHPGGYGQEESGEFAAQKNPLSRDCGIPVPASKPKIWSVADTAA 470
                        ...|.|:  ....|.||....:..|.||........|....|....:...:..
Human   194 ------------ALKDVPFSLCQSVGVGQNTDIQQIAAKNFTDTSLMYPEDTCKSGPSTNTQSGL 246

  Fly   471 CKTPPPTAAYLGQNFYPPSSADQQLPHQPLQQHQQQQLQ 509
            ..|||||...|.|:|    |..|.|....|::..:.:||
Human   247 FNTPPPTPPDLNQDF----SGFQLLVDVALKRAAEMELQ 281

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
caup	NP_524046.2	Homeobox_KN	245..283	CDD:428673	17/37 (46%)
		IRO	455..472	CDD:214716	1/16 (6%)
TGIF1	NP_775299.1	Homeobox_KN	68..106	CDD:428673	17/37 (46%)