Protein Alignment caup and Irx5

DIOPT Version :9

• Sequence 1: NP_524046.2
• Gene: caup / 39440
• FlyBaseID: FBgn0015919
• Length: 693
• Species: Drosophila melanogaster
• Sequence 2: NP_061296.1
• Gene: Irx5 / 54352
• MGIID: 1859086
• Length: 484
• Species: Mus musculus
• Alignment Length: 589
• Identity: 165/589 - (28%)
• Similarity: 223/589 - (37%)
• Gaps: 187/589 - (31%)

  Fly   117 PVSGQTVCSC-QYDPARLAIGGYSRMALPSGGVGVGVYGG----PYPSNEQNPYPSIGVD----N 172
            |.:...:.|| .|..:.::......:...|.|.....|.|    ..||...|.:...|.|    .
Mouse    11 PSASLALYSCPAYSTSVISGPRTDELGRSSSGSAFSPYAGSTAFTAPSPGYNSHLQYGADPAAAA 75

  Fly   173 SAFYAPLSNPYGIKDTSPSTEMSAWTSASLQSTTGYYSYDPTLAAYGYG-PNYDLAARRKNATRE 236
            :|.::.:.:||   |.:|          .:..:.||:.|...|.:|.|| |.|     ||||||:
Mouse    76 AAAFSYVGSPY---DHTP----------GMAGSLGYHPYAAPLGSYPYGDPAY-----RKNATRD 122

  Fly   237 STATLKAWLSEHKKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWEPKNKTEDD 301
            :||||||||:||:|||||||||||||||||||||||||||||||||||||||||||.|:|::||:
Mouse   123 ATATLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWTPRNRSEDE 187

  Fly   302 DD----GMMSDDE----KEKDAGD------GGKLSTEAFDPGNQLIKSELGKAEKEVD---SSGD 349
            ::    .:..:||    |.:|.||      ||  :.:....|.:.::..|..|.||.:   |..|
Mouse   188 EEEENIDLEKNDEDEPQKPEDKGDLEGPESGG--AEQKATAGCERLQGPLSPAGKETEGSLSDSD 250

  Fly   350 QKLDLDREPHNLVAMRGLAPYATPPGAHPMHAAYSSYAQSHNTHTHPHPQQMQHHQQQQQQQQNQ 414
            .|.......|:.:.....|..::|.|  |..|..:..|..|...:.|.|..
Mouse   251 FKESSSEGRHDELPRPPRAGESSPAG--PATARLAEDAGPHYPASVPAPGP-------------- 299

  Fly   415 QQLQHHQMDQPYYHP-GGYGQEESGEFAAQKNPLSRDCGIPVPASKPKIWSVADTAACKTPPPTA 478
                         || .|.....||..:...:|.......|...:|||:||:|:.|
Mouse   300 -------------HPSAGELPPGSGGSSVIHSPPPPPPPPPAVLAKPKLWSLAEIA--------- 342

  Fly   479 AYLGQNFYPPSSADQQLPHQPLQQHQQQQLQQLQQQQQHHHHPHHHHPHHSMELGSPLSMMSSYA 543
                      :|:|:                                             :....
Mouse   343 ----------TSSDK---------------------------------------------VKDGG 352

  Fly   544 GGSPYSRIPTAYTEAMGMHLPSSSSSSSSTGKLPPTHIHPAPQRVGFPEIQPDTPPQTPPTMKLN 608
            |||..|..|.......|..|..|.:|             |||.....|..|...|
Mouse   353 GGSEGSPCPPCPGPMGGQTLGGSRAS-------------PAPAPARSPSAQCPFP---------- 394

  Fly   609 SSGGSSSSSGSSHSSSMHSVTPVTVASMVNILYSNTDSGYG-HGHSHGH-GHGHGHGLGHGHGLG 671
                    .|:..|..::...|....      |:|    || .||.||| |.|.....|.|   .
Mouse   395 --------GGTVLSRPLYYTAPFYPG------YTN----YGSFGHLHGHPGPGPSPTAGPG---S 438

  Fly   672 HGHG 675
            |.:|
Mouse   439 HFNG 442

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
caup	NP_524046.2	Homeobox_KN	244..283	CDD:283551	36/38 (95%)
		IRO	455..472	CDD:214716	7/16 (44%)
Irx5	NP_061296.1	Homeobox_KN	130..169	CDD:283551	36/38 (95%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	176..393		63/324 (19%)
		IRO	328..345	CDD:214716	7/35 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	424..443		8/22 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0773
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	181	1.000	Inparanoid score	I3968
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11211
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	5	4.920