Protein Alignment caup and Irx4

DIOPT Version :10

• Sequence 1: NP_524046.2
• Gene: caup / 39440
• FlyBaseID: FBgn0015919
• Length: 693
• Species: Drosophila melanogaster
• Sequence 2: NP_061373.1
• Gene: Irx4 / 50916
• MGIID: 1355275
• Length: 515
• Species: Mus musculus
• Alignment Length: 572
• Identity: 177/572 - (30%)
• Similarity: 233/572 - (40%)
• Gaps: 149/572 - (26%)

  Fly    94 SSAAQDLPSRGS---CCENGRPIITD---PVSGQTVCSCQYDPARLAIGGYSRMALPSGGVGVGV 152
            |||.|.|.:..|   |||:|...:.|   ..|.|....|....:||.  ..:|..|.| ...:||
Mouse    11 SSAPQFLMTTNSLSTCCESGGRTLADSGPAASAQAPVYCPVYESRLL--ATARHELNS-AAALGV 72

  Fly   153 YGGPYPSNE-QNPYPSIGVDNSAFYAPLSNPYGIKDTSPSTEMSAWTSASLQST--TGYYSYDPT 214
            ||.||.|:: ...|.:.|.:.||||:  .|.:..||.:.|:.      |.|..|  ..||.|:|.
Mouse    73 YGSPYGSSQGYGNYVTYGSEASAFYS--LNSFESKDGTGSSH------AGLPPTAAAAYYPYEPA 129

  Fly   215 LAAYGYG--PNYDLAARRKNATRESTATLKAWLSEHKKNPYPTKGEKIMLAIITKMTLTQVSTWF 277
            |:.|.|.  ...|...||||||||:|:||||||.||:||||||||||||||||||||||||||||
Mouse   130 LSQYPYDRYGTVDSGTRRKNATRETTSTLKAWLQEHRKNPYPTKGEKIMLAIITKMTLTQVSTWF 194

  Fly   278 ANARRRLKKENKMTWEPKNKTEDDDDGMMSDDEKEKDAGDGGKLSTEAFDPGNQLIKSE--LGKA 340
            |||||||||||||||.|:||..|:.......:|:|  ||:     .|:.:...:..|||  .||.
Mouse   195 ANARRRLKKENKMTWPPRNKCADEKRPYGEGEEEE--AGE-----EESREEPLKSAKSEGHAGKD 252

  Fly   341 EKEVDSSGDQKLD-LDREPHNLVAMRGLAPYATPPGAHPMHAAYSSYAQSHNTHTHPHPQQMQHH 404
            :||::.|..:..| ||.|..............:.|...|..:......:..:|
Mouse   253 DKELELSDLEDFDPLDAETSECELKTPFQSLDSGPERIPASSDGPGTGKEAST------------ 305

  Fly   405 QQQQQQQQNQQQLQHHQMDQPYYHPGGYGQEESGEFAAQKNPLSRDCGIP-------VPA----- 457
                            .:..|....||...:  |:....:|.|.....:|       .||
Mouse   306 ----------------TLRMPLGTAGGAVMD--GDLERARNCLRSTVVVPDSGAEGGPPACEAKL 352

  Fly   458 ------------SKPKIWSVADTAACKTPPPTAAYLGQNFY-----------------PPSSADQ 493
                        :||:|||:|.||..    ..|..|.|..:                 |.||...
Mouse   353 TFAQAGAPPNLETKPRIWSLAHTATA----AAATALSQTEFPSCMLKRQGPTGVSATTPASSPAV 413

  Fly   494 QLPHQPLQQHQQQQLQQLQQQQQHHHHPHHHHPHHSMELGSPLSMMSSYAGG---SP---YSRIP 552
            ..|...|.:||.                            ||::.:.::..|   .|   :|.:.
Mouse   414 TAPSGALDRHQD----------------------------SPVTSLRNWVDGVFHDPILRHSTLN 450

  Fly   553 TAYTEAMGMHL-PSSSSSSSSTGKLPPTHIHPAPQRVGFPEIQPDTPPQTPP 603
            .|:..|.|..| |.....:...|    |::...|....||   |..|...||
Mouse   451 QAWATAKGALLDPGPLGRNLGAG----TNVLTTPLACSFP---PTVPQDVPP 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
caup	NP_524046.2	Homeobox_KN	245..283	CDD:428673	35/37 (95%)
		IRO	455..472	CDD:214716	10/33 (30%)
Irx4	NP_061373.1	Homeobox_KN	162..200	CDD:428673	35/37 (95%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	205..258		21/59 (36%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	278..307		3/56 (5%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	398..425		6/26 (23%)