DRSC - DRSC Integrative Ortholog Prediction Tool

DRSC/TRiP Functional Genomics Resources

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Protein Alignment caup and MEIS1

DIOPT Version :10

Sequence 1:	NP_524046.2	Gene:	caup / 39440	FlyBaseID:	FBgn0015919	Length:	693	Species:	Drosophila melanogaster
Sequence 2:	NP_002389.1	Gene:	MEIS1 / 4211	HGNCID:	7000	Length:	390	Species:	Homo sapiens

Alignment Length:	34	Identity:	10/34 - (29%)
Similarity:	18/34 - (52%)	Gaps:	5/34 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 DEIDIDCDGFINQEEFATICRSS-SSAVEIREAF 94
            |...::|.|::..|    :||.| ::..|.|.:|
Human    16 DWSQVNCSGYVQLE----VCRGSPANVTEARLSF 45

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
caup	NP_524046.2	Homeobox_KN	245..283	CDD:428673
caup	NP_524046.2	IRO	455..472	CDD:214716
MEIS1	NP_002389.1	Meis_PKNOX_N	108..192	CDD:465140
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	190..279
		Homeobox_KN	291..329	CDD:428673
		Interaction with DNA. /evidence=ECO:0000305\|PubMed:26550823, ECO:0000305\|PubMed:28473536	299..329
		Required for transcriptional activation. /evidence=ECO:0000250	335..390
Blue background indicates that the domain is not in the aligned region.

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