Protein Alignment caup and irx1a

DIOPT Version :10

• Sequence 1: NP_524046.2
• Gene: caup / 39440
• FlyBaseID: FBgn0015919
• Length: 693
• Species: Drosophila melanogaster
• Sequence 2: NP_997067.2
• Gene: irx1a / 403019
• ZFINID: ZDB-GENE-040707-1
• Length: 426
• Species: Danio rerio
• Alignment Length: 514
• Identity: 152/514 - (29%)
• Similarity: 207/514 - (40%)
• Gaps: 173/514 - (33%)

  Fly    76 LSTSPAEDVVGGDVPVGLSSAAQDLPSRGSCCENGRPIITDPVSGQTVCSCQYDPARLAIGGYSR 140
            ||.|.|  |.|||.|..|:.:     ||....|                          |||.:.
Zfish    12 LSASQA--VYGGDRPGVLTPS-----SRAGSAE--------------------------IGGSAS 43

  Fly   141 MALPSGGVGVGVYGGPYPSNEQN--PYPSIGVDNSAFYAPLSNPYGIKDTSPSTEMSAWTSASLQ 203
            .|..:....:|:|  ||..|...  ||.|..:   |.::.:.:.|.:|| ||....:::.:   .
Zfish    44 AAAAAVSSVLGMY--PYAHNYSAFLPYTSADL---ALFSQMGSQYDLKD-SPGVHPASFAA---H 99

  Fly   204 STTGYYSYDPTLAAYGYGPNYDLAARRKNATRESTATLKAWLSEHKKNPYPTKGEKIMLAIITKM 268
            ::..:|.|    ..:.||.    .||.||||||||:||||||:||:|||||||||||||||||||
Zfish   100 TSPAFYPY----GQFQYGD----PARPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKM 156

  Fly   269 TLTQVSTWFANARRRLKKENKMTWEPKNKTEDDDDGMMSDDEKEKDAGDGGKLSTEAFDPGNQLI 333
            |||||||||||||||||||||:||..::|  ||::...||:|     ||
Zfish   157 TLTQVSTWFANARRRLKKENKVTWGARSK--DDENIFGSDNE-----GD---------------- 198

  Fly   334 KSELGKAEKEVDSSGDQKLDLDREPHNLVAMRGLAPYATPPGAHPMHAAYSSYAQSHNTHTHPHP 398
             :|..:.|:|:|.   :.:|:|:...|                                    ..
Zfish   199 -AEKNEDEEEIDL---ESIDIDKIDDN------------------------------------DG 223

  Fly   399 QQMQHHQQQQQQQQNQQQLQHHQMDQPYYHPGGYGQEESGEFAAQKNPLSRDCGIPVPAS-KPKI 462
            .|.....:.::.:....|.:.|...:|        .:.:.......:| .|..|..||.| ||||
Zfish   224 DQSNEEDEDKRAELESLQEKRHASKEP--------SDGNNNTTRVLSP-GRQGGFQVPVSNKPKI 279

  Fly   463 WSVADTAACKTPPPTA-----------------------------------AYLGQN--FYPPSS 490
            ||:|:||   |.|.:|                                   |:||||  ....|.
Zfish   280 WSLAETA---TSPDSAQKPTSPSVPVSHPAFLPSHGLYTCQIGKFHNWTNGAFLGQNSLLNVRSF 341

  Fly   491 ADQQLPHQPLQQHQQQ----QLQQLQ----QQQQHHHHPHHHHPHHSMELGSPLSMMSS 541
            ......:.|.||.|||    .||.|.    .:......|.|....:.:...||...:.|
Zfish   342 LGVNQHNHPAQQQQQQTGPASLQVLSAGNTDKMPEDLSPKHIDRENVLRNESPTQPLKS 400

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
caup	NP_524046.2	Homeobox_KN	245..283	CDD:428673	35/37 (95%)
		IRO	455..472	CDD:214716	12/17 (71%)
irx1a	NP_997067.2	Homeobox_KN	133..171	CDD:428673	35/37 (95%)
		IRO	<276..289	CDD:214716	10/15 (67%)