DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment caup and pknox2

DIOPT Version :9

Sequence 1:	NP_524046.2	Gene:	caup / 39440	FlyBaseID:	FBgn0015919	Length:	693	Species:	Drosophila melanogaster
Sequence 2:	NP_705940.1	Gene:	pknox2 / 386959	ZFINID:	ZDB-GENE-031118-112	Length:	474	Species:	Danio rerio

Alignment Length:	309	Identity:	63/309 - (20%)
Similarity:	105/309 - (33%)	Gaps:	136/309 - (44%)

- Green bases have known domain annotations that are detailed below.

  Fly   154 GGPYPSNE----------QNPYPSI-----GVDNSAFYAPLSNPYGIKDTSPSTEMSAWTSASLQ 203
            ||||..::          |:..||:     .|::|....| :.|....:.|       .|:.:.|
Zfish   180 GGPYSPSQTSLGLQQDLLQSSSPSLTSVSSTVNSSGIVVP-AGPLQQNNIS-------MTTINSQ 236

  Fly   204 STTGYYSYDPTLAAYGYGP------------------NYDLAA-------RRKN----ATRESTA 239
            ..:|...|.|.......|.                  |.||::       :.||    ..:.:|.
Zfish   237 VVSGGTLYQPVAMVTSQGQVLTQGLPQGTIQIQNNQVNLDLSSLLDGDDKKSKNKRGVLPKHATN 301

  Fly   240 TLKAWLSEHKKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRR-------------------LK 285
            .:::||.:|..:||||:.||..:|..|.:||.||:.||.|||||                   :|
Zfish   302 IMRSWLFQHLMHPYPTEDEKRQIAAQTNLTLLQVNNWFINARRRILQPMLDASNPDPAPKAKKMK 366

  Fly   286 KENKMT---W-----------------------------------------------------EP 294
            .:::.|   |                                                     |.
Zfish   367 SQHRPTQRFWPDSIVAGVLQTHGTNNSDNSLGMDGLQPLSSDSATLAMQQAMLGGTDDSMDGTEE 431

  Fly   295 KNKTEDDDDGMMSDDEKEKDAGDGGKLSTEAFDPGNQLIKSELGKAEKE 343
            :::.|::|:|:..||::|.|         |..:...|:|:.:||....|
Zfish   432 EDEEEEEDEGLDEDDDEEDD---------EEHEASRQMIRRDLGLNHNE 471

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
caup	NP_524046.2	Homeobox_KN	244..283	CDD:283551	20/38 (53%)
caup	NP_524046.2	IRO	455..472	CDD:214716
pknox2	NP_705940.1	Meis_PKNOX_N	95..178	CDD:293102
pknox2	NP_705940.1	Homeobox_KN	306..345	CDD:283551	20/38 (53%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0773
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900