Protein Alignment caup and Irx2

DIOPT Version :9

• Sequence 1: NP_524046.2
• Gene: caup / 39440
• FlyBaseID: FBgn0015919
• Length: 693
• Species: Drosophila melanogaster
• Sequence 2: NP_001034594.1
• Gene: Irx2 / 306657
• RGDID: 1309834
• Length: 474
• Species: Rattus norvegicus
• Alignment Length: 546
• Identity: 170/546 - (31%)
• Similarity: 224/546 - (41%)
• Gaps: 153/546 - (28%)

  Fly   130 PARLAI-----GGYSRMALP-SGGVGVGVYGGPYPSNEQNPYPSIGVDNSAFYAPLSNPYGIKDT 188
            |..||:     .|.|.:|.| |..:.....|..:     :|||.    ::||.|..:..:|
  Rat    12 PGSLALYSCPAYGASALAAPRSEELARSASGSAF-----SPYPG----SAAFTAQAATGFG---- 63

  Fly   189 SP---STEMSAWTSASLQS------------TTGYYSYDP-TLAAYGYGPNYDLAARRKNATRES 237
            ||   |.:.:|..:|...|            .||..||.| ..|||.|..|.  .|.||||||::
  Rat    64 SPLQYSADAAAAAAAGFPSYMGSPYDTHTTGMTGAISYHPYGSAAYPYQLND--PAYRKNATRDA 126

  Fly   238 TATLKAWLSEHKKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWEPKNKTEDDD 302
            ||||||||:||:|||||||||||||||||||||||||||||||||||||||||||.|:||:||:|
  Rat   127 TATLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPRNKSEDED 191

  Fly   303 ----DGMMSDDEKEKDAGDGGKLSTEAFDPGNQLIKSELGKAEKEVDSSGDQKLDLDREPHNLVA 363
                |...|.:|....|.||.:.|.|  |.|..|          .|||..|.....:.:...|..
  Rat   192 EDEGDASRSKEENPDKAQDGTETSAE--DEGISL----------HVDSLTDHSCSAESDGEKLPC 244

  Fly   364 MRGLAPYATPPGAHPMHAAYSSYAQSHNTHTHPHPQQMQHHQQQQQQQQNQQQLQHH-------- 420
            ..|          .|:..:.|              :.....:..:.::.::.:.:..
  Rat   245 RAG----------DPLCESGS--------------ECKDKFEDLEDEEDDEDECERDLVPPKPVT 285

  Fly   421 -----QMDQPYYHPGGYGQEESGEFAAQKNPL-SRDC-GIPVPASKPKIWSVADTAACKTPPPTA 478
                 .::.|...|........|  :..|.|| ||.. |.|.||||||:||:|:.|......|:
  Rat   286 SSPLTGVEAPLLSPAPEAAPRGG--SGGKTPLGSRTSPGAPPPASKPKLWSLAEIATSDLKQPS- 347

  Fly   479 AYLGQNFYPPSSADQQLPHQPLQQHQQQQLQQLQQQQQHHHHPHHHHPHHSMELGSPLSMMSSYA 543
              ||....||.......|                                 ...|:|       .
  Rat   348 --LGPGCGPPGLPAAAAP---------------------------------ASSGAP-------P 370

  Fly   544 GGSPYSRIPTAYTEAMGMHLPSSS---SSSSSTGKLPPTHIHPAPQRVGFPEIQPDTPPQTP-PT 604
            ||||||..|     .:|.||..:|   .:.::.|.|     :.|.|..|.  ::.:|...:| .|
  Rat   371 GGSPYSASP-----LLGRHLYYTSPFYGNYTNYGNL-----NAALQGQGL--LRYNTAASSPGET 423

  Fly   605 MKLNSSGGSSSSSGSSHSSSMHSVTP 630
            :.......|.:....|||...|...|
  Rat   424 LHAIPKAASDAGKAGSHSLESHYRPP 449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
caup	NP_524046.2	Homeobox_KN	244..283	CDD:283551	36/38 (95%)
		IRO	455..472	CDD:214716	10/16 (63%)
Irx2	NP_001034594.1	COG5576	<115..217	CDD:227863	73/103 (71%)
		Homeobox_KN	133..172	CDD:283551	36/38 (95%)
		IRO	325..342	CDD:214716	10/16 (63%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11211
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010