DRSC/TRiP Functional Genomics Resources

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Protein Alignment caup and Tgif2

DIOPT Version :9

Sequence 1:NP_524046.2 Gene:caup / 39440 FlyBaseID:FBgn0015919 Length:693 Species:Drosophila melanogaster
Sequence 2:NP_775572.1 Gene:Tgif2 / 228839 MGIID:1915299 Length:237 Species:Mus musculus


Alignment Length:309 Identity:72/309 - (23%)
Similarity:102/309 - (33%) Gaps:112/309 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly   229 RRKNATRESTATLKAWLSEHKKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWE 293
            ||.|..:||...|:.||..|:.|.||::.||:.|:..|.:::.|:..||.||||||..:      
Mouse    21 RRGNLPKESVKILRDWLYLHRYNAYPSEQEKLSLSGQTNLSVLQICNWFINARRRLLPD------ 79

  Fly   294 PKNKTEDDDDGMMSDDEKEKDAGDGGKLSTEAFDPGNQLIKSELGKAEKEVDSSGDQKLDLDREP 358
                       |:..|.|               ||....|....|||                  
Mouse    80 -----------MLRKDGK---------------DPNQFTISRRGGKA------------------ 100

  Fly   359 HNLVAMRGLAPYATPPGAHPMHAAYSSYAQSHNTHTHPHPQQMQHHQQQQQQQQNQQQLQHHQMD 423
                     :..|.|.|:.|...|.|.          |.|..|               |......
Mouse   101 ---------SDVALPRGSSPSLLAVSV----------PAPTNM---------------LSLSVCS 131

  Fly   424 QPYYHPGGYGQEESGEFAAQKNPLSRDCGIPVPASKPKIWSVADTAA-----CKTPPPTAAYLGQ 483
            .|.:  .|.|::.:..|...:  |.....:..|||...:.:.|:..:     ..|||||      
Mouse   132 MPLH--SGQGEKPAAPFPQVE--LESPKALVTPASTLTLLTRAEAGSPTGGLFNTPPPT------ 186

  Fly   484 NFYPPS------SADQQLPHQPLQQHQQQQLQQLQQQQQHHHHPHHHHP 526
               ||.      |:.|.|....||:..:.:|    |:||....|..|.|
Mouse   187 ---PPEQDKDDFSSFQLLVEVALQRAAEMEL----QKQQEPAPPLLHTP 228

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
caupNP_524046.2 Homeobox_KN 244..283 CDD:283551 16/38 (42%)
IRO 455..472 CDD:214716 4/21 (19%)
Tgif2NP_775572.1 Homeobox_KN 36..75 CDD:368670 16/38 (42%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 87..106 7/45 (16%)
Repressive function 103..237 38/168 (23%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 171..196 7/33 (21%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 212..237 7/21 (33%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0773
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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