DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment caup and Meis3

DIOPT Version :9

Sequence 1:	NP_524046.2	Gene:	caup / 39440	FlyBaseID:	FBgn0015919	Length:	693	Species:	Drosophila melanogaster
Sequence 2:	XP_036008636.1	Gene:	Meis3 / 17537	MGIID:	108519	Length:	400	Species:	Mus musculus

Alignment Length:	204	Identity:	59/204 - (28%)
Similarity:	86/204 - (42%)	Gaps:	56/204 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    87 GDVPVGLSSAAQDLPSRGSCCENGRPIITDPVSGQTVCSCQYDPARLAIGGYSRMALPSGGVGVG 151
            |.:|:.|....:|    |||.|:    :.|     ...||...|.:...  :.|....||.|.:|
Mouse   192 GKMPIDLVIEDRD----GSCRED----LED-----YAASCPSLPDQNTT--WIRDHEDSGSVHLG 241

  Fly   152 VYGGPYPSNEQNPYPSIGVDNSAFYAPLSNPYGIKDTSPSTEMSAWTSASLQSTTGYYSYDPTLA 216
            .   |.||:  ....|...|||:     ....|: |||.::..||
Mouse   242 T---PGPSS--GGLASQSGDNSS-----DQGDGL-DTSVASPSSA-------------------- 275

  Fly   217 AYGYGPNYDL-AARRKNATR-----ESTATLKAWLSEHKKNPYPTKGEKIMLAIITKMTLTQVST 275
                |.:.|| ..||:|..|     .:|..::|||.:|..:|||::.:|..||..|.:|:.||:.
Mouse   276 ----GEDEDLDLERRRNKKRGIFPKVATNIMRAWLFQHLSHPYPSEEQKKQLAQDTGLTILQVNN 336

  Fly   276 WFANARRRL 284
            ||.|||||:
Mouse   337 WFINARRRI 345

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
caup	NP_524046.2	Homeobox_KN	244..283	CDD:283551	18/38 (47%)
caup	NP_524046.2	IRO	455..472	CDD:214716
Meis3	XP_036008636.1	Meis_PKNOX_N	99..205	CDD:406806	4/16 (25%)
Meis3	XP_036008636.1	Homeobox_KN	305..344	CDD:399131	18/38 (47%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0773
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900